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5 Cards in this Set
- Front
- Back
Where does Hematopoietic Stem Cell differentiation occur throughout a life cycle? |
Begins in Yolk sac initially -> migrates to Liver prenatally -> migrates to entire skeleton Red Marrow postnatally -> migrates to axial skeleton in adults. |
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Where does postnatal Hematopoiesis occur? |
In Trabecular Marrow of bonese, which have medullas within that support differentiation, proliferation, maturation of progenitors. |
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What are key features of Hematopoietic Stem Cells? |
Pluripotent, Self-renewing. |
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What triggers differentiation of HPCs? |
Growth factors and CYTOKINES released during immune responses. |
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What does Tri-Lineage refer to? |
Refer to hematopoiesis of Myeloid, Erythroid, and Megakaryocyte differentiations. |