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315 Cards in this Set

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Define digestion

The process of conversion of complex food substances to simple absorbable forms is called digestion.

Digestion is carried out by ____________ and ___________ methods

Mechanical and biochemical

Define Nutrition

Process by which food is obtained or synthesized and used to promote body functions like growth, repair and energy.

Nutrition is divided into _________ phases. They are :

Five


Ingestion, Digestion, Absorption, Assimilation, Egestion (IDAAE)

Biomolecules carried by


1. Blood


2. Lymph

1. Glucose and Amino acids


2. Fatty acids and Glycerol

1. Glucose


2. Amino acids


3. Fatty acids


4. Glycerol


These are carried through -

1., 2. Blood


3., 4. Lymph

Define nutrients

Nutrients are substances which provide energy, regulate growth and development and normal functioning of the body

Food substances include following nutrients -

Water, Proteins, Fats, Minerals, Vitamins, Water, Roughage

Types of nutrients with meaning and examples

1. Macronutrients - Required in large quantities - Carbohydrates, Proteins, Fats and water


2. Micronutrients - Required in small quantities - Minerals, vitamins and roughage

Minerals are ____________ substances from sources like ______________, etc.

Inorganic; Common salt, sea foods, leafy vegetables

Who discovered and named vitamins?

Dr. Casimir Funk

Why are vitamins named so?

They are vital amines required for vital life activities

Vitamins are _____________ compounds regularly required in minutes quantities in diet for _____________.

Organic; Normal metabolism, health and growth

Classification of vitamins and examples

1. Fat soluble : Vit. A, D, E, K i.e KEDA (कीडा)


2. Water soluble: Vit B-complex, C

Which nutrients if in excess are not stored in body?

Water and water soluble subs. i.e.


1. Water


2. Proteins (Amino acids)


3. Water soluble vitamins

Human body contains _____% of water (_________% of body weight)

65%, 60-80℅

_____________ keeps protoplasm active.

Water

Water acts as an important ___________ for organic and inorganic nutrients.

Solvent

Water acts as an important solvent for many _______________ reactions

Organic and inorganic

_____________ is essential for various metabolic activities of the body.

Water

_____________ helps in transportation of useful substances.

Water (blood)

_____________ helps in removal of waste materials.

Water (urine)

Water helps in ___________ through sweat.

Thermoregulation

_____________ is required in many enzymatic reactions.

Water

Roughage is digestible/ indigestible?

Indigestible

Roughage consists of ______________.

Cellulose fibres

Use of Roughage

Stimulates intestine, induces peristalsis, maintains proper bowel movements

Adequate quantity of Roughage in the diet prevents ____________ and other complications arising from it like ______________________.

Constipation;


1. Piles/ Hemorrhoids 2. Fissures 3. Fistula (due to strain)

Piles is also known as __________.

Hemorrhoids

The best source of Roughage is ______________.

Cabbage

Sources of Roughage

Leafy vegetables and


Fruits like GOT (tomato, guava, oranges)

Define balanced diet

Diet which contains all nutrients in proper proportion

Give the percent composition of nutrients in a balanced diet

60-70% Carbohydrates, 20-30% Fats, 10-20% proteins

Food should include ____________ for a proper diets. (Names of food)

Cereals, pulses, meat, fish, eggs, fresh vegetables and fruits

A balanced diet provides enough energy in the form of ___________.

Calories

Give daily calories requirement for different types of people

Older - 2500 cal / day


Growing children, young active - 3700 cal / day

What is the protein requirement of an average adult and growing children?

Adult - 1 gram per kg body weight per day


Child - 2 gram per kg body weight per day

Alimentary canal is also called ____________.

Gastrointestinal (GI) tract

Alimentary canal is ___________ long.

8-10 meters

Alimentary canal consists of -

Mouth, Buccal Cavity, pharynx, oesophagus, stomach, small intestine, large intestine, anus

What is mouth?

Anterior-most, transverse slit-like opening of alimentary canal

Mouth leads to ___________ or __________.

Buccal Cavity or oral cavity

Buccal Cavity is lined by _________________. Give reason.

Stratified Squamous.


