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143 Cards in this Set

  • Front
  • Back

3 Tunics of blood vessel wall

Tunica intima


Tunica media


Tunica externa

Simple squamous enodthelium continuous with endocardium

Tunica intima (interna)

Lines ventricles and covers valves

endocardium

True or false


it is important for tunica intima to have a smooth friction free surface.

True

Mostly circular smooth muscle with sympathetic innervation

Tunica media

do veins or arteris have a thicker tunica media

arteries

The amount of blood output depends on the ___________ or _________ of the tunica __________.

Vasoconstriction


Vasodilation


Media

Outermost CT layer that structurally supports the wall. It keeps things in place like netting (2 names)

Tunica externa (adventitia)

Do veins or arteries have more tunica externa?

Veins

opening where blood flows

Lumen

________ of total blood volume is in the venus system

2/3

Transport blood away from the heart

arteries

2 kinds of arteries

Elastic


Muscular

Arteries with the thickest walls, largest diameter, close to heart

Elastic arteries

why are elastic arteries called conducting arteries

because they conduct blood to the muscular arteries

Examples of elastic arteries

aorta, pulmonary trunk + major branches

Arteries with more elastic CT and less smooth muscle

Elastic arteries

True or False


elastic recoil allows pressure to remain constant

True

Has more smooth muscle in T media than elastic arteries

Muscular arteries

muscular arteries are also known as....

distributing arteries

Arteries that control blood flow to organs

distributing arteries

2 Examples of distributing arteries

Renal, superior mesenteric

smallest of arteries

arterioles

vessels right before capillaries

arterioles

do arterioles have the same three tunics as other arteries?

yes

Smallest of blood vessels

capillaries

Capillaries only have the tunica _________.

Intima

5 tissues that don't have capillaries

tendons


cartilage


ligamants


cornea


sclera

2 types of capillaries

continuous


fenestrated

cells of endothelium joined by tight junctions found in vessels of the skin and muscle

continous capillaries

Windowed capillaries found in areas of high absorption/filtration such as the intestines and the kidneys

fenestrated

encloses entrance to capillary bed regulating the amount of blood flow to capillary beds

pre-capillary sphincter

when would it be good for the pre-capillary sphincter to close?

during a fight/flight response

shunt that bypasses the capillary bed

thoroughfare channel

the vascular shut is made up of what two channels

metarteriole


Thoroughfare channel

Vascular shunt on the arteriole side

Metarteriole

Vascular shunt on venule side

Thoroughfare channel

The venous system has _______ walls compared to arteries

thin

The smallest of veins at the exit of the capillary bed

venules

thinner walls but larger lumen than arteries

Veins

______ % of blood volume is in the venous system at any time

65

Veins are designed to withstand high or low pressure

low

what keeps veins flowing in only one direction?

semilunar like valves

which tunica is the heaviest in veins

tunica externa

Which tunica is the smallest in veins

tunica media

more than one pathway through an area

vascular anastomoses

collateral channels feeding an area just incase one becomes clogged

arterial anastomose

thoroughfare channels (metarteriole) between arteriol and venule

Arteriovenous anastomoses

very extensive with a big lumen so rarely blocked pathway through an area with

Venous anastomoses

the blood volume flowing through any area (perfusion)

blood flow

force exerted against inner walls (expressed in mm Hg)

Blood pressure

opposition to flow - slowing of flow

peripheral resistance

three things that effect peripheral resistance

viscosity


vessel length


Diameter

how does viscosity effect peripheral resistance

an increase in viscosity will lead to an increase in peripheral resistance

How does vessel length effect peripheral resistance

to increase length slows the flow of blood as it goes therefore increasing peripheral resistance

how does the diameter of vessel effect the peripheral resistance

a decrease in diameter will result in increasing P.R.

What regulates the diameter of a vessel
sympathetic N.S.

Systolic blood pressure occurs during _____________ ____________

ventricular systole

What is it called when blood is moving into the arteriol system via the aorta

ventricular systole

average systolic BP

120 mm hg

_______ ______ is measured during ventricular diastole

Diastolic BP

Semilunars are still closed but blood is still flowing in the arteriole system because of residual pressure (ballooning of the aorta)

Diastolic BP

what is the average Diastolic BP

70-80 mm hg

Formula for pulse pressure

Systolic pressure - diastolic pressure




ex 40=120-80

measure of average blood flow moving thru the arterial system (how fast blood moves thru the system)

Mean arterial pressure

Formula for Mean arterial pressure

MAP=diastolic + 1/3 pulse pressure




MAP = 80 + 1/3(40)


MAP = 93 mm hg

When measuring MAP the further from the heart the _______ the number

lower

what is the measurement of capillary blood pressure

25mm Hg at the arteriole end and 15 mm Hg at the venule end

what is the measurement of venous blood pressure

15mm Hg dropping to 0 mm Hg at the right atrium

2 factor aiding venous return

Respiratory pump


Muscular pump

inhaling will squeeze abdominal veins increasing intrabdominal pressure milking blood back to the heart - vacuum in thorax sucks blood back to the heart

respiratory pump

Skeletal muscle squeezes veins milking blood back to the heart

muscular pump

3 factors affecting blood pressure

Cardiac output


Peripheral resistance


Blood volume

an increase in cardia output (pumping faster) will cause a/n _________ in blood pressure

increase

an increase in peripheral resistance (decrease in BV diameter) will __________ blood pressure

increase

Double the radius of BV will ________ peripheral resistance or ___________ blood flow by 16x

decrease


increase

Increasing blood volume will ______________ blood pressure

increase

how does salt effect BP?

increase

why does salt increase BP

because salt cause you to retain water increasing blood volume

Regulating blood pressure is done by....

