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143 Cards in this Set

  • Front
  • Back
bilirubin
orange-yellow pigment formed during destruction of erythrocytes that is taken up by liver cells to form bilirubin and eventually excreted in the feces
elevated bilirubin in blood produces yellowing of the skin (jaundice), indicates liver damage or disease
bolus
mass of masticated food ready to be swallowed
exocrine
gland that secretes its products through excretory ducts to the surface of an organ or tissue or into a vessel
sphincter
circular band of muscle fibers that constricts a passage or closes a natural opening of the body
triglycerides
organic compound, a true fate, that is made of one glycerol and three fatty acids
combine with proteins in blood to form lipoproteins
bucca
cheeks
Functions of the liver
you need it to live!
bile production (aids in fat digestion)
removing glucose from blood to synthesize glygocen and retain it for later use
storing vitamins (B12, A, D, E, and K)
destroying or transforming toxic products into less harmful compounds
maintaining nrmal glucose levels in the blood
destroying old erythrocytes and releasing bilirubin
synthesizing proteins that circulate in the blood, such as albumin for fluid balance and prothrombin and fibrinogen for goagulation
Pancreas
secretes insulin into bloodstream
produces digestive enzymes that pass into duodenum through the pancreatic duct
trypsin - digests proteins
amylase - digests starch
lipase - digests triglycerides
gallbladder
storage for bile!
into duodenum through common bile duct
cystic duct merges with hepatic duct from liver to form common bile duct
without bile, fat digestion isn't possible
or/o
stomat/o
mouth
stomatitis - inflammaiton of the mouth
gloss/o
lingu/o
tongue
cheil/o
labi/o
lip
cheiloplasty - surgical repair of defective lip
dent/o
odont/o
teeth
gingivo
gums
sial/o
saliva, salivary gland
sialolith - calculus formed in a salivary gland or duct
gastr/o
stomach
gastralgia - stomachache
pylor/o
pylorus
pylorospasm - involuntary contraction of the pyloric sphincter
enter/o
intestine, usually small
sigmoid/o
sigmoid colon
col/o and colon/o are colon
rect/o
rectum
rectocele - herniation or protrusion of the rectum
procto
anus, rectum
proctologist - treats disorders of colon, rectum, and anus
ano
anus
hepato
liver
pancreat/o
pancreas
pancreatolysis - destruction of the pancreas
cholangio
bile vessel - small terminal portion of the bild duct
chol/e
bile, gall
cholelith - gallstone
cholecyst/o
gallbladder
choledoch/o
bile duct
-emesis
vomit
-iasis
abnormal condition
-orexia
appetite
-pepsia
digestion
dydpepsia - difficult or painful digestion
-phagia
swallowing, eating
-prandial
meal
postprandial - after a meal
-rrhea
discharge, flow
steatorrhea - discharge of fat in fecal matter
Peptic Ulcer Disease
PUD
sore in stomach or duodenum or lower esophagus
cause - erosion of protective mucous membrane caused by infection with H. pylori bacteria, tissue exposed to acids and enzymes, forms ulcer.
risk factors - smoking, tobacco, stress, caffeine use, steroids, aspirin, NSAIDs.
untreated can creat a hole
ulcerative colitis
chronic inflammatory disease of the colon
inflammation involves only the mucosal lining of the colon, which exhibits erythema and numerous hemorragic ulcerations
uniformly involved, no evidence of healthy mucosal tissue
characterized by profuse, watery diarrhea containing varrying amounts of blood, mucus, and pus
may require surgical creation of an opening (stoma) for bowel evacuation to a bag
associated with increased risk of colon cancer
Hernia
protrusion of organ, tissue, or structure through the wall of the cavity in which it is naturally contained
generally applied to protrusions of abdominal organs (viscera)
inguinal hernia - lump, reducible in early stages, if blood supply is cut off, a strangulated hernia may develop leading to necrosis with gangrene
an umbilical hernia is a protrusion of part of the intestine at the navel
in diaphragm:
diaphragmatic hernia - congenital hernia
hiatal hernia - lower part of esophagus and top of stomach slides back up into the esophagus, causing heartburn, chest pain, and difficulty swallowing
may cause gastroesophageal reflux disease (GERD)
Intestinal obstruction
mechanical - intestinal contents preventing from moving forward due to an obstacle or barrier that blocks the lumen. tumors, scar tissue, intestinal twisting (volvolus), intestinal "telescoping" (intusssceptions), strangulated hernias, or presence of foreign bodies, such as fruit pits and gallstones

