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310 Cards in this Set

  • Front
  • Back

This is the study of form

Anatomy

This is the study of function

Physiology

What are the subdisciplines in anatomy?

Gross anatomy


Histology


Cytology

This is the study of structures that can be seen with the naked eye

Gross anatomy

This is microscopic anatomy-- examination of tissues with a microscope

Histology

Study of structure and function of cells

Cytology

This is cutting and separation of organs to study their relationships

Cadaver dissection

This is the study of more than one species to analyze evolutionary trends

Comparative anatomy

What are the names for examining the structure of the human body?

Inspection


Palpation


Auscultation


Percussion

This means that the anatomy is visible to the naked eye

Gross anatomy

About what percent of human anatomy conforms to the anatomy found in textbooks?

About 70%

What is the typical reference man?

22 years old, 154 lbs, light physical activity and consumes 2800 kcals/day

What is the typical reference woman?

Same as a man except 128 lbs and 2000 kcals/day

Normal position of organs

Situs Solitus

Complete reversal of all organs

Situs Inversus

The heart being situated on the right side of the body instead of the left

Dextrocardia

Malposition of any organ (like the kidney)

Situs persus

Physiology of the nervous system

Neurophysiology

Physiology of hormones

Endocrinology

Mechanisms of disease

Pathophysiology

This is the study of different species

Comparative physiology

This man was a Greek physician and the "Father of Medicine"

Hippocrates

What is the hierarchy of complexity?

Organism


organ system


organs


tissues


cells


organelles


molecules


atoms

Single, complete individual

Organism

Group of organs with a unique college function

Organ system

Structure composed of 2 or more tissue types that work together to carry out a particular function

Organ

A mass of similar cells and cell products that form a discrete region of an organ that performs a specific function

Tissues

The smallest units of an organism that carry out all the basic functions of life.

Cells

Nothing simpler than a cell is considered alive

Cells

Microscopic structures in cells that carry out individual functions

Organelles

Proteins, fats, and DNA. Composed of at least 2 atoms

Molecules

The smallest particles with unique identities

Atoms

What are the characteristics of life?

Organization


Cellular composition


Metabolism and excretion


Responsiveness and movement


Homeostasis


Development


Reproduction


Evolution

Far high level of organization in living things and the breakdown of this characteristic of life is accompanied by disease and death.

Organization

Compartmentalization in one or more cells

Cellular Composition

The sum of all internal chemical changes

Metabolism

Complex molecules synthesized from simple ones

Anabolism

Complex molecules broken down into simple ones

Catabolism

This characteristic of life produces chemical waste that becomes toxic upon accumulation

Metabolism

This is the elimination of waste from the tissues and removal from the body

Excretion

The is the ability of organisms to sense and react to stimuli

Responsiveness

Most living organisms are capable of some form of self-propelled ____.

Movement

Although the environment around the organism may change, it maintains relatively stable internal conditions

Homeostasis

Change in form and function over time

Development

This part of life consists of 2 different parts: differentiation and growth

Development

This part of development is the transformation of cells with no specific function into cells that are committed to a particular task

Differentiation

This part of development is simply an increase in size

Growth

All living things can produce copies of themselves

Reproduction

All living things exhibit genetic change from generation to generation and therefore evolve

Evolution

This person believed that "stable internal conditions regardless of external conditions" existed

Claude Bernard

This person coined the term "homeostasis"

Walter Cannon

Can there be fluctuation within a limited range around a set point for homeostasis?

Yes

A loss of ____ control causes illness or death

homeostasis

This is when the body senses a change and activates mechanisms to reverse it

Negative feedback loop

Humans do this when the brain senses change in blood temperature

Human thermoregulation

Vessels dilate in the skin and sweating begins

Vasodilation

vessels constrict in the skin and shivering begins

Vasoconstriction

This is shivering

vasoconstriction

This is sweating

Vasodilation

What are the 3 components of a feedback loop?

Receptor, integrating control center, effector

This part of a feedback loop senses change in the body

Receptor

This part of the feedback loop control center that processes the sensory information, 'makes a decision', and directs the response

Integrating control center

This part of the feedback loop carries out the final corrective action to restore homeostasis

Effector

What is another name for a positive feedback loop?