For protection against pH, mechanical and temperature effect

Buccal Cavity is laterally lines by ____________.

Cheeks

Roof of Buccal Cavity is formed of ______________ .

Palate

Palate is differentiated into __________ and ___________ (name, relative location, and made up of)

1. Hard palate; anterior half; maxillae and Palatine bone


2. Soft palate; posterior half; muscle fibrous connective tissue and mucous epithelium

Floor of Buccal Cavity is occupied by _______________.

Tongue

Mouth is bounded by _____________.

Fleshy upper and lower lips

Buccal Cavity is bounded by ______________ .

Upper and lower jaws bearing teeth

Salivary glands open into the __________.

Mouth

_______________ glands open into the mouth.

Salivary

Part of Buccal Cavity between gums and cheek is the ___________ , while rest is ___________.

Vestibule, oral cavity

Tongue is a ____________, __________ organ.

Voluntary, muscular

Shape of tongue

Roughly triangular

Tongue is attached by its base by _____________ and by ___________ to the floor of the mouth.

Hyoid bone, vestibule

On the upper surface of tongue, numerous projections are present called ____________.

Papillae

Papillae are present on _______________.

Upper surface of tongue

Types of papillae, shape and description

1. Circumvallate - spherical - having taste buds


2. Filiform - hair like projection - no taste buds, but tactile receptors


3. Fungiform - irregular - having tase buds


4. Foliate - leaf like - not in humans

Functions of tongue

1. Mixing food with saliva


2. Deglutition (swallowing)


3. Helps in speech


4. Taste

Swallowing is also known as ______________.

Deglutition

There are total ______ teeth in ____________ of adult human being

32, Buccal cavity

Each tooth has _______ regions

3

Name and describe regions of teeth

Root - embedded in jaw bone


Crown - Visible portion above gums


Neck - Middle part surrounded by gums

Which is the hardest substance of body and why?

Crown, covered by hard coat called enamel

Name and decribe parts of tooth

1. Enamel - hardest substance of human body covering dentine in crown


2. Dentine - Bony part from pulp radiating to enamel


3. Cement - covers root of tooth


4. Periodontal ligament - fibrous cover if cement that fixes tooth to socket (gomphosis joint)


5. Pulp cavity - cavity within dentine containing mass of cells, blood vessels and nerves

Most sensitive part of tooth is ___________. Give reason

Pulp cavity because contains sensitive nerves

Label the parts

From top to bottom


Left - Crown, root


Right - Enamel, Dentine, Pulp, Gums, Bone, Root canal, nerves and blood vessels

Define dentition

Study of teeth with respect to their type, number, arrangement, development is known as dentition

Aspects of study of teeth in dentition

Type, number, arrangement, development (4)

3 donts of Human type with meaning in short

1. Heterodont - different types


2. Diphyodont - two sets


3. Thecodont - Tooth in socket

Types of human teeth with function

1. Heterodont - Cutting


2. Canines - Tearing


3. Premolars - Crushing


4. Molars - Grinding

Dental formulae of humans at different ages

I C PM M


Adults 2 1 2 3


Teens 2 1 2 2


Children 2 1 0 2

Human teeth are __________dont because there are _____ sets of teeth. The first set of ____ teeth is known as _________ or _________ or _________ teeth. Second set of ______ teeth is called ____________ or ____________ dentition.

Diphyodont, 2, 20, milk, deciduous, temporary, 32, adult, permanent

Milk teeth set falls at age of __________.

7-8 years

In human teeth, ____________ are absent

Premolars

Human teeth are embedded in the sockets of ________ and __________.

Maxilla, Mandibles

Buccal Cavity leads to __________ which is common passage for _________.

Oro-pharynx, air and food

____________ and __________ open in pharynx.

Trachea and oesophagus

Anterior end of trachea is called ___________ and anterior end of oesophagus is called ___________.

Glottis, gullet

Glottis is guarded by cartilaginous flap called _____________.