Nonmechanical - peristalsis is impaired and intestinal contents can't be propelled through the bowel. after abdominal surgeris or with spinal cord lesions

Severity depends on area affected, amount of occlusion within the lumen, and the amount of disturbance in blood flow to the bowel.
treatment 0 decompress bowel with nasogastric tube, IV with electrolytes may be initiated to correct imbalance
complete mechanical obstruction requires surgical interventions
Hemorrhoids
enlarged veins in the mucous membrane of the anal area
bleed, hurt, or itch
internal or external to rectal area
caused by - abdominal pressure
high-fiber diet and water for prevention
relief from cold compresses, sitz baths, stool softeners, analgesic ointments
treatment - surgical removal
Hepatitis
causes - exposure to toxic substances (alcohol), obstruction in bile ducts, metabolic diseases, autoimmune disease, bacterial or viral infections
A-E (A,B, C most common)
A - infectious hepatitis, contaminated food, water, or milk
B - serum hepatitis, transmitted by routes other than the mouth (blood/sex), vaccine
C - transmitted by routes other than the mouth (blood/sex), no vaccine, may be asymptomatic for years, or only mild

treatment - intiviral drugs, no cure. scarring becomes serious enough to warrant liver transplantation
Jaundice because liver can't remove bilirubin (yellow compound formed when erythrocytes are destroyed)
Diverticulosis
small, blisterlike pockets (diverticula) develop in inner lining of large intestine and may balloon through intestinal wall, usually in sigmoid
don't cause problems unless they become inflammed (diverticulitis)
pain in LLQ, constipation or diarrhea, fever, abdominal swelling, occasional blood in bowel movements
mild - rest, antibiotics, and changes in diet
sever - surgical, excision of affected segment
Stomach cancer
common where food preservation is problematic
neoplasm from epithelial or mucosal lining of stomach in the form of a cancerous gladular tumor (gastric adenocarcinoma)
persistent indigestion
other types - esophageal, hepatocellular, pancreatic carcinomas
Colorectal cancer
one of the most common types in US
epithelial lining of colon or rectum
changes in bowel habits, blood and mucus in stools, rectal or abdominal pain, anemia, weight loss, obstruction, and performation
anorexia
lack of appetite, resulting in inability to eat
not anorexia nervosa, which is a complex psychogenic eating disorder characterized by an all-consuming desire to remain (or be) thin
appendicitis
inflammation of the appendix, usually due to an obstruction or infection
appendectomy within 24-48 hours of first symptoms
Ascites
abnormal accumulation of fluid in abdominal cavity, most commonly as a result of chronic liver disease
associated with cirrhosis of liver
borborygmus
rumbling or gurgling noises from passage of gas through liquid contents of intestine!
gurgly tummy
cachexia
physical wasting that includes loss of weight and muscle mass and is commonly associated with AIDS and cancer
Cholelithiasis
presence or formation of gallstones in gallbladder or common bile duct
cirrhosis
scarring and dysfunction of the liver caused by chronic liver disease
usually chronic alcoholism
also toxins, infectious agents, metabolic disease, and circulatory disorders
colic
spasm in any hollow or tubular soft organ, esp. in the colon, accompanied by pain
Crohn disease
form of inflammatory bowel disease IBD, usually of ileum, regional enteritis
certain inflammatory pattern. fever, cramping, diarrhea, and weight loss
dysentery
inflammation of intestine, esp. colon, caused by ingesting water or food containing chemical irritants, bacteria, protozoa, or parasites, and results in bloody diarrhea
dysphagia
inability or difficulty in swallowing, aphagia
eructation
producing gas from the stomach, usually with a characteristic sound, aka belching
burps!
fecalith
fecal concretion
flatus
flAtus
gas in GI tract, expelling of air from a body orifice, esp. the anus
gastroesophageal reflux disease
GERD
backflow of gastric contents into esophagus due to malfunction of the sphincter muscle at the inferior portion of the esophagus
halitosis
foul-smelling breath
poor oral hygiene, infections, ingestion of certain foods, use of tobaco, or systemic disease such as diabetes or liver disease
Hematemesis
vomiting of blood from bleeding in the stomach or esophagus
ulcer, esophageal varices (dilation of veins)
Irritable bowel syndrome
IBS
symptom complex marked by abdominal pain and altered bowel function (constipation, diarrhea, or alteration of them) for which no organic cause can be determined, aka spastic colon
anxiety and stress are aggravating factors
malabsorption syndrome
symptom complex of small intestine - impaired passage of nutrients, minerals, or fluids through intestinal villi into blood or lymph
melena
passage of dark-colored, tarry stools, due to presence of blood altered by intestinal juices
obstipaiton
severe constipation, maybe from intestinal obstruction
oral leukoplakia
formation of white spots or patches on the mucous membrane of lips, tongue, cheek caused by irritation
precanceous condition assoc. with smoking
pyloric stenosis
stricture or narrowing of pyloric sphincter at outlet of stomach, causing obstruction that blocks the flow of food into small intestine
steatorrhea
passage of fat in large amounts in the feces due to failure to digest and absorb it
pancreatic disease or malabsorption syndrome
nasogastric intubation
tube to relieve gastric distention by removing gas, food, or gastric secretions; instill medication, food, or fluids; or obtain specimen for analysis
anastomsis