Self-amplifying change

This leads to change in the same direction

Self-amplifying change

When does a positive feedback loop occur?

Childbirth, blood clotting, protein digestion, generation of nerve signals

What's an example of a harmful positive feedback loop?

Temperature above 108 degrees

This was discovered by William Roentgen in 1885

Radiography

This penetrates tissues to darken photographic film beneath the body

Radiography

What makes up over half of all medical imagining?

Radiography

What kind of substances are injected or swallowed and fill hollow structures like blood vessels and intestinal tract to help visualize them?

Radiopaque substances

This is a low-intensity X rays and computer analysis using slice-type imaging.

CT (Computer tomoraphy) Scan

What kind of imaging is used in CT scans

Slice-type imaging

What does PET scan stand for?

Positron Emission Tomography scan

These types of scan assess metabolic statue of tissues and distinguish tissues most active at a given moment

PET scan

How do PET scans work?

1. Inject radioactively labeled glucose


2. Positrons and electrons collide


3. Gamma rays given off


4. Detected by sensor


5. Analyzed by computer


6. Image color shows which tissues were using the most glucose at the moment


7. Damaged tissues appear dark

This medical imaging tool uses slice type image but are superior to a CT scan

MRI

This type of medical imaging is best for soft tissues

MRI

What are the mechanics of MRIs?

1. Alignment and realignment of hydrogen atoms with magnetic field and radio waves.


2. Varying levels of energy given off used by computer to produce an image

This is the second oldest and second most widely used form of medical imaging

Sonography

What is the second most widely used form of medical imaging?

Sonography

What are the mechanics of Sonography?

High frequency sound waves echo back from internal organs

What is a reason to use sonography?

They avoid harm x-rays for obstetrics

This is the position when a person stands erect, feet flat on the floor, arms at sides, palms, eyes, and face facing forward.

Anatomical position

This is the standard frame of reference for anatomical descriptions and dissections

Anatomical position

In this forearm position, palms face upwards, and radius and ulna are parallel

Supine position

In this forearm position, palms face downwards, radius and ulna are crossed

Prone position

This plane divides the body into right and left halves

Sagittal plane

This plane divides the body into front and back portions

Coronal (Frontal) plane

This plane divides the body into upper and lower portions

Transverse plane

Toward the front or belly

Ventral

Toward the back, or spine

Dorsal

Toward the ventral side

Anterior

Toward the dorsal side

Posterior

Above

Superior

Below

Inferior

Toward the medial plane

Medial

Away from the medial plane

Lateral

Closer to the point of attachment or origin

Proximal

Farther from the attachment or origin

Distal

Closer to the body surface

Superficial

Farther from the body surface

Deep

This region is the head, neck, and trunk

Axial region

This is the region of the axial region that is above diaphragm

Trunk

This is the region of the axial region that is below the diaphragm

Abdomen

These regions are the upper and lower limbs

Appendicular region

What are the parts that make up the upper limbs?

Brachium, antebrachium, carpus, manus, digits

What are the parts that make up the lower limbs?

Thigh, crus, tarsus, pes, and digits

What are the 2 major body cavities?

Dorsal body cavity


Ventral body cavity

What are the 2 parts of the dorsal cavity?

Cranial cavity


Vertebral canal

What are cavities that make up the ventral cavity?

Thoracic cavity


Diaphragm


Abdominopelvic cavity

What are body cavities filled with?

Viscera

This is another word for body organs

Viscus

In the thoracic cavity, this word describes "organs separating left from pleural cavities."

Mediastinum

What makes up the mediastinum?

Heart, blood vessels, esophagus, trachea, and thymus

What cavity carries the lungs?

Pleural cavity

This membrane covers the lungs

Visceral pleural

This membrane lines the rib cage

Parietal pleural

This is the pericardial membrane that covers the heart

Visceral pericardium

This is the pericardial membrane that lines the pericardial sac

Parietal pericardium

What separates the abdomen and the pelvic cavity?

The pelvic brim

What cavity contains the GI tract, kidneys, and ureters

Abdominal cavity

What cavity contains the rectum, bladder, urethra, and reproductive organs?

