Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
143 Cards in this Set
- Front
- Back
3 Tunics of blood vessel wall |
Tunica intima Tunica media Tunica externa |
|
Simple squamous enodthelium continuous with endocardium |
Tunica intima (interna) |
|
Lines ventricles and covers valves |
endocardium |
|
True or false it is important for tunica intima to have a smooth friction free surface. |
True |
|
Mostly circular smooth muscle with sympathetic innervation |
Tunica media |
|
do veins or arteris have a thicker tunica media |
arteries |
|
The amount of blood output depends on the ___________ or _________ of the tunica __________. |
Vasoconstriction Vasodilation Media |
|
Outermost CT layer that structurally supports the wall. It keeps things in place like netting (2 names) |
Tunica externa (adventitia) |
|
Do veins or arteries have more tunica externa? |
Veins |
|
opening where blood flows |
Lumen |
|
________ of total blood volume is in the venus system |
2/3 |
|
Transport blood away from the heart |
arteries |
|
2 kinds of arteries |
Elastic Muscular |
|
Arteries with the thickest walls, largest diameter, close to heart |
Elastic arteries |
|
why are elastic arteries called conducting arteries |
because they conduct blood to the muscular arteries |
|
Examples of elastic arteries |
aorta, pulmonary trunk + major branches |
|
Arteries with more elastic CT and less smooth muscle |
Elastic arteries |
|
True or False elastic recoil allows pressure to remain constant |
True |
|
Has more smooth muscle in T media than elastic arteries |
Muscular arteries |
|
muscular arteries are also known as.... |
distributing arteries |
|
Arteries that control blood flow to organs |
distributing arteries |
|
2 Examples of distributing arteries |
Renal, superior mesenteric |
|
smallest of arteries |
arterioles |
|
vessels right before capillaries |
arterioles |
|
do arterioles have the same three tunics as other arteries? |
yes |
|
Smallest of blood vessels |
capillaries |
|
Capillaries only have the tunica _________. |
Intima |
|
5 tissues that don't have capillaries |
tendons cartilage ligamants cornea sclera |
|
2 types of capillaries |
continuous fenestrated |
|
cells of endothelium joined by tight junctions found in vessels of the skin and muscle |
continous capillaries |
|
Windowed capillaries found in areas of high absorption/filtration such as the intestines and the kidneys |
fenestrated |
|
encloses entrance to capillary bed regulating the amount of blood flow to capillary beds |
pre-capillary sphincter |
|
when would it be good for the pre-capillary sphincter to close? |
during a fight/flight response |
|
shunt that bypasses the capillary bed |
thoroughfare channel |
|
the vascular shut is made up of what two channels |
metarteriole Thoroughfare channel |
|
Vascular shunt on the arteriole side |
Metarteriole |
|
Vascular shunt on venule side |
Thoroughfare channel |
|
The venous system has _______ walls compared to arteries |
thin |
|
The smallest of veins at the exit of the capillary bed |
venules |
|
thinner walls but larger lumen than arteries |
Veins |
|
______ % of blood volume is in the venous system at any time |
65 |
|
Veins are designed to withstand high or low pressure |
low |
|
what keeps veins flowing in only one direction? |
semilunar like valves |
|
which tunica is the heaviest in veins |
tunica externa |
|
Which tunica is the smallest in veins |
tunica media |
|
more than one pathway through an area |
vascular anastomoses |
|
collateral channels feeding an area just incase one becomes clogged |
arterial anastomose |
|
thoroughfare channels (metarteriole) between arteriol and venule |
Arteriovenous anastomoses |
|
very extensive with a big lumen so rarely blocked pathway through an area with |
Venous anastomoses |
|
the blood volume flowing through any area (perfusion) |
blood flow |
|
force exerted against inner walls (expressed in mm Hg) |
Blood pressure |
|
opposition to flow - slowing of flow |
peripheral resistance |
|
three things that effect peripheral resistance |
viscosity vessel length Diameter |
|
how does viscosity effect peripheral resistance |
an increase in viscosity will lead to an increase in peripheral resistance |
|
How does vessel length effect peripheral resistance |
to increase length slows the flow of blood as it goes therefore increasing peripheral resistance |
|
how does the diameter of vessel effect the peripheral resistance |
a decrease in diameter will result in increasing P.R. |
|
What regulates the diameter of a vessel
|
sympathetic N.S.
