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15 Cards in this Set

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Linoleic acid
18:2 to arachidonic acid omega 6

(9, 12)
linolenic acid
18:3 to DHA omega 3

(9,12,15)
characteristics of essential FA's
humans can't synth dbl bond at omega 6 or less

most human FA's unconjugated

essentials penetrate skin
process of FA series
desaturase (NADPH)
elongase (2NADPH)
-acetate donor is methylmalonyl CoA (ACoA in mito rxns)

Desaturase again
FA series'
omega 6:
-linoleic to DGLA to arachadonic

omega 3:
-linolenic to EHA to DHA

omega 9:
-oleic to meads acid
triene/tetraene ratio
meads/aa
high means defect in FA's
regulation of FA series
mass action
oleic is not essential
will predominate if missing essentials
conjugated FA's
CLA's

desaturase is only 2 carbons
vaccenic acid to rumenic

anticarcinogenic & antiox
rumenic acid
cis 9 trans 11
conjugated FA made in humans from veccinic (sp?)
antiox, anticancer
functions of essential FA products
inflammation
CNS esp 1st 3 mo of life
retina

very fluid- keep membranes fluid
characteristics of transfats
increase LDL, total, TG
decrease HDL
increase CVD
decrease growth rate in children
advers affect CRP, TNF, E select, IL 6 & CAM's
disrupt PG balance
change membrane fluidity
DHA
22:6
(4, 7, 10, 13, 16, 19)

docosahexanoic
EPA
20:5
(4,8,11,14,17)

Eicosapentaenoic acid
DGLA
intermed to arachadonic acid

20:3

Dihomo-gamma-linolenic acid
arachadonic acid
20:4

(5, 8, 11, 14)