Pelvic cavity

What are the membranes of the abdominopelvic cavity?

Visceral and parietal peritoneum

What membranes suspends the intestines?

The dorsal mesentary

What is the mesentary of the large intestine?

Mesocolon

This membrane hangs from the stomach and transverse colon

Greater omentum

This membrane extends from the stomach to the liver

Lesser omentum

These are spaces found between two tissue layers normally pressed firmly together, but can fill with fluid in unusual circumstances

Potential space

How many organ systems are in your body?

11

The principle organs of this system are skin, hair, nails, and cutaneous glands

Integumentary system

The principle functions of this organ system are: protection, water retention, thermoregulation, vitamin D synthesis, cutaneous sensation, nonverbal communication

Integumentary system

The principle organs of this system are: bones, cartilages, ligaments

Skeletal system

The principle functions of this system are: support, movement, protective enclosure of viscera, blood formation, electrolyte and acid-base balance

Skeletal system

The principle organs of this system are: skeletal muscles

Muscular system

The principle functions of this system are: movement, stability, communication, control of body openings, heat production

Muscular system

The principle organs of this system lymph nodes, lymphatic vessels, spleen ,tonsils, and thymus

Lymphatic System

The principal functions of this organ system are: recovery of excess tissue fluid, detection of pathogens, production of immune cells, defense against disease

Lymphatic System

The principal organs of this system are: nose, pharynx, larynx, trachea, bronchi, lungs

Respiratory system

The principal functions of this organ system are: absorption of oxygen, discharge of carbon dioxide, acid-base balance, and speech

Respiratory system

This principle organs of this system are: the kidneys, ureters, urinary bladder, and urethra

Urinary system

The principle functions of this system are: elimination of wastes, regulation of blood volume and pressure, stimulation of red blood cell formation; control of fluid, electrolyte, and acid-base balance; and detoxification

Urinary system

The principal organs of this system are the brain, spinal chord, nerves, and ganglia

Nervous system

The principal functions of this system are: rapid internal communication, coordination, motor control, and sensation

Nervous system

The principal organs of this system are: pituitary gland, pineal gland, thyroid gland, thymus, adrenal gland, pancreas, testes, and ovaries

Endocrine system

The principal functions of this system are: hormone production, internal chemical communication and coordination

Endocrine system

The principal organs in this system are: heart and blood vessels

Circulatory system

The principal functions of this system are: distribution of nutrients, oxygen, wastes, hormones, electrolytes, heat, immune cells, and antibodies; fluid, electrolyte and acid-base balance

Circulatory system

The principal organs of this system are: teeth, tongue, salivary glands, esophagus, stomach, small and large intestines, liver, gallbladder, pancreas

Digestive systm

The principal functions of this system are: nutrient breakdown and absorption. Liver functions include metabolism of carbohydrates, lipids, proteins, vitamins and minerals; synthesis of plasma proteins, disposal of drugs, toxins and hormones; and cleansing of the blood

Digestive system

What are the parts of Cell Theory?

1. All organisms are composed of cells and cell products.


2. Cell is the simplest functional unit of life.


3. Organisms structure and functions are due to activities of the cells


4. Cells come only from preexisting cells


5. Cells of all species have many fundamental similarities

This cell shape is thin and flat

Squamous

This cell shape is irregularly angular with 4 or more sides

Polygonal

This cell shape is squarish

Cuboidal

This cell shape is taller than wide

Columnar

This cell shape is roud

Spheroid

This cell shape is disc-shaped

Discoid

This cell shape is star-shaped

Stellate

This cell shape is thick in the middle and tapered at the ends

Fusiform

This cell shape is threadlike

Fibrous

What is the size of most human cells?

10-15 micrometers

What are the limitations of cell size?

Cell growth increases volume faster than surface area; nutrient absorption and waste removal utilize surface

This part of the cell defines cell boundaries, controls interactions with other cells, and controls the passage of material in and out of the cell

Plasma membrane

This is an oily film of lipids with diverse proteins embedded in it

Plasma membrane

What % of lipids is the plasma membrane made of?

98%

This part of the plasma membranes is made up of lipids (making up 75% of the lipids of the p.m.) with hydrophilic heads and hydrophobic tails

Phospholipid bilayer

This part of the plasma membrane has molecular motion that creates membrane fluidity.