Epiglottis

Function of epiglottis

Prevents entry of food into glottis of respiratory system, when food is swallowed

Epiglottis is usually closed - correct the sentence

False


Epiglottis closes glottis (glottis gets closed) when we swallow, otherwise usually open for breathing

Length of oesophagus

25 cm

Oesophagus starts at ________, passes through __________ (with relative location).

Pharynx, neck behind trachea

Structure of oesophagus below neck

Passes through thoracic cavity, pierces diaphragm and curves upwards before opening into stomach

Oesophagus is made of _____________ and _____________ muscles.

Outer longitudinal, inner circular

Oesophagus is internally lined by _____________, which ____________.

Mucous secreting cells, lubricates passage of food

Which organ of alimentary canal has the thickest muscular layer? Why?

Stomach, maximum peristalsis

Structure and shape of stomach

Bag like, J shaped structure present on left side of the abdomen below diaphragm

Length and orientation of stomach

25 cm, obliquely placed

3 parts of stomach

1. Cardiac


2. Fundus


3. Pyloric stomach / Pylorus

Describe Cardiac

Cardiac is anterior part of stomach into which oesophagus opens

Fundus is also called

Body of stomach

Describe Fundus

The middle part which bulges upwards

Describe pyloric stomach

Narrow posterior part of stomach that opens into duodenum

Opening of stomach in cardiac stomach is guarded by _____________ (with alternate names)

Lower oesophagus/ cardiac/ gastro-oesophageal sphincter

Open of pyloric stomach into duodenum is guarded by ______________.

Pyloric sphincters

Functions of


1. Cardiac sphincter


2. Pyloric sphincter

1. Prevents regurgitation (back flow) of food into Buccal Cavity


2. Regulates passage if food in intestine

Vomiting is due to ____________ of food.

Regurgitation

Dimensions of small intestine

6m long, 2.5 cm broad

The coiled loops of small intestine are held together by _______________ called ______________, supporting ____________.

connective tissue membrane; mesentries; blood vessels, lymph vessels, nerves

Parts of small intestine

Duodenum, Jejunum, Ileum (इलिअम) .... (DJ Ileum)

Location, shape and length of duodenum

Anterior, U shaped, 25 cm long

Location, shape, length and relative broadness of jejunum

Median part of intestine, coiled, 2.5 metres long, narrower tham duodenum

Location, shape, length and relative broadness of jejunum

Posterior part of small intestine, highly coiled, 3.5 metres, little border than jejunum

_______________ opens into large intestine

Ileum

Relative broadness of parts of small intestine

Duodenum > Ileum > Jejunum

Length of large intestine

1.5 metres

Diameter of lumen of large intestine

6.5 cm

Correct the sentence


Diameter of large intestine is 6.5 cm

Diameter of lumen of large intestine is 6.5 cm

What are the parts of large intestine?

Caecum, colon, rectum

Into what is colon differentiated?

Ascending, Transverse, Descending, Sigmoid colon

____________ colon continues to become rectum.

Sigmoid

Colon is internally lined by ____________ for ___________.

Mucous secreting cells, easy passage of food

The junction of Ileum and caecum is known as ___________ having ____________.

Ileocaecal junction, ileocaecal valve

At the junction of Ileum and colon there is _____________. (Structure and name)

Blind pouch named caecum

Caecum hosts some ____________. For example, ___________ live in colon which feed on ________________ and in turn produce _______________.

Symbiotic microbes, E. coli, undigested matter, vitamins B12, B1, B2 and K

Caecum bears a short worm like projection called ____________ which is ____________ in man.

Vermiform appendix, vestigial organ

Appendix is functional in ______________ animals for ____________ as it ______________.

Herbivorous, digestion of cellulose, secretes cellulase

Appendix is functional in ______________ animals for ____________ as it ______________.

Herbivorous, digestion of cellulose, secretes cellulase

Thinnest muscular layer in alimentary canal is found in ____________ for _____________.

Rectum, minimum peristalsis

Rectum opens to exterior through __________.

Anus

Anus is guarded by ____________ which helps in _____________ elimination of undigested matter.

Sphincter, voluntary

Names of digestive glands with macroscopic visibility

1. Salivary


2. Liver


3. Pancreas


4. Gastric


5. Intestinal


1-3 Visible 4,5 - Not Visible

Salivary glands are ___________ types of Glandular glands.