ileorectal
intestinal
surgical joining of two ducts, vessels, or bowel segments to allow flow from one to another
ileorectal - connect ileum and rectum after total colectomy, sometimes performed in treatment of ulcerative colitis
intestinal - connect two portions of intestines, enteroenterostomy
bariatric surgery
group of procedures that treat morbid obesity
vertical banded gastroplasty - stapling of upper stomach and insertion of band that restricts food consumption and delays its passage from the pouch, causing a feeling of fullness
Roux-en-Y gastric bypass - stapling stomach and shortening jejunum and connecting it to the small stomach pouch, causing the base of the duodenum leading from the nonfunctional portion of the stomach to form a Y configuration, decreases pathway of food, reducing absorption of calories
colostomy
opening of portion of colon through abominal wall to its outside surface in order to divert fecal flow to a colostomy bag
lithotripsy
procedure for crushing a stone and eliminating its fragments surgically or using ultrasonic shock waves
extracorporeal shock-wave lithotripsy - use of shock waves as a noninvasive method to break up stones in gallbladder or biliary ducts
polypectomy
excision of a polyp
examined for abnormal or cancerous cells
pyloromyotomy
incision of the longitudinal and cirular muscles of the pylorus, used to treat hypertrophic pyloric stenosis
gastrointestinal endoscopy
visual exam of GI with fiberoptic instrument with magnifying lens and light source, to identify abnormalities incl. bleeding, ulcerations, and tumors
hepatities panel
panel of blood tests that identifies the specific virus (Hep A. HBV, or HCV) causing hepatitis by testing serum using antibodies to each of these antigens
Liver function tests (LFTs)
group of blood tests that evaluate liver injury, funciton, and conditions comonly associated with biliary tract
serum bilirubin
measurement of lvl of bilirubin in blood
elevated indicates excessive destruction of erthrocytes, liver, disease, or biliary tract obstruction
Stool culture
test to id microorganisms or parasites in feces
stool guaiac
test that applies guaiac to a stool sample to detect presence of blod, aka Hemoccult
computed tomography
CT
imaging technique achieved by rotating an x-ray emitter around the area to be scanned and measuring the intensity of transmitted rays from diff angles
lower gastrointestinal series
radiographic images of the rectum and colon folowing administration of barium into the rectum; aka lower GI series, or barium enema
oral cholecystography
OCG
radiographic images taken of gallbladder after admin of contrast material containing iodine,
magnetic resonance cholangiopancreatography
MRI used to visualize the biliary and pancreatic ducts and gallbladder
no contrast medium needed
sialography
radiologic exam of salivary glands and ducts
ultrasonography
abdominal
endoscopic
US
high-frequency sound waves directed at soft tissue and reflected as "echoes" to produce an image on a monitor of an internal body structure
abdominal - US vis of abdominal aorta, liver, gallbladder, bile ducts, pancreas, kidneys, ureters, and bladder to diagnose and locate cycts, tumors, and malformations and document progresion of diseases and guid insertion of instruments during surgical procedures
endoscopic - combines endoscopy and US to examine and obtain images of digestive tract, endoscope emits ultrasound to produce images
upper gastrointestinal series
UGIS
radiographic images of esophagus, stomach, and small intestine following oral admin of barium
Antacids
counteract or neutralize acidity
treat and prevent heartburn and acid reflux
calcium carbonate - mylanta, rolaids, tums
antidiarrheals
control loose stools and relieve diarrhea by absorbing excess water in bowel or slowing peristalsis in intestinal tract
antiemetics
control nausea and vomiting by blocking nerve impulses ot vomiting center
some act by hastening movement of food through digestive tract
antispasmodics
decrease GI spasms by slowing peristalsis and motility throughought GI tract
for IBS, spastic colon, and diverticulitis
Laxatives
treat constipation by increasing peristaltic activity in large intestine or increasing water and electrolyte secretion into bowel to induce defecation
Ba
barium
BaE, BE - barium enema
BM
bowel movement
HAV, HBV, HCV
hepatitis viruses
also
HDV
HEV
R/O
rule out
stat
immediately
Solid and liquid components of blood
red blood cells (erythrocytes)
White blood cells (leukocytes)
Platelets (thrombocytes)
plasma - 92% water, plasma proteins (albumins, globulins, and fibrinogen), gases, nutrients, salts, hormones, waste materials
(serum = plasma without fibrinogen and clotting elements)
The life of red blood cells
Erythrocytes transport o2 and CO2
erythropoisis - RBCs decrease in size and extrude their nuclei, develop iron-containing hemoglobin for carrying
live about 120 days - release hemoglobin and cell fragments
Three types of granulocytes
leukocytes with granules
neutrophils - lilac color, polymorphonuclear leukocytes because their nuclei are segmented, phagocytic - ingest and destroy bacteria, most numerous and first to site