Phospholipid bilayer

This part of the plasma membrane affects membrane fluidity (a low concentration makes it rigid, high concentration makes it fluid). It makes up 20% of the lipid amount of the p.m.

Cholesterol

This is the carbohydrate coating on a cell surface

Glycocaylx

This part of the plasma membrane contributes to the glycocalyx and make up 5% of the total lipid amount of the p.m.

Glycolipids

These make up 2% of the molecules of the plasma membrane and 50% of the weight

Membrane proteins

These membrane proteins pass completely through the membrane and most are glycoproteins

Transmembrane proteins

These membrane proteins adhere to the membrane surface and are anchored in the cytoskeleton

Peripheral proteins

These use cell communication via chemical signals

Membrane receptors

These part of the cell bind chemicals, like hormones and neurotransmitters, and identify them with receptor specificty

Membrane receptors

In this system, the chemical messenger binds to a surface receptor, receptor activates G protein, G protein binds to adenylate cyclase which converts ATP to cAMP, etc.

2nd messenger system

These parts of the plasma membrane break down chemical messengers to stop their signaling effects and produce second messengers

Membrane enzymes

Do membrane enzymes produce second messengers?

Yes

These are transmembrane proteins with pores, some that constantly open, some that use gated channels that open and close in response to stimuli

Membrane channel proteins

These parts of the plasma membrane are important in nerve signal and muscle contraction

Membrane channel proteins

These use ligland (chemically) regulated genes, voltage related genes, and mechanically regulated genes

Membrane channel proteins

These parts of the plasma membrane are transmembrane proteins that bind to solutes and transfer them across the membrane

Membrane carriers or pumps

These, in the plasma membrane, are carriers that consume ATP

Pumps

These parts of the plasma membrane adhere cells to eachother and to extracellular material

Membrane cell-adhesion molecules

These parts of the plasma membrane enable the body to identify "self" from foreign invaders.

Membrane cell-identity markers

What forms the glycocalyx?

Glycoproteins

What acts as the cells identity tag?

Glycocalyx

This is the unique fuzzy cell surface

Glycocalyx

What does the glycocalyx function as?

Cell recognition


Adhesion


Protection

Is the glycocalyx identical in identical twins?

Yes

These are extensions of the cell membrane that contain actin and function to increase the surface area of the cell and milking action of actin

Microvilli

In microvilli, where are actin filaments found?

In the center of the microvilli

These are hairlike processes, 7-10 micrometers long

Cilia

A single, nonmotile ____ is found on nearly every cell

Cilium

These are sensory in ear, retina, and nasal cavity

Cilia

In motile ____, these beat in waves and power strokes are followed by recovery strokes.

Cilia

What's the structure of the cilia?

9+2 axoneme structure

This is a hereditary disease where chloride pumps fail to create adequate saline layer under mucus.


Thick mucus plugs pancreatic ducts and respiratory tracts.

Cystic fibrosis

This disease causes inadequate absorption of nutrients and oxygen, lung infections, and a life expectancy of age 30.

Cystic fibrosis

These are whiplike structures with axoneme identical to cilium, although much longer than cilium

Flagella

What's the only functional flagellum in the body?

Tail of sperm

Does passive transport require ATP?

No

This is movement down a concentration gradient, filtration and simple diffusion are examples of this

Passive Transport

This is movement against a concentration gradient

Active transport

Does Active Transport require ATP?

Yes

Carrier mediated (facilitated diffusion and active transport) and vesicular transport are example of this kind of transport

Active Transport

This is movement of particles through a selectively permeable membrane by hydrostatic pressure

Filtration

Is filtration active or passive transport?

Passive

Examples of this kind of passive transport are: filtration of nutrients from blood capillaries into tissue fluids and filtration of wastes from the blood in the kidneys

Filtration

This is net movement of particles from an area of high concentration to an area of low concentration, also known as movement down the concentration gradient

Simple diffusion

What are some factors that affect diffusion rates through a membrane?

Temperature, molecular weight, steepness of concentration gradient, membrane surface area, and membrane permeability

What diffuses through the lipid bilayer?

