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39 Cards in this Set
- Front
- Back
Meiotic Cell Division .. what is produced?
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Sex cells, or gametes
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meiotic includes how many rounds of nuclear division and what are the names?
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meiosis I and meiosis II
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Meiotic cell division results in how many daughter cells?
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four
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How many chromosomes do the daughter cells have in meioitic cell division
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half the number of chromosomes as the parent
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does DNA replication occur before or after prophase I
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occurs before
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prophase I (Meiosis I) : three steps
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1. replicated chromosomes condense -> two sister chromatids
2. synapsis: the homologous chromosomes pair with each other side by side gene for gene (unique to meiosis) 3. chiasmata within bivalents are visible crossovers between non-sister chromatids |
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bivalent
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the result in synapsis.. a four stranded structure
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In Chiasmata, is there a cross over between sister chromatids or non-sister chromatids
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non-sister chromatids
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is there any nucleotrides gained or lost in chiasmata?
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no
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Meiotic Cell DivisionMeiosis I
Metaphase I |
bivalents move to metaphase plate- maternal and paternal homologues randomly distributed
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Meiotic Cell Division Meiosis I
Anaphase I |
homologous chromosomes separate ; centromeres do not split
reductional division |
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Meiotic Cell division Meiosis I
telophase I |
two separate cell produced
genetically different |
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is there any DNA syntehesis between Meiosis I and Meiosis II?
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no
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What is the result of Meiosis II
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four haploid cells, genetically different than parent cell
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Meiosis II
1.Prophase II 2. Metaphase II 3. Anaphase II 4. Telophse II |
1. The nuclear envelope breaks down and the chromosomes condense
2. chromosomes align in center of cell 3. sister chromatids separate 4. the nuclear envelope re-forms |
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what is the product of Meiosis II
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four haploid cells genetically different than parent cell
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Look at comparison in textbook of Mitosis and Meiosis I and Meiosis II
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Table 11.1
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Cytoplasmic Division
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division of the cytoplasm, differs between males and females
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Sexual repproduction involves what two parts?
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meiotic cell division
fertilization |
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meiotic cell division where does it occur
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occurs in ocaries and testes
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meiotic cell division what does it produce
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gametes, sperm and eggs
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how many chromosomes in humans do gametes have
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23 chromosomes
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fertilizaiton what does it do
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unites haploid gametes to produce diploid zygote
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fertilization what does it restore
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restores chromosome number
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Can cell division occur all the time?
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no, this can lead to cancer
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when is dna accurately replicated? which stage?
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s phase
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what if division occurs when cell isnt ready?
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abnormal daughter cells
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cyclical proteins
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bind to and activate cyclin-dependent kinases to control progression through the cell cycle
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enzymes in the cell cycle
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become active and inactive also in cycles, they are called cyclindependent kinases CDKs
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cyclins
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the proteins that appear and disappear cyclically, in cell cycle. activate the cyclinindependent kinases and cell division is promoted
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when are cyclin-dependent kinases active
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always present in the cell however; they are only active with the appropriate cyclin bond.
ex, G1/ S cyclin - CDk complex S cyclin - CDK complex M cyclin CDK complex |
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In order to progress through cell cycle, which checkpoints must be passed first?
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DNA replication checkpoint
DNA damage checkpoint Spindle assembly checkpoint |
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p53.. what and in which checkpoint before the cell cycle would it be viewed in more detail in?
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when dna is damaged by radiation a specific protein kinase is activated that phosphrylates a protein called p53. this occurs in the DNA damage checkpoint
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virus
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protein assemblage surrounding core of RNA or DNA
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oncogene
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cancer-causing gene
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proto-oncogenes
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normal genes important in cell division tha thave the potential to become cancerous if mutated
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tumour suppressors
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encode proteins whose normal activities inhibit cell division
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tumour suppressors act in opposition to ___
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proto-oncogenes
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in order for cell division to occur, what are the two factors that it depends on
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proto-oncogenes -> on
tumour suppressor genes -? off |