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20 Cards in this Set
- Front
- Back
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What are the 2 divisions of the autonomic nervous system?
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1. Sympathetic
2. Parasympathetic |
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What is another name(s) for drugs that mimic sympathetic action?
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Adrenergics or Sympathomimetics
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What is another name(s) for drugs that block sympathetic actions?
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Adrenergic Blockers or Sympatholytics
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What is another name(s) for drugs that mimic parasympathetic action?
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Cholinergics or Parasympathomimetics
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What is another name(s) for drugs that block parasympathetic actions?
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Anticholinergics or Parasympatholytics
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What do agonists do?
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Act directly on receptor.
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What do antagonists do?
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Block the receptor.
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What are the receptors for the SNS?
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Alpha1, Alpha2, Beta1, Beta2
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What are the receptors for the PNS?
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Muscarinic and Nicotinic
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What are the primary neurotransmitters of the SNS?
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epinephrine, norepinephrine, and dopamine
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What is the primary neurotransmitter of the PNS?
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acetylcholine; ACh
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What are the primary functions of the SNS?
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Fight or flight response (increased heart rate, dilation of pupils, etc), regulation of the CVS, regulation of body temperature
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What are the primary functions of the PNS?
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Housekeeping chores, slowing of heart rate, digestion, emptying of bladder, bowels, constricting the pupils, etc.
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What are two mechanisms to mimic the action of ACh?
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1. Direct mimicry of ACh
2. Inhibition of the enzyme that breaks down ACh |
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What is the name of the enzyme that breaks down ACh?
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acetylcholinesterase
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Why is ACh rarely used as a drug?
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Because it breaks down too rapidly.
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What are general uses for cholinergics?
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Restore muscle tone in MG patients, Glaucoma patient (pupilary constriction puts less pressure on eye), bladder and GI tract stimulation.
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What is Bethanehol?
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A cholinergic used after surgery to stimulate you to pee since anesthesia can cause urine retention. Also stimulates GI peristalsis.
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When would you not want to use Bethanechol?
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In patients with urinary or bowel obstructions - could cause rupture.
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What are the side effects of Bethanechol?
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Bethanechol is going to activate the parasympathetic nervous system - side effects can include: CV bradycardia, hypotension, diarrhea, excessive salavation, bronchoconstriction
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