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45 Cards in this Set
- Front
- Back
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Neutral stain |
Romanowsky stain |
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What color is the structure when it is basic |
Red |
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What color is the structure when it is acidic |
Blue |
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Cell renewal system in which cell production equals cell death |
Granulocytopoiesis |
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Compartments of bone marrow |
1 stem cell pool 2 differential prolifirating pool 3 nonproliferating (maaturaion) pool |
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-not self sustaining -Consist of large and small myelocytes -division occurs -DNA synthesis occurs |
DIfferential proliferating pool
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Self sustaining -generic sources of cells - |
Stem cell pool |
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Not self sustaining -has no DNA synthesis -biocheical and morphological changes occur in nucleus |
Non proliferating pool |
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CGP- present along the circulation |
Circulatory granulocyte pool |
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MGP- attachd on the wall of vessels |
Marginal Granulocyte pool |
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TBGP- sum of all CGP and MGP leukocytes |
Total Blood granulocyte pool |
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Stimulates th drop of MGP |
Epinephrine and exercise |
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a laboratory procedure in which white blood cells are separated from a sample of blood. |
Leukapheresis |
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Increases capillary cell permeabilty and induce local migration of granulocyte |
Leukotaxine |
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Life span of lymphocytes |
3 to 4 days (Sin men sometimes 20yrs) |
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Where does short lived lymphocytes are |
Bone marrow |
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Where does long lived lymphocytes are |
Thoracic duct |
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Antigen recognition and cell mediated response |
T cells |
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Precursors for antibody producing cells |
B cells |
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Where T cells produce |
Thymus |
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Where B cells produce |
Bursa in chicken Equivalent bursa-dependent in mammals (bone marrow) |
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Responsibe for physiological neutrophilia and leukocytosis |
Epinephrine |
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Blocks the receptor on endothelial cells preventing blood lymphocytes from entering lymphoid tissue |
Epinephrine |
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Species characteristics that is normal physiological neutrophilia |
Uncommon in dogs Common in healthy cats In healthy cattle during parturition and exercise Common in healthy young horse In lactating sows and pig 3-5 hrs after feeding Common in birds |
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Largest organ of the body
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Skin
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Lymphoid
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Lymphocytes
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Myeloid
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Granulocytes Rbc Platelets Wbc |
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nucleus of neutrophil
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polymorphonuclear
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functions of neutrophils |
adherens and emigration through vessel walls - chemotaxis - ingestion and degranulation - bactericidal |
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Neutrophils of birds
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Heterophils |
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T-F Heterophils have dull red cytoplasmic granulation, and they lack myelo peroxidase activity and have larger and more electrons |
true |
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microbiocidal elements of heterophil |
lactoferin |
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enzyme of heterophil
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collagenase |
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Functions of eosinophils |
- attach to and kill helminths mediated with antibodies and T lymphocytes perforins - may suppress hyper sensitivity reactions by inhibiting chemical mediators release by mast cells during allergic and anaphylactic reactions - may promote inflammation by binding with IgE and become activated releasing their granule which contribute to tissue damage and allergic reactions -Phagocytic slightly bactericidal |
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Functions of basophils
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-Participate in immidiate and delaying hypersensitivity reaction by releasing histamine - promotion of lipid metabolism by activation of lipoprotein lipase -Prevention and promotion hemostasis -rejection of parasite such as ticks -possible tumor cell toxicity |
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Description of basophil
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Ribbon like nucleus - avian and reptile has round nucleus |
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Neutrophil lysosome |
-Myelo peroxidase -elastase -esterase |
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Eosinophil lysosome |
Hydrolase - Major basic protein - eosinophil specific peroxidase |
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Basophil lysosome |
Histamine -Heparin -Mucopolysaccharide -Lacks hydrolase |
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Monocyte lysosomes |
-Peroxidase -hydrolase |
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Posses pseudopodia hairlike processes in plasma membrane Blue-grey cytoplasm Pink lysosome granules? |
Monocyte
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examples of monocyte derived macrophage
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Histiocytes - plural and peritonial macrophage - pulmunary alveolar macrophage - macrophage of spleen lymphnode and bone marrow - kupffer cells - Microglial |
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Function of macrophage |
Phagocytise and digest foreign materials and dead cells -Major source of csf and cytokines -Secrete chemotactic substance and plasminogen - pinocytotic and catabolize protein serum |
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lymphocytes of dog (sometimes cats and horse) |
red lymphocytes |
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function of lymphocytes |
-Anti body production -Macrophage and T lymphocytes regulate antibody production -secretes interleukins, cytokines and lymphokines -some are cytotoxic for virus infected cell |