Eosinophils - stain red (affinity for acid dye), Detoxification - numerous during allergic reactions and animal parasite infestation

Basophils - dark purple (affinity for basic dye), release histamines and heparin at sites of injury - inflammatory process (blood flow) & prevent blood from clotting at site
Agranulocytes
arise in bone marrow, mature in lymph
specific immune system
nuclei don't form lobes, mononuclear leukocytes

Monocytes - mildy phagocytic in vessels, they exit and become macrophages - phagocytes that ingest pathogens, dead cells, and other debris

Lymphocytes - B cells, T cells, natural killer (NK) cells
B & T: acquired immunity, recognize and destroy threats
NK: generalized defense, kill with chemicals, effective against cancer cells and cells harboring pathogens
Platelets
smallest formed elements, thrombocytes
initiate blood clotting
Hemostasis (control of bleeding) - series of reactions, platelets become sticky and form barrier, release thromboplastin -> fibrinogen forms fibrin strands, net traps cells into thrombus or blood clot
Blood types
Type A: plasma has B antibodies (41% of population)
Type B: plasma has A antibodies (10% of pop)
Type AB: neither A nor B antibodies (4% of pop)
Type O: blood cells have neither A nor B antibodies, so plasma has A AND B antibodies (45% of pop)
eosin/o
dawn (rose-colored)
erythro
red
plas/o
formation, growth
poikil/o
irregular, varied
sider/o
iron
-penia
decrease, deficiency
allo-
other, differing from the normal
aniso-
unequal, dissimilar
Anemia
deficiency of erythrocytes or hemoglobin in the blood
caused by lack of iron, blood loss, blood cell destruction, decreased blood formation and faulty hemoglobin production
s/s - dyspnea, weakness, tachycardia, pallor, hypotension, and commonly, a slight fever
Aplastic (hypoplastic) anemia
serious form associated with bone marrow failure and resulting in erythropenia, leukopenia, and thrombocytopenia
caused by autoimunne disorders, chemotherapy, radiation therapy, and exposure to certain cytotoxic agents
follic-acid deficiency anemia
inability to produce sufficient RBCs due to lack of folic acid, B vit essential for erythropoiesis
caused by insufficient folic acid intake due to poor diet, impaired absorption, prolonged drug therapy, or increased requirements (pregnancy or rapid growth)
hemolytic aenemia
destruction of RBCs, commonly resulting in jaundice
associated with some inherited immune and blood (sickle cell anemia) disorders, medications, and incompatible transfusions
Iron-deficiency anemia
lack of sufficient iron in RBCs
caused by a greater demand for stored iron than can be supplied, usually as a result of inadequate dietary iron intake or malabsorption of iron
Pernicious anemia
chronic, progressive anemia found mostly in people older than age 50 due to lack of sufficient vitamin B12, needed for blood cell development

