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26 Cards in this Set

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What are the MC sites of endometriosis?

1. Ovary


2. Pelvic peritoneum over uterus


3. Anterior/posterior cul-de-sac


What groups are at risk for endometriosis?

1. Delayed childbearing


2. Genetic predisposition with disease in first-degree relative

What do you surgically dx endometriosis?

1. Laparoscopy with implant bx

What are the pathogenesis theories for endometriosis?

1. Retrograde menstruation


2. Vascular and/or lymphatic spread


3. Coelomic metaplasia of multi potential cells

What are some dx clues for endometrisosi?

1. Women who do not respond to NSAIDs or OCs for dysmenorrhea


2. Deep dyspareunia


3. Infertility


4. GI complaints

What are the clinical signs of endometriosis?

1. Uterosacral nodularity palpable on pelvic or rectovaginal exam


2. Fixed uterus or ovary on pelvic exam

What meds should be given on a trial basis when endometriosis is suspected?

1. Doxycycline


2. NSAIDs


3. OCs

What imaging modality should be used first in an evaluation of endometriosis?

1. US

If the trial meds fail to resolve patient complaints, what is the next step?

1. GnRH agonist

What is the next step if the GnRH agonist fails to resolve ssx?

1. Laparoscopy


2. Consultation with pain clinic

What factors should you take into account when you tx endometriosis?

1. Pain control


2. Desire for future pregnancy

What are the medical tx options for endometriosis?

1. OCs--- menstruation


2. Progestions-- suppress menstruation


3. Danazol


4. GnRH agonists

What are the surgical options for the tx of endometriosis?

1. Lysis of adhesions


2. Cauterize impalnts


3. Hysterectomy with ooophorectomy

What should be in the ddx with ssx of endometriosis?

1. PID


2. Pelvic adhesions


3. Dyspareunia


4. Irritable bowel, hematochezia


5. Luteal phase defects, cervical polyps

How do you ultimately arrive at a dx of endometriosis?

1. Dx of exclusion


2. Work-up for other disorders is negative

What is chronic pelvic pain?

1. Pain for 6 months duration


2. Must be of sufficient severity to cause functional disability, interfere with normal activities, or lead to medical care

In what ages is primary dysmenorrhea most common?

1. Late teens or 20's


2. Risk decreases with age

What is the effect of childbearing on risk for primary dysmenorrhea?

1. No risk increase

What are the MCC of primary dysmenorrhea?

1. Endometriosis


2. Adhesions


3. IBS


4. Interstitial cystitis

What cellular mediator is linked to primary dysmenorrhea?

1. Prostaglandin F2-alpha

What post-menopausal conditions can cause primary dysmenorrhea?

1. Genital malignancy


2. DM


3. Intestinal disease

What should be included in the history for primary dysmenorrhea?

1. Medical


2. Surgical


3. Sexual


4. Menstrual


5. Social/family

How do you tx primary dysmenorrhea?

1. Bed rest


2. NSAIDs


3. Heat


4. OMT


5. Exercise


6. OCs


7. Supportive care

What are the MCC of secondary dysmenorrhea?

1. Endometriosis


2. Tumors


3. Inflammation


4. Adenomyosis


5. Leiomyoma

What is adenomyosis?

1. Islands of endometrial tissue in the myometrium

How is adenomyosis best diagnosed?

1. MRI


2. Often at time of hysterectomy--- boggy, enlarged uterus