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39 Cards in this Set

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Meiotic Cell Division .. what is produced?
Sex cells, or gametes
meiotic includes how many rounds of nuclear division and what are the names?
meiosis I and meiosis II
Meiotic cell division results in how many daughter cells?
four
How many chromosomes do the daughter cells have in meioitic cell division
half the number of chromosomes as the parent
does DNA replication occur before or after prophase I
occurs before
prophase I (Meiosis I) : three steps
1. replicated chromosomes condense -> two sister chromatids
2. synapsis: the homologous chromosomes pair with each other side by side gene for gene (unique to meiosis)
3. chiasmata within bivalents are visible crossovers between non-sister chromatids
bivalent
the result in synapsis.. a four stranded structure
In Chiasmata, is there a cross over between sister chromatids or non-sister chromatids
non-sister chromatids
is there any nucleotrides gained or lost in chiasmata?
no
Meiotic Cell DivisionMeiosis I
Metaphase I
bivalents move to metaphase plate- maternal and paternal homologues randomly distributed
Meiotic Cell Division Meiosis I
Anaphase I
homologous chromosomes separate ; centromeres do not split
reductional division
Meiotic Cell division Meiosis I
telophase I
two separate cell produced
genetically different
is there any DNA syntehesis between Meiosis I and Meiosis II?
no
What is the result of Meiosis II
four haploid cells, genetically different than parent cell
Meiosis II
1.Prophase II
2. Metaphase II
3. Anaphase II
4. Telophse II
1. The nuclear envelope breaks down and the chromosomes condense
2. chromosomes align in center of cell
3. sister chromatids separate
4. the nuclear envelope re-forms
what is the product of Meiosis II
four haploid cells genetically different than parent cell
Look at comparison in textbook of Mitosis and Meiosis I and Meiosis II
Table 11.1
Cytoplasmic Division
division of the cytoplasm, differs between males and females
Sexual repproduction involves what two parts?
meiotic cell division
fertilization
meiotic cell division where does it occur
occurs in ocaries and testes
meiotic cell division what does it produce
gametes, sperm and eggs
how many chromosomes in humans do gametes have
23 chromosomes
fertilizaiton what does it do
unites haploid gametes to produce diploid zygote
fertilization what does it restore
restores chromosome number
Can cell division occur all the time?
no, this can lead to cancer
when is dna accurately replicated? which stage?
s phase
what if division occurs when cell isnt ready?
abnormal daughter cells
cyclical proteins
bind to and activate cyclin-dependent kinases to control progression through the cell cycle
enzymes in the cell cycle
become active and inactive also in cycles, they are called cyclindependent kinases CDKs
cyclins
the proteins that appear and disappear cyclically, in cell cycle. activate the cyclinindependent kinases and cell division is promoted
when are cyclin-dependent kinases active
always present in the cell however; they are only active with the appropriate cyclin bond.
ex, G1/ S cyclin - CDk complex
S cyclin - CDK complex
M cyclin CDK complex
In order to progress through cell cycle, which checkpoints must be passed first?
DNA replication checkpoint
DNA damage checkpoint
Spindle assembly checkpoint
p53.. what and in which checkpoint before the cell cycle would it be viewed in more detail in?
when dna is damaged by radiation a specific protein kinase is activated that phosphrylates a protein called p53. this occurs in the DNA damage checkpoint
virus
protein assemblage surrounding core of RNA or DNA
oncogene
cancer-causing gene
proto-oncogenes
normal genes important in cell division tha thave the potential to become cancerous if mutated
tumour suppressors
encode proteins whose normal activities inhibit cell division
tumour suppressors act in opposition to ___
proto-oncogenes
in order for cell division to occur, what are the two factors that it depends on
proto-oncogenes -> on
tumour suppressor genes -? off