commonly the result of insufficient intrinsic factor in the stomach (absorption of vit B12)
sickle cell anemia
inherited anemia that causes RBCs to become crescent shaped when oxygen levels are low
caused by a defect in the gene responsible for hemoglobin synthesis
must inherit trait from both parents to have disorder
Hemophilia
bleeder's disease
hereditary disorder in which blood clotting mechanism is impaired
Hemophilia A - deficiency in clotting factor VIII
Hemophilia B - deficiency in clotting factor IX
deficiency from mild - severe
found most commonly in men, women carriens but usually don't have symptoms
mild - nosebleeds, easy bruising, bleeding from gums
severe - seepage within muscles, blood in joints (hemarthrosis) associated with pain and deformity
uncontrolled bleeding can lead to shock and death, treat with deficient factor
Disseminated intravascular coagulation (DIC)
abnormal activation of the proteins involved in blood coagulation, causing small blood clots to form in vessels and cutting off the supply of oxygen to distal tissues
eventually, clotting proteins are exhausted, leading to profuse bleeding, even with slightest trauma
hemoglobinopathy
any disorder caused by abnormalities in the hemoglobin molecule (sickle cell anemia)
lymphadenopathy
any disease of the lymph nodes
Thrombocythemia
overproduction of platelets, leading to thrombosis or bleeding disorders due to platelet malformations
thrombocytopenia
abnormal decrease in platelets caused by low production of platelets in the bone marrow or increased destruction of platelets in the blood vessels (intravascular), spleen (extravascular), or liver (extravascular)
von willebrand disease
bleeding disorder caused by a deficiency of von Willebrand factor, a "sticky" protein that lines the blood vessels and reacts with platelets to forma a plug that leads to clot formation
blood culture
test to determine the presence of pathogens in the bloodstream
complete blood count (CBC)
series of tests that includes hemoglobin, hematocrit; red and white blood cell counts, platelet count, and differential count; also called hemogram
screening for anemias, coagulation disorders, and infections
partial thromboplastin time PTT
test that measures the length of time it takes blood to clot to screen for deficiencies of some clotting factors; aka activated partial thromboplastin time
prothrombin time
test that measures the time it takes for prothrombin to form a clot; aka pro time
shilling test
test used to diagnose pernicious anemia by determining if the body properly absorbs vitamin B12 through the digestive tract
bone marrow MRI
highly sensitive imaging procedure that detects lesions and changes in bone tissue and bone marrow, esp. in multiple myeloma
anticoagulants
prevent blood clot formation by inhibiting the synthesis or inactivating one or more clotting factors
prevent DVT and postoperative clot formation and decrease the risk of stroke
heparin, warfarin
antifibrinolytics
neutralize fibrinolytic chemicals in the mucus membranes of the mouth, nose, and urinary tract to prevent the breakdown of blood clots
aminocaprioc acid
used to treat serious bleeding
fat-soluble vitamins
prevent and treat bleeding disorders resulting from a lack of prothrombin, which is commonly caused by vitamin K deficiency
phytonadione
thrombolytics
dissolve blood clots by destroying their fibrin strands
alteplase, streptokinase
AB
Ab, ab
antibody, abortion
APC
antigen presenting cell
BMT
bone marrow transplant
CBC
complete blood count
DIC
disseminated intravascular coagulation
diff
differential count (wbcs)
Hb, Hgb
Hemoglobin