Alveolar, Multicellular

Types of salivary glands with location and number

1. Sublingual - below tongue


2. Submandibular - below lower jaw


3. Parotid - in front of Ear


2 each

The largest salivary glands type is _________.

Parotid glands

Salivary cells secrete __________.

Saliva

Two types of secretory cells in salivary glands with secretion

1. Serous cells - Salivary amylase (ptyalin)


2. Mucous cells - mucous

Saliva also contains lysozyme to ______________.

Cause lysis of ingested bacterial cell wall

Function of saliva

Binds food and makes it slippery so that it can be easily swallowed. (In formation of bolus)

Saliva is secreted due to the stimuli -

1. Smell


2. Sight


3. Thought


4. Touch


Of food

Name the first two largest organs in human body

1st - Skin


2nd - Liver

Which is the largest exocrine gland in body?

Liver

Liver is ___________ in colour, weighing ______ in ______.

Dark reddish brown, 1.5 kg, adults

Location of liver in human body

Below diaphragm on right side

Number, names and relative size lobes of liver

2 lobes


Right lobe - 5/6 of liver


Left lobe - 1/6 of liver

In between two lobes of liver, lies a ________ (shape) like structure called ________.

Sac/bag, gall bladder

Liver is externally covered by ______________ called _____________.

Thin connective tissue layer, Glisson's capsules

Capsule layer enters in liver in form of ____________ and forms ___________.

Septa, lobules

Internally, liver contains many _____________ units called _______________.

Hexagonal, hepatic lobules

In between hepatic lobules is connective tissue containing ______________ and ________________.

Blood vessels, bile ducts

Each hepatic lobule has a ________________ around which are arranged _______________.

central vein, single rows of hepatic cords.

Hepatic cords are made of _____________.

Hepatic cells.

Hepatic cells are polygonal cells with ______________ cytoplasm which stores ____________ and ___________.

distinct nuclei and granular, glycogen, fat droplets

Hepatic cells are hexagonal in shape - True or False giving reason

False. Hepatic cells are polygonal in shape

Hepatic cells secrete _____________ which is collected by ______________ which carries it to _______________.

Bile, bile capillary, bile duct

Bile duct opens into ____________ which deposits bile into gall bladder.

Hepatic duct

Hepatic cords enclose ______________ blood vessels called _____________.

Large irregular, Sinusoids

Sinusoids are surrounded by __________________. What is their function?

Amoeboid/ Kuppfer cells


Function - they are phagocytic. Remove toxins from blood and destroy dead RBCs

Duct from gall bladder is known as ______________.

Cystic duct

Cystic and hepatic duct unite to form ___________

Common hepatic duct

Common hepatic duct and pancreatic duct unite to form ___________.

Hepato-pancreatic duct / ampulla of Vater

Opening of ampulla of Vater into _____________ is guarded by ______________.

Duodenum, sphincter of Oddi

4 names of scientists related to liver

Glisson, Kuppfer, Vater, Oddi

Bile helps in _____________ of Fats.

Emulsification

Liver synthesizes Vitamin ____.

A

Liver stores -

1. Excess glucose in form of glycogen


2. Fat


3. Vitamins A,D,E,K,B12


4. Iron

In liver, ________ of amino acids are _________ to form __________.

Excess, deaminated, urea

Excess of amino acids are deaminated in _____________.

Liver

Precursors for thrombin and fibrin

Prothrombin, Fibrinogen

____________ proteins like ___________ are formed in Liver.

Plasma, Prothrombin, Fibrinogen, Heparin

Classify as Coagulant or Anticoagulant


Thrombin, Fibrin, Heparin

Thrombin, Fibrin - Coagulant


Heparin - Anticoagulant

Bile neutralizes -

Toxic substances (drugs and alcohols), HCl of chyme

Liver produces RBCs in ___________ and destroys RBCs in ___________.

Early foetal stage, adults

Formation of blood is known as ____________.

Haemopoiesis/ Hematopoiesis

Liver and spleen are red coloured due to __________

RBCs

RBCs destroy RBCs and convert _____________ into ____________ and ____________ which give _________ color to bile.