|
|
Systolic blood pressure occurs during _____________ ____________ |
ventricular systole |
|
What is it called when blood is moving into the arteriol system via the aorta |
ventricular systole |
|
average systolic BP |
120 mm hg |
|
_______ ______ is measured during ventricular diastole |
Diastolic BP |
|
Semilunars are still closed but blood is still flowing in the arteriole system because of residual pressure (ballooning of the aorta) |
Diastolic BP |
|
what is the average Diastolic BP |
70-80 mm hg |
|
Formula for pulse pressure |
Systolic pressure - diastolic pressure ex 40=120-80 |
|
measure of average blood flow moving thru the arterial system (how fast blood moves thru the system) |
Mean arterial pressure |
|
Formula for Mean arterial pressure |
MAP=diastolic + 1/3 pulse pressure MAP = 80 + 1/3(40) MAP = 93 mm hg |
|
When measuring MAP the further from the heart the _______ the number |
lower |
|
what is the measurement of capillary blood pressure |
25mm Hg at the arteriole end and 15 mm Hg at the venule end |
|
what is the measurement of venous blood pressure |
15mm Hg dropping to 0 mm Hg at the right atrium |
|
2 factor aiding venous return |
Respiratory pump Muscular pump |
|
inhaling will squeeze abdominal veins increasing intrabdominal pressure milking blood back to the heart - vacuum in thorax sucks blood back to the heart |
respiratory pump |
|
Skeletal muscle squeezes veins milking blood back to the heart |
muscular pump |
|
3 factors affecting blood pressure |
Cardiac output Peripheral resistance Blood volume |
|
an increase in cardia output (pumping faster) will cause a/n _________ in blood pressure |
increase |
|
an increase in peripheral resistance (decrease in BV diameter) will __________ blood pressure |
increase |
|
Double the radius of BV will ________ peripheral resistance or ___________ blood flow by 16x |
decrease increase |
|
Increasing blood volume will ______________ blood pressure |
increase |
|
how does salt effect BP? |
increase |
|
why does salt increase BP |
because salt cause you to retain water increasing blood volume
|
|
Regulating blood pressure is done by.... |
Changing arteriole (smallest but most numerous arteries) diameter to alter blood distribution and maintain sufficient blood pressure
|
|
5 Nervous system controls for regulating BP |
Vasomotor center Vasomotor fibers Baroreceptors Chemoreceptors Higher brain centers |
|
The ________ ___________ releases a constant stream impulses to make vasoconstriction happen |
medulla oblongata |
|
Constant partial arteriole vasoconstriction |
Vasomotor tone |
|
Sympathetic efferents that innervate arteriole tunica media smooth muscle |
Vasomotor fibers (neurons) |
|
Vasomotor fibers release __________ causing constriction |
nor epi |
|
mechanoreceptor located in the aortic arch and carotid sinus |
Baroreceptors |
|
Responds to mechanical deformation |
Baroreceptors (mechanoreceptors) |
|
located in the carotid and aorta, respond to O2 and CO2/pH |
Chemoreceptors |
|
Controls sympathetic (fight/flight) impulses to medulla oblongata |
hypothalamus |
|
3 hormonal controls regulating BP |
Adrenal medulla hormones Angiotensin II Atrial natriuretuc peptide (ANP) |
|
2 types of adrenal medulla hormones |
Norepinephrine Epinephrine |
|
adrenal hormone that causes vasoconstriction |
nor epi |
|
adrenal hormone that causes vasoconstriction (except in skeletal muscle blood vessels ) |
Epi |
|
Adrenal hormone that acts as a potent vasoconstrictor which also cause release of aldosterone and ADH |
Angiotensin II |
|
Causes kidneys to retain sodium and water |
aldosterone |
|
posterior pituitary hormone that causes kidneys to reatain H20 |
antidiuretic hormone |
|
hormone diuretic that causes decrease fluid volume (Na+ and H2O) leading to decrease in BP |
Atrial natriuretic peptide (ANP) |
|
Do hormones have a short or longterm effect on regulating BP |
short term - mainly control ventilation not vessels |
|
Longterm effect on regulating BP |
Renal (kidney) control |
|
Direct renal control of BP |
retain or lose fluid to control BP by controlling urine output |
|
Indirect renal control of BP |
hormonal mechanism |
|
Causes alsoterone and ADH release |
Renin-angiotensin-aldosterone system |
|
Kidneys release ____________ ultimately cause the formation of angiotensin II |
renin |
|
Blood flow: _____% to brain _____% to heart _____% to kidneys _____% to digestive _____% to Skeletal muscel |
13 4 20 24 20 |
|
Velocity of blood flow is fastest in _______ slowest in __________ and speeds up in _______ |
aorta capillaries veins |
|
Velocity is inversely related to total ______-______ _______ |
cross-sectional area |
|
when is velocity of blood flow the fastest |
in area of least total area |
|
area of: Aorta Capillaries IVC |
2.5 cm2 2500 cm2 8cm2 |
|
list in order of fastest to slowest blood velocity Aorta Capillaries IVC |
aorta IVC Capillaries |
|
Local regulation of blood flow |
autoregulation |
|
organs control their own arteriols to increase or decrease blood blow via autoregulation using speialized control due to local conditions like ________ _______ and ______. |
CO2 O2 nutrients |
|
blood flow in ________ ________ varies with activity level |
skeletal muscle |
|
at rest ______% of capillaries are open Nor epi keeps _______% closed |
25 75 |
|
Blood flow increases in response to local O2 CO2 and metabolic concentrations causing autoregulation to override sympathetic NS |
Exercise hyperemia |
|
do not tolerate low O2 levels |
neurons in the brain |
|
possesses the most precise autoregulatory system in the body |
brain |
|
the most important stimulus for autoregulation |
carbon dioxide |
|
the ________ has extensive anastomoses for efficient heat control |
skin |
|
__________ stimulation cause vasoconstriction in skin |
sympathetic |
|
in the _______ arteries and arterioles are similar to veins of the rest of the body |
lungs |
|
Pulmonary pressure is __/___ |
25/10 |
|
contracting ventricles compress coronary BV therefore flow stops to the ________ during ventricular ___________. |
heart systole |
|
the heart has a large amount of ___________ to allow for O2 storage |
myoglobin |
|
an _________ in CO2 causes and _________ in vasodilation |
increase increase |
|
blood flow through capillaries |
Capillary dynamics |
|
Gas and nutrient exchange happens by _________. |
diffusion |
|
In capillary dynamics fluid moves in what 2 ways? |
Hydrostatic pressure Osmotic pressure |
|
filtration pressure... pushing pressure. Blood pressure filters fluid from high to low pressure |
Hydrostatic pressure |
|
Based on where particles are due to presence of non diffusible solutes |
Osmotic pressure |
|
water is pulled toward the area with the highest or lowest osmotic pressure? |
highest |
|
Capillary Hydrostatic Pressure |
called filtation pressure... pushing fluid from capillary to interstitial area |
|
what is capillary HP at arteriole end? |
25 mm Hg |
|
How much is Hp at venule end? |
15 mm Hg |
|
how much is interstitial HP? |
-5 (pulling like vacuum) |
|
formula for net hydrostatic pressure |
CHP - IHP |
|
Net hydrostatic pressure at arteriole end |
25- (-5) = 30 mm Hg |
|
Net hydrostatic pressure at venule end |
15 - (-5) = 20 mm Hg |
|
how much is capillary osmotic pressure |
25 mm Hg at both ends |
|
how much is interstitial osmotic pressure |
3 mm Hg both ends of capillary |
|
what is the formula for net osmotic pressure |
capillary osmotic pressure - interstitial osmotic pressure 25 - 3 = 22 |
|
Formula for the direction of fluid movements |
Net HP - Net OP (CHP - IHP) - (COP - IOP) |
|
Direction of fluid moving at arteriol end of capillary |
(25 - (-5)) - (25-3) = 8 mm Hg net Fluid moving out |
|
Direction of fluid moving at venule end of capillary |
(15-(-5)) - (25-3) = -2 mm Hg Fluid moving in |