Changing arteriole (smallest but most numerous arteries) diameter to alter blood distribution and maintain sufficient blood pressure

5 Nervous system controls for regulating BP

Vasomotor center


Vasomotor fibers


Baroreceptors


Chemoreceptors


Higher brain centers

The ________ ___________ releases a constant stream impulses to make vasoconstriction happen

medulla oblongata

Constant partial arteriole vasoconstriction

Vasomotor tone

Sympathetic efferents that innervate arteriole tunica media smooth muscle

Vasomotor fibers (neurons)

Vasomotor fibers release __________ causing constriction

nor epi

mechanoreceptor located in the aortic arch and carotid sinus

Baroreceptors

Responds to mechanical deformation

Baroreceptors (mechanoreceptors)

located in the carotid and aorta, respond to O2 and CO2/pH

Chemoreceptors

Controls sympathetic (fight/flight) impulses to medulla oblongata

hypothalamus

3 hormonal controls regulating BP

Adrenal medulla hormones


Angiotensin II


Atrial natriuretuc peptide (ANP)

2 types of adrenal medulla hormones

Norepinephrine


Epinephrine

adrenal hormone that causes vasoconstriction

nor epi

adrenal hormone that causes vasoconstriction (except in skeletal muscle blood vessels )

Epi

Adrenal hormone that acts as a potent vasoconstrictor which also cause release of aldosterone and ADH

Angiotensin II

Causes kidneys to retain sodium and water

aldosterone

posterior pituitary hormone that causes kidneys to reatain H20

antidiuretic hormone

hormone diuretic that causes decrease fluid volume (Na+ and H2O) leading to decrease in BP

Atrial natriuretic peptide (ANP)

Do hormones have a short or longterm effect on regulating BP

short term - mainly control ventilation not vessels

Longterm effect on regulating BP

Renal (kidney) control

Direct renal control of BP

retain or lose fluid to control BP by controlling urine output

Indirect renal control of BP

hormonal mechanism

Causes alsoterone and ADH release

Renin-angiotensin-aldosterone system

Kidneys release ____________ ultimately cause the formation of angiotensin II

renin

Blood flow:


_____% to brain


_____% to heart


_____% to kidneys


_____% to digestive


_____% to Skeletal muscel

13


4


20


24


20



Velocity of blood flow is


fastest in _______


slowest in __________


and speeds up in _______

aorta


capillaries


veins

Velocity is inversely related to total ______-______ _______

cross-sectional area

when is velocity of blood flow the fastest

in area of least total area

area of:


Aorta


Capillaries


IVC

2.5 cm2


2500 cm2


8cm2

list in order of fastest to slowest blood velocity


Aorta


Capillaries


IVC

aorta


IVC


Capillaries

Local regulation of blood flow

autoregulation

organs control their own arteriols to increase or decrease blood blow via autoregulation using speialized control due to local conditions like ________ _______ and ______.

CO2


O2


nutrients

blood flow in ________ ________ varies with activity level

skeletal muscle

at rest ______% of capillaries are open




Nor epi keeps _______% closed

25


75

Blood flow increases in response to local O2 CO2 and metabolic concentrations causing autoregulation to override sympathetic NS

Exercise hyperemia

do not tolerate low O2 levels

neurons in the brain

possesses the most precise autoregulatory system in the body

brain

the most important stimulus for autoregulation

carbon dioxide

the ________ has extensive anastomoses for efficient heat control

skin

__________ stimulation cause vasoconstriction in skin

sympathetic

in the _______ arteries and arterioles are similar to veins of the rest of the body

lungs

Pulmonary pressure is __/___

25/10

contracting ventricles compress coronary BV therefore flow stops to the ________ during ventricular ___________.

heart


systole

the heart has a large amount of ___________ to allow for O2 storage

myoglobin

an _________ in CO2 causes and _________ in vasodilation

increase


increase

blood flow through capillaries

Capillary dynamics

Gas and nutrient exchange happens by _________.

diffusion

In capillary dynamics fluid moves in what 2 ways?

Hydrostatic pressure


Osmotic pressure

filtration pressure... pushing pressure. Blood pressure filters fluid from high to low pressure

Hydrostatic pressure

Based on where particles are due to presence of non diffusible solutes

Osmotic pressure

water is pulled toward the area with the highest or lowest osmotic pressure?

highest

Capillary Hydrostatic Pressure

called filtation pressure... pushing fluid from capillary to interstitial area

what is capillary HP at arteriole end?

25 mm Hg

How much is Hp at venule end?

15 mm Hg

how much is interstitial HP?

-5 (pulling like vacuum)

formula for net hydrostatic pressure

CHP - IHP

Net hydrostatic pressure at arteriole end

25- (-5) = 30 mm Hg

Net hydrostatic pressure at venule end

15 - (-5) = 20 mm Hg

how much is capillary osmotic pressure

25 mm Hg at both ends

how much is interstitial osmotic pressure

3 mm Hg both ends of capillary

what is the formula for net osmotic pressure

capillary osmotic pressure - interstitial osmotic pressure




25 - 3 = 22

Formula for the direction of fluid movements

Net HP - Net OP




(CHP - IHP) - (COP - IOP)

Direction of fluid moving at arteriol end of capillary

(25 - (-5)) - (25-3) = 8 mm Hg net




Fluid moving out

Direction of fluid moving at venule end of capillary

(15-(-5)) - (25-3) = -2 mm Hg




Fluid moving in