Haemoglobin, Bilirubin, Biliverdin, yellow

The _____________ refers to the liver, gall bladder and bile ducts, and how they work together to make, store and secrete bile.

Biliary tree

Name the following disorders of liver


1. Inflammation


2. Increase in size


3. Very very high fat


4. Shrunken size

1. Hepatitis


2. Hepatomegaly


3. Fatty Liver


4. Liver cirrhosis

Pancreas is a ____________ type of gland.

Tubulo-alveolar heterocrine

Structure, shape and location of pancreas

Lobed, leaf shaped, in loop of duodenum

Two parts of Pancreas with percent

Endocrine (99%) and exocrine (1%)

Exocrine part of pancreas is made of structures called ___________ or _________. They are __________ shaped.

Follicles, Acini, flask

Acini are made up of _______________ , which are __________ (type) and ___________ in shape.

Follicular cells, Glandular, pyramidal

Follicular cells of pancreas rest on _____________ and enclose cavity called ___________.

Basement membrane, lumen

Acini produce ______________.

Pancreatic juice

Location of endocrine part of pancreas

In between Acini

Types of endocrine cells of pancreas with secretion and it's effect

1. Alpha - Glucagon - ⬆️Blood sugar lvl.


2. Beta - Insulin - ⬇️Blood sugar lvl.


3. Delta - Somatostatin - Control on Glucagon or Insulin by inhibition

Other constituents of pancreas excepts the secretory cells

Endocrine and exocrine parts are held together by connective tissue. Also found are blood capillaries and nerve endings

Mention the layers of stomach

From outer to inner


Serosa, Muscularis, Submucosa, Mucosa Muscularis, Mucosa

Which tissue layer is spongy?

Sub-mucosa

Structure and function of serosa

Outermost single layer of Squamous epithelial cells with thin layer of connective tissue


Function: Outermost protective layer

Serosa is made up mostly of which type of tissue?

Single layer of Squamous epithelial cells

Oblique muscles are only found in _____________ for __________.

Stomach, churning

Sub- layers of Muscularis

Outer longitudinal, Middle circular, Inner oblique

Thickest sub layer of Muscularis of stomach

Oblique muscles

Where are Auerbach's and Meissner's plexa found?

Auerbach's - Stomach - between longitudinal and circular muscles of Muscularis


Meissner's - Intestine - in connective tissue between Mucosa and muscularis

Other name of Auerbach's plexus?

Myenteric plexus

What is a plexus?

Network of neurons and ANS fibres in between layers of stomach and intestine

What are the names of plexa in the stomach and intestine?

Thickest layer of stomach

Muscularis

Function of sub-mucosa

Contains blood vessels, lymphatics, nerve endings. Supports mucosa

Which layer of stomach is thrown into folds? What are the folds called?

Mucosa, Rugae

Constituents of mucosa -

1. Lining of columnar epithelium forming gastric gland


2. Lamina Propria, a layer of connective tissue containing gastric glands


3. Muscularis mucosa - layer of smooth muscle fibres

Muscularis mucosa is part of _____________.

Stomach/Intestinal Mucosa

Layers of sub-mucosa

Outer longitudinal, Inner circular

What is the layer of connective tissue containing gastric glands?

Lamina Propria

Inner epithelium of stomach forms ___________________.

Walls of depressions (gastric pits)

The walls of depressions (______________) in stomach form _______________.

Gastric pits, gastric glands

Gastric glands are _______________ structures. They are closely set and embedded ______________ in _____________.

Simple, tubular, vertically, sub-mucosa

Gastric glands are (open/closed) on surface of mucosa.

