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30 Cards in this Set
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Reduction in the number of rbc, hemoglobin or both in the circulating blood |
Anemia |
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Anemia may be associated with |
-Decreased rbc production -inappropriate rbc loss -increase rbc destruction |
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Basis of morphological classification |
MCV MCHC MCH |
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Average mass of hemoglobin per rbc in a sample of blood |
MCH |
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Measure of concentration of hemoglobin in a given volume of packed rbc. Defined as ratio of weight of hemoglobin to volume of rbc |
MCHC |
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Depression of erythrogenesis |
Normocytic, normochromic |
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Dietary deficiency |
Macrocytic, Normochromic |
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Recovery from large loss of RBC |
Macrocytic, hypochromic |
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Iron deficiency |
Microcytic, hypochromic |
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Follows trauma or surgical procedure, sweet clover, warfarin, or bracken fern |
Acute hemorrhage |
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Anemia manifested immediately until blood volume returns to normal |
Peracute hemorrhage |
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Usually microcytic and hypochromic due to depletion of iron; parasitism, git lesions, bleeding into body cavities |
Chronic hemorrhage |
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Examples of blood loss anemia |
Acute hemorrhage Peracute hemorrhage Chromic hemorrhage |
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Blood parasites: |
Anaplasma Piroplasma Haemobartonella Eperythrozoon |
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Viral infections: |
EIA |
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Bacterial infections: |
C. Haemolyticum Leptospira icterohaemorrhagiae |
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Poisonous plants: |
Castor bean Oak shoot Wild onions |
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Chemical agents: |
Copper Lead Phenothiazine Methylene blue |
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Metabolic diseases |
-Immunohemolytic ds. Of newborn -autoimmune hemolytic anemia |
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Increase erythrogenesis in response to anemic process, high porphyrin induces defect in synthesis of heme, rbc defective and susceptible to hemolysis |
Porphyria in cattle |
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Severe anemia due to hemolysis or hemorrhage (def in pyruvate kinase-energy metabolism) -with remarkable nucleated rbc, reticulocytes, polychromasia, anisocytosis, poikilocytosis |
Familial anemia im Basenji dogs |
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Stomatocytosis |
Hemolytic anemia in chondrodysplastic malamute |
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Is irregular clump of ribosomal RNA and organelles like mitochondria |
Reticulum |
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Irregular net-like structures in polychromatoohils |
Reticulocytes |
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Decreased production of rbc caused vy inadequate production of RBC by the bone marrow |
Non regenerative anemia |
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Species where reticulocytes when stained with new methylene blue AGGREGATES ONLY |
Canine |
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Average size/volume of rbc |
MCV |
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MCV means |
Mean corpuscular volume |
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MCH means |
Mean corpuscular hemoglobin |
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MCHC means |
Mean corpuscular hemoglobin concentration |