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51 Cards in this Set
- Front
- Back
3 muscle layers of stomach
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1) longitudinal muscle layer (outside)
2) circular muscle layer (middle) 3) oblique muscle layer (inner) |
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gastric pit
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narrow channel
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mucous neck cells
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secretes mucus
protection to preserve epithelial tissues of stomach form HCL acid |
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parietal cells
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secrete HCL acids and intrinsic factor
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HCL acids
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1) denatures proteins
2) converts pepsinogen into pepsin |
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intrinsic factor
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needed for absorption of vit. B12
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chief cells
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secrete pepsinogen (inactive form)
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the hepatic ducts (R & L)from the liver combine to form?
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the common hepatic duct
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common hepatic duct combines with the cystic duct from the GB to form?
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common bile duct
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the common bile duct and the pancreatic duct combine to form?
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hepatopancreatic ampulla
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the hepatopancreatic ampulla empties into the duodenum at ?
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major duodenal papilla
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emulsification
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the dispersion of large lipid globules to smaller, uniformly distributed particles in the presence of bile
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liver
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1) the largest organ w/i the abd. cavity
2) intraperitoneal 3) located in the right hypochondriac region |
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superior portion of the liver is in contact with?
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the inferior portion of the diaphragm
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gallbladder is located in?
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the inferior portion of the liver
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four lobes of the liver
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1) right lobe
2) left lobe 3) quadrate lobe 4) caudate lobe |
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which lobe is the largest?
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right lobe
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functions of the liver
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1) vascular
2) metabolic 3) secretory 4) excretory |
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the functional unit of the liver
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liver lobule
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liver lobule
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constructed around a central vein
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sinusoids
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like channels
microscopic spaces or passages for blood in the liver |
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sinusoids receives
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mixed blood from portal vein and hepatic artery
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portal triad (portal tract)
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1) bile duct
2) portal vein (deoxy. B, lots of nutrients) 3) hepatic artery (oxigenated B) |
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blood flow through the liver and return
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1) hepatic artery (oxy) & hepatic portal vein (deoxy, nutrients rich)
2) liver sinusoids 3) central vein 4) hepatic vein (R & L) 5) inferior vena cava 6) right atrium of heart |
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Kupffer cells in sinusoid
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1) phagocytes & defense
2) clean & filter microorganism |
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hepatocytes
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1) liver cells
2) secrete bile |
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sinusoids
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1) are flanked by the hepatic plates
2) receive blood from the small arterioles 3) always in contact with portal blood |
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how much of blood the liver sinusoids receive per min.?
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total of 1.45L/min
(1.1 L from the portal vein & 350 ml form the arterial system) |
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1.45 L/min. of blood equal to?
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1) 29 % of resting CO
2) 33 % of the total body blood flow |
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Is liver expandable?
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Yes.
(ex) CHF pt (R. heart failure)- hepatomegaly |
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How much of blood the liver normally store?
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450 ml of blood
(almost 10 % of the body's total blood volume) |
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Kupffer cells
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1) clean the blood while it passes along the sinusoids
2) so, no more than 1 % of the bacteria enters the liver |
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carbohydrates metabolism by the liver
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1) stores glycogen
2) converts fructose and galactose into glucose 3) gluconeogenesis 4) formation of many important chemical compounds in the carb. meta. |
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sucrose
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glucose + fructose
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lactose
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glucose + galactose
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maltose
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glucose + glucose
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gluconeogenesis
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the conversion of certain AAs or lactic acids into glucose
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fat metabolism
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1) oxidation of fatty acids to supply energy
2) formation of most lipoproteins 3) synthesis of cholesterol and phospholipids 4) conversion of carbohydrates and proteins into fat |
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~ 80 % of the cholesterol is converted into?
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bile salts
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energy yield of triglycerides
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9 Cal/g
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energy yield of carbohydrates
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4 Cal/g
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protein metabolism
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1) deamination of AAs
2) formation of urea 3) formation of plasma proteins 4) interconversions among the different AAs and other compounds |
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deamination
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1) removal of the amino group from the AA
2) essential to use AAs 3) forms large amounts of ammonia |
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ammonia is also formed by?
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bacteria in the GI tract
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the way to remove ammonia is by?
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uria formation
if ammonia [ ] increased = hepatic coma and death |
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Cori cycle
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the recycling of lactic acid produced by muscle during anaerobic metabolism.
The LA is converted to glucose by the liver. |
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90 % of all plasma proteins are formed in ?
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liver
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liver can synthesize non-essential AAs by using?
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transaminases
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the liver also stores
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1) vitamin A
2) vitamin D 3) vitamin B12 4) iron |
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the liver forms a large proportion of the blood substances used in blood coagulation like
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1) fibrinogen
2) prothrombin 3) coag. factors 5,7,8,9,10,11,12,13 |
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liver is one of the major route to excrete
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Calcium into the bile to the feces
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