Open

Parts and description of parts of gastric gland

1. Neck - Narrow consisting of tall cells


2. Body - Oval consisting of cubical cells

Types of cells in walls of gastric glands with function

1. Mucus secretary - secrete mucous


2. Chief/ peptic/ zymogen cells - secrete pepsinogen, prorennin, small amounts of gastric amylase and gastric lipase


3. Parietal/ Oxyntic - large oval cells bulging out of mucous membrane. Secrete HCl and Castle's


Castle's Intrinsic factor


4. Gastrin/ G cells - located in pyloric antrum - secrete gastrin


5. Argentaffin cells - located at base of glands and secrete serotonin (vasoconstrictor)

Other names for chief cells

Peptic/Zymogen cells

Function of Intrinsic factor

Absorption of Vit. B12

Layers of intestine

From outer to inner Serosa, Muscularis, Submucosa, outer rilsdio

Mucous of intestine is thrown into _____________ folds which extend into _____________.

Circular, submucosa

Each fold of intestinal mucosa is thrown into Number of ___________ called _______.

Finger like projection, Villi

The core of each villus is made up of ________________ called _____________ containing _______________.

Connective tissue, tunica propria, blood capillaries and lymph vessels

The epithelial cells of mucosa (except goblet cells) show _____________ of numerous ______________.

Striated/ brush border, microvilli

All epithelial cells of mucosa show brush border - True or False giving reason

False - The epithelial cells of mucosa (except goblet cells) show brush border

Use of microvilli?

Increase surface area

Villi are supplied with _____________ and _____________ called ____________.

Network of capillaries, large lymph vessels, lymph lacteal

Color of lymph lacteal

Yellow

Internal surface area of intestine is greatly increased by ____________, ____________ and _____________ which is essential for _____________.

Mucosal folds, villi, microvilli, absorption

Location of intestinal glands

At intervals between villi

Mucus is also known as ___________.

Mucin

Types of intestinal glands with glandular structure and extent

1. Crypts of Lieberkuhn - Simple tubular - extend into tunica propria upto Muscularis mucosa


2. Brunner's Gland - compound tubular glands as large grape like structures - extend upto sub-mucosa

Types of cells lining crypts of Lieberkuhn with function

1. Striated columnar epithelial cells - Absorption


2. Goblet cells - secrete mucus


3. Paneth cells - secrete digestive enzymes and lysozyme


4. Argentaffin cells - secrete hormones like secretin, cholecystokinin

Describe secretion of Brunner's gland

Alkaline water fluid containing mucin and some enzymes

Location of Brunner's glands

Duodenum ONLY

Secretion of Crypts of Lieberkuhn and Brunner's Gland together form the ________________.

Intestinal juice or succus entericus

What stimulate Brunner's Gland for secretion?

Vagus nerve and secretin

Vagus nerve is ____________ nerve (number and type of nerve)

10th cranial

What protect intestinal mucosa from acid as well as provide alkaline medium for enzyme activities?

Pancreas - 1. Mucus 2. HCO3 minus


Brunner's Gland

Brunner's Gland is also known as

Sub- mucosal Gland

Two types of digestion with meaning

1. Physical / Mechanical - Large size to small size by mastication, churning


2. Chemical - Large to small molecular dimensions by action of enzymes

Mastication is done in _____________.

Oral cavity

Two major functions of Buccal cavity

1. Mastication of food


2. Facilitation of swallowing

The ____________ with help of ____________ masticate and mix up food thoroughly.

Teeth and tongue, saliva

Mucus in saliva helps in _______________ and ______________ the masticated food particles.

Lubricating and swallowing

After mastication, ______________ is then conveyed into pharynx and them oesophagus.

Bolus

Mechanism of swallowing

Action of tongue - Presses against palate - bolus pushed downward into oesophagus through pharynx

Composition of Saliva

1. Salivary amylase (ptyalin)


2. Electrolytes (Na+, K+, Cl-, HCO3-)


3. Lysozyme

Function of saliva w.r.t. bicarbonate

Bicarbonates in saliva neutralize acids in food

Action of salivary amylase

Converts 30% starch into simpler soluble disaccharide sugar - maltose in 6.8 acidic pH

Percentage starch hydrolysed in mouth

30%

pH required for action of ptyalin

6.8 acidic

When are we aware of our food?

When it is in mouth cavity until we swallow it

Meaning of Peristalsis

Successive waves of contraction and relaxation

Secretion of stomach is promoted by hormone __________ and controlled by ___________.

