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5 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Alkylating agents |
Nitrogen mustards- Chlorambucil, Cyclophosphamