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7 Cards in this Set

  • Front
  • Back
Chemical breakdown of food by enzymes secreted by....
glangular cells of mouth
Chief cells in stomach
Exocrine cells of pancreas
Two types of digestion...
Cavital digestion-enzymes secreted by salivary glands, stomach and pancreas

Membrane digestion- hydrolysisng enzymes associated with SI brush border
Movement of nutrients from lumen into blood is restricted by pathway, consisting of...
Unstirred aqueous layer
Glycocalyx "fuzzy coat"
Cell membrane
Cyoplasm of cell
Basal/lateral memebrane of cell
intracellular space
basement membrane
Lymph/blood vessel
Transport process...
Pinocytosis- base of microvilli

Passive diffusion- through intracellular spaces or pores in cell membrane

Facilitated Diffusion

Active transport
CHO digestion, which contributes to 50% of our calorie intake, comprises of the following...
Salivary amylase- 6.5-7.5 pH, parotid and submandibular glands, breaks down polysaccharides to di- and tri-saccharides, is rendered inactive after 2 hour digestion

Duodenum- pancreatic Alpha amylase- breaks down any remaining plysach's to tri and di, but does NOT fully hydrolises di and tri to monosaccharrides

Intestinal Muscosa- Sucrase- sucrose to glucose and fructose, Lactase- lactose to galactose and glucost, Maltase-maltose to 2x glucose. Polysaccharides-staarch amylose and amylopectin consist of 1-4 and 1-4 alpha bonds-however, amalyse can only digest 1-4 A bonds- breaks it down to aplpha limit dextrins, maltose and maltatriose-> A.L.D- hydrolised 5% glucoamaylase, 95% isomaltose, Maltose/maltatriose-25% glucoamaylase, 25% sucrase, 50% isomaltase
CHO absorption consists of both active and passive diffusion...
aqueous channels between enthrocytes and pores between brush border membranes- fructose

Membrane carrier system (NA+ dependent)-> owing to larger hexoses unable to fit through aqueous channels/pores-glucose/galactose
CHO secondary active transport...
2 NA+ fpr each glucose molecule, NA-K ATPase maintains an NA gradient which facilitates glucose absorption. (Na exits cell and K enters (3 NA for 2 K)

Na facilitated diffusion of glucose. Exit of glucose from basal lateral membrane is achieved by diffusion or Na independent carrier of glucose