Gastrin; sight, smell, taste of food

Secretion of stomach is ____________ by hormone gastrin and ____________ by sight, smell, taste of food.

promoted, controlled

When does pyloric sphincter open?

When acidity of food reaches a certain level

What is chyme?

Food mixed thoroughly with gastric juice by churning movement

Composition of gastric juice

Mucous, pepsinogen, rennin, 0.5% (percentage in gastric juice not concentration) mucus

Stomach stores food for ___________

4-5 hours

____________ and __________ present in the gastric juice play an important role in lubrication and protection of the mucosal epithelium from excoriation by the highly concentrated hydrochloric acid.

Mucus, bicarbonates

function of mucus and bicarbonates in stomach

Lubrication and protection of the mucosal epithelium from excoriation by the highly concentrated hydrochloric acid

Lipases are secreted by __________.

Mainly PANCREAS, but also STOMACH in small amounts

Functions of HCl in stomach (6)

1. Kills bacteria


2. Dissolves mineral salts


3. Decalcifies bones


4. Acidic pH (1.8) optimal for pepsin


5. Softens food


6. Stop action of salivary amylase

Which nutrient(s) are not digested in stomach?

Carbohydrates

Which is the proteolytic enzyme of stomach?

Pepsin

Formation of pepsin

Proenzyme pepsinogen on exposure to HCl gets converted to active enzyme pepsin

Action of pepsin

Pepsin/ Acidic Med.


Proteins --------------------------> Proteoses + Peptones

Proteoses and Peptones are

Peptides

Name a gastric enzyme which is more active in adults? State it's action

Rennin (check spelling, it's not renin)


Converts casein in milk into paracasein


Rennin/ Acidic Med.


Casein -------------------------> Paracasein

Paracasein is further digested by _____________.

Pepsin

Fate of casein in adults

Usually not utilized

Components of Pancreatic juice

1. Trypsinogen


2. Chymotrypsinogen


3. Procarboxypeptidase


4. Pancreatic amylase/ Amylopsin


5. Pancreatic Lipase/ Steapsin


6. Nuclease

Trypsin is activated into ______________ by _____________.

Trypsin, Enterokinase

Functions of trypsin

1. Proteins, Proteoses, Peptones to polypeptides


2. Chymotrypsinogen to chymotrypsin


3. Procarboxypeptidase to Carboxypeptidase

Erypsin is a ______________.

Dipeptidase

Mechanism of digestion of proteins in intestine

A

Mechanism of digestion of carbohydrates in intestine

A

Mechanism of digestion of fats in intestine

A

Mechanism of digestion of nucleic acids in intestine

A

Digestion of nutrients completed in _________________

Duodenum

Acidity of food stimulates mucosa of ____________ to secrete hormones

Duodenum

Color of bile

Yellowish green

Enzymes in bile.

Nil. It is devoid of enzymes.

Composition of bile

Bile pigments, H2O, cholesterol, phospholipids, bile salts

Function of bile salts

Help in breaking down oil droplets into small globules/ micelles forming milky emulsion (emulsification) to facilitate further digestion of fats

Names and function of Bile pigments

Bilirubin, Biliverdin


Give colour to faeces and urine

2 most important functions of bile

1. Activates lipases


2. Neutralizes acidic chyme

How do Bilirubin and Biliverdin give colour to faeces and urine?

They decompose into stercobilin and urobilin- urochrome


1. Bilirubin - Stercobilin - Not absorbable - colour to faeces


2. Biliverdin - Urobilin/ urochrome - Absorbable - colour to urine

Food is completely digested in duodenum into __________ form called ___________, which is further subjected to ______________.

Liquid, chyle, absorption

Other names for pancreatic amylase and pancreatic lipase resp.

Amylopsin and Steapsin resp.

Other name for Amylopsin and Steapsin resp.

Pancreatic amylase and pancreatic lipase resp.

Major absorption occurs in _______________.

Jejunum

Substances absorbed by


1. Simple diffusion


2. Facilitated diffusion


3. Active transport

1. Glucose , some amino acids, some electrolytes (3)


2. Fructose, some amino acids (2)


3. Amino acids, monosaccharides like glucose, electrolytes like Na+ (3)

Simple substances are absorbed in _____________ and _____________.