Nonpolar, hydrophobic substances

What diffuses through channel proteins?

Water and hydrophilic solutes

How do cells control permeability?

Through regulating the number of channel proteins

This is diffusion of water through a membrane (from an area of more water to an area of less water)

Osmosis

This is equal to 1 mole of dissolved particles

1 osmole

What is the equation to find osmolarity?

#of osmoles/L of solution

This is the ability of a solution to affect fluid volume and pressure within a cell

Tonicity

This type of solution has a low concentration of nonpermeating solutes (high water concentration)

Hypotonic solution

In this type of solution, cells absorb water and may burst (lyse)

Hypotonic solution

This has a high concentration of nonpermeating solutes and low water concentration

Hypertonic solution

In this tonic situation, cells lose water and crenate

Hypertonic solution

This is a normal saline soltuion

Isotonic solution

This is when proteins carry solutes across a cell membrane

Carrier mediated transport

What are 2 examples of carrier mediated transport?

Facilitated diffusion and active transport

In carrier mediated transport, a ____ binds to a specific receptor site on a carrier protein

solute

How does carrier mediated transport differ from membrane enzymes?

The solutes are unchanged

This is the transport rate when all carrier are occupied

Transport maximum

This type of membrane carrier carries only one solute at a time

Uniporter

This type of membrane carrier carries 2 or more solutes simultaneously in the same direction (cotransport)

Symporter

This carries 2 or more solutes in opposite directions (counter transport)

Antiporter

This sodium potassium pump is an example of which kind of membrane carrier?

Antiporter

This is a transport of solute down a concentration gradient, no ATP required

Facilitated diffusion

How does facilitated diffusion work?

A solute binds to a carrier, it changes shape then releases solute on the other side of a membrane

This pump is needed because Na+ and K+ constantly leak through a membrane

Sodium-potassium pump

How does the Sodium-potassium pump work?

1 ATP is utilized to exchange 3 Na+ pushed out for two K+ brought into the cell

This pump functions in regulation of the cell volume, heat production, maintainence of membrane potential in all cells, and secondary active transport

Sodium-potassium pump

Does secondary active transport use ATP?

No

In the regulation of cell volume of the sodium-potassium pump, what attracts cat ions, causing osmosis?

Fixed anions

What's another name for secondary active transport?

SGLT; sodium-glucose transport protein

This simultaneously binds Na+ and glucose and carries both into the cell at once. It absorbs glucose and prevents it from being wasted in the urine.

SGLT; sodium-glucose transport protein

This type of transport is used to transport large particles or droplets of fluid through membranes in vesicles

Vesicular transport

Does vesicular transport use ATP?

Yes

This is transport out of a cell

Exocytosis

This is transport into a cell

Endocytosis

Engulfing large particles

Phagocytosis

Taking in fluid droplets

Pinocytosis

Taking in specific particles bound to receptors

Receptor-mediated endocytosis

Does pinocytosis occur in all humans?

Yes

In this process, the membrane caves in, and then pinches off into the cytoplasm as a pinocytotic vesicle

Pinocytosis

This is selective endocytosis and have receptor specificity, also called Clathrin-coated vesicle in cytoplasm

Receptor Mediated Endocytosis

This is transport of a substance across a cell

Transcytosis

How this works: receptor mediated endocytosis moves it into a cell and exocytosis moves it out of a cell (transporting it across the cell)

Transcytosis

People with this disease have abnormally low LDL receptors, and therfore their cells absorb less cholesterol than normal

Familial Hypercholesterolemia

If the gene for this disease is inherited from both parents, the sufferer will have a heart attack before age 20 and seldom survive beyond 30 years of age

Familial Hypercholesterolemia

What are the 3 structures in the cytoplasm?

Organelles, Cytoskeleton, and Inclusions

What organelles are not bordered by a membrane?

Ribosome, centrosome, centriole, basal bodies

This is made of microfilaments and microtubules

Cytoskeleton

These are stored products

Inclusions

This is the largest organelle

Nucleus

This is a 2 unit membrane held together by nuclear pores

Nuclear envelope

Made up of chromatin and nucleoli

Nucleoplasm

This is DNA and protein in the nucleus

Chromatin

These are dark masses where ribosomes are produced

Nucleoli

These are parallel flattened membranous sacs covered with ribosomes, continuous with nuclear envelope and smooth ER,

Rough ER

These synthesize packaged proteins, phospholipids, and proteins of plasma membrane

Rough ER

These lack ribosomes, and their cisternae are more tubular and branching.

Smooth ER

These provide: synthesis of membranes, steroids (ovaries and testes), and lipids, detoxification (liver and kidney), and calcium storage (skeletal and cardiac muscle)

Smooth ER

These are granules of RNA and protein. They use directional mRNA to assemble amino acids into proteins specified by the genetic code

Ribosomes

This organelle is a system of flattened sacs that synthesizes carbohydrates, packages proteins, and glycoproteins

Golgi Apparatus

The organelle forms lysosomes, secretory vesicles, and a new plasma membrane

Golgi Apparatus

These are packages of enzymes in a single unit membrane, variable in shape

Lysosomes

Digestion of worn out organelles done by lysosomes

Autophagy

Programmed cell death

Autolysis

These organelles resemble lysosomes but contain different enzymes and they function to neutralize free radicals, detoxify alcohol

Peroxisomes

These are short, cylindrical assemblies of microtubules

Centriole

These are 2 double ring purines

Guanine


Adenine

These are single ring pyrimadines

Uracil, thymine, cytosine

These are all the genes of 1 person

Genome

This is when messenger RNA (mRNA) is formed next to an activated gene

Transcription

mRNA code is 'read' by ribosomal RNA as amino acids are assembled into a protein molecule

Translation

This process converts the alphabet of nucleotides into a sequence of amino acids to create a specific protein

Translation

This is what a cluster of 10-20 ribosomes reading mRNA at one time

Polyribosomes

This is the beginning of a chain of amino acids that determines proteins destination within a cell

Signal peptide

These kind of proteins prevent premature folding, assist in proper folding, and escort protein to final destination

Chaperone proteins

These proteins are produced in response to heat or stress and help damaged protein fold back into correct functional shapes

Stress or heat-shock proteins

This means that each new DNA molecule contains one new helix and one conserved from parent DNA

Semiconservative replication

How long does it take for all 46 chromosomes to be replicated by thousands of polymerase molecules?

6-8 hours

How do you form nucleosomes?

DNA winds around histones

These are changes in DNA structure due to replicaiton error or environmental factors

Mutations

The functions of this process are:
Embryonic development


Tissue growth


Replacement of dead cells


Repair of injured tissues

Mitosis

What are the phases of mitosis?

PMAT

This phase of mitosis is when chromatin coils into genetically identical, paired, and sister chromatids, when the nuclear envelope disintegrates.

Prophase

How many molecules of DNA are there per chromatid?

1

This the phase of mitosis when chromosomes line up on one equator

Metaphase

This phase of mitosis is when daughter chromosomes move towards opposite poles of cells with centromeres leading the way

Anaphase

This phase of mitosis is when new nuclear envelope forms by rough ER, chromatids uncoil into chromatin, mitotic spindle breaks down, and nucleus forms nucleoli

Telophase

This is the division of cytoplasm into 2 cells

Cytokinesis

When do cells divide?

1. When the cells have enough cytoplasm for 2 daughter cells.


2. DNA replicated


3. Adequate supply of nutrients


4. Growth factor simulation


5. Open space due to neighboring cell death

These are abnormal growths, cells multiply faster than they die

Tumors (neoplasms)

This type of tumor is a connective tissue capsule, slow growth, and stays local

Benign

This type of tumor is unencapsulated, fast growing, metastatic, and simulate angiogensis

Malignant

This is cancer of the epithelial cells

Carcinoma

This is cancer of pigment producing skin cells

Melanoma

This is cancer of bone, connective tissue, or muscle

Sarcoma

This is cancer of blood-forming tissues

Leukemia

This is cancer of the lymph nodes

Lymphoma

This kind of oncogenes cause excessive production of growth factors

sis oncogene

This type of oncogene codes for abnormal growth factors

ras oncogene

These are mutated forms of normal growth factor genes called ________

proto oncogenes