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21 Cards in this Set

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What does parathyroid hormone does to serum levels of Ca and phosphorus?
Increase Calcium
Decreases Phosphorus
Will respond to low calcium an hi phosphorus
what happens when excess there is EXCESS PTH circulating in blood?
Bone damage
Hypercalcemia
Kidney Damage
Pathophysiology of Hyperparathyroidsm
1. Excessive PTH stimulates transport of calcium into the blood from

- kidney's
- Intestines
- bone

2. Nephrolitiasis - kidney stone which may cause pyelonephritis

3. Myopathy

4. Hypercalcemia stimulates hyprgastrinemia
Hyprgasterinemia can be caused due to HYpercalcemia - T/F
True - hypergastrinemia can caused by high calcium.
High calcium can cause what GI problems?
- abdominal pain
- PUD
- Pancreatitis
parathyroid hormone responds to what?
High phosphorus

LOw calcium

(when phosphorus is high, calcium is excreted)
what causes secondary hyperparathyroidsm
chronic renal failure and hyperphospatemia
Clinical manifestations of HYPer parathyroidsm
- could be asymptomatic
- Bones, Stones
- Moans
- Groans

depression
calcification in eyes
peptic ulcer or gi bleeding
Diagnostics of Hyperparathyroidsm
labs and xrays
- high calcium levels
- low phosphate levels
- high levels of urine phos levels
- high alk. phos (liver bone problems)
- deminaralization of bones, loss of lamina dura @ teeth
Medical management of Hyperparathyroidism
- Hydration (NS) - inhibits reabsorption of calcium by the kidneys, increase calciuria (loop diuretic after hydration is restored)

- NO THIAZIDE diruetics since they retain calcium
- low calcium low Vit D diet
DRUGS

- Plicamycin
- gallium nitrate
- phosphates
- CALCITONIN (thyroid hormone)
- Glucocorticoids
- Etidronate (calcitonin)
DOC for hyperparathyroidism
GALLIUM Nitrate - fewer side effects
what is plicamycin used for and what should u educate the clients
Chemo drug to reduce calcium

plicamycin effect is after 24 hours and lasts about 1-2 weeks
Can Glucocorticoids reduce calcium?
YES - they decrease GI absorption of calcium (also retains Na)
A pt . is given Etidronate ? why is the pt on that med
it is calcitonin to decrease the release of calcium by bones
Nursing management for hypereparathyroidism
risk of fractures
impaired urinary elimination (encourage fluids 3000ml, UO 0.5ml/kg/hr, prevent urolithiasis (cranberry juice, prune juice)

- constipation (high calcium/constipation - also true with Ca channel blockers)

- Imbalanced nutrition less than body requirements
Surgical Management of HYPerarathyroidism
Parathyroidectomy

Autotransplantation

- calcium and vit d supplements
- total recovery is good
- bones heal
- renal disease damage may be irreversible
Complications of parathyroidectomy
- Hypocalcemia can be life threatening - edema reduces function of even the normal tissue remaining
- Respiratory distress r/t experience of surgeon adequate exploration of the neck
Nursing management parathyroidectomy
monitor for
- respiratory distress
- hemorrhage
- hypocalcemia
- obstruction
- laryngeal nerve
- tetany/hormone imbalance
- mild tetany is expected
- tingling of hands and around mouth is expected and temporary
- if tingling is persistant of severe - CALCIUM GLUCONATE
- prevent osteoporosis - eat foods hi in calcium, injection calcium gluconate, oral calcium, ambulation

WALK, WALK walk

LARYNGEOSPASMS - CALCIUM GLUCONATE
DECREASED NEUROMUSCULAT IRRITABILITY IS FOUND IN WHAT
HYPER PARATHYROIDISM
increased neuromuscular activity can lead to TETANY - T/F
True - caused by hypoparathyroidsm
what happens to phosphate and calcium levels in hypo parathyroidsm
low calcium

HIgh phosphate levels