Jejunum, Ileum

Transport of water depends on _________________.

Concentration gradient

Egestion is caused by ________________.

Mass peristaltic movement

Enterokinase is secreted by ______________.

Intestinal mucosa

Function of ileocaecal valve

Prevent back flow of faecal matter into small intestine

Function of ileocaecal valve

Prevent back flow of faecal matter into small intestine

B

pH in intestine

Alkaline 8.4

Names of bile salts

Sodium bicarbonate, sodium glycocholate, sodium taurocholate

Nucleotidases are also known as _________________

Nucleophosphatases

Mention which part of villus absorbs the following


1. Simple sugars


2. Amino acids


3. Fatty acids


4. Glycerol

1, 2 - Blood vessels


3, 4 - Lymph lacteals

Why cannot fatty acids and glycerol be absorbed by blood?

They are water insoluble

How can fatty acids and glycerol absorbed?

1. Incorporated into small droplets called micelles


2. Move into intestinal mucosa


3. Reformed into very small protein coated fat globules called chylomicrons


4. Transported to lymph lacteals


5. Release into blood stream

Mention the substances absorbed by -


1. Mouth


2. Stomach


3. Small Intestine


4. Large intestine

1. Drugs in contact with mouth mucosa and lower side of tongue


2. Water, simple sugars, alcohol, aspirin, lipid soluble drugs


3. Principal organ - All


4. Water, minerals, drugs

Brown colour of faeces is due to -

Stercobilinogen, Stercobilin

Foul smell or faeces is due to -

Indole, Sagale, H2S

In large intestine, secretion of ___________ helps in --

Mucus, adhering waste undigested particles together and lubricating of easy passage

Hormones of Gastrointestinal Tract

1. Gastrin 2. Secretin 3. Pancreozymin 4. Cholecystokinin (CCK) 5. Enterogasteron/ Gastric Inhibitory Polypeptide (GIP) 6. Duocrinin 7. Enterokinin 8. Vilikinin

Sources of -


1. Gastrin 2. Secretin 3. Pancreozymin 4. Cholecystokinin (CCK) 5. Enterogasteron/ Gastric Inhibitory Polypeptide (GIP) 6. Duocrinin 7. Enterokinin 8. Vilikinin

1. G/ Argentaffin cells of pyloric gastric glands 2. S cells of duodenum and Jejunum 3. Duodenum 4. I cells of duodenum 5,6. Duodenum 7,8. Small intestine

Effect of gastrin

⬆️️ HCl, Pepsinogen, Prorennin, cardiac and pyloric sphincter movement


Stimulates stomach emptying

Effect of secretin

Stimulates release of NaHCO3 fluid from pancreas and liver

Pancreozymin

️ Pancreatic juice

Effect of CCK

Stimulates gall bladder cont. to release bile


Relax sphincter of Oddi


⬆️Bile secretion

Effect of GIP

Inhibit gastrin (Opp effects)

Effect of Duocrinin

️ mucus from Brunner's gland

Effect of Enterokinin

️ intestinal enzymes by crypts

Effect of vilikinin

⬆️ Movement of villi for ⬆️ absorption

Define gross calorific value. Give its unit

The amount of heat liberated by complete combustion of 1 gram food in a Bomb calorimeter is termed as gross calorific value.


Kcal/g

Define physiological value of food

The actual energy produced by 1 gram of food is its physiological value

Give the gross calorific value and physiological value of fats, proteins, and carbohydrates

Food - Gross calorific - Physiological


Fats - 9.45 - 9.0


Protein - 5.65 - 4.0


Carbohydrates - 4.1 - 4.0

Kwashiorkor is seen in ______________.

Infants and children between 1 to 3 years of age

Nutritional deficiency diseases are caused due to _______________.

Lack of Proteins, vitamins, minerals in diet

Basic causes of Kwashiorkor

Ignorance, poverty, infectious diseases like intestinal diseases, respiratory infection, Measles, diarrhoea, etc

Vomit centre is at _____________.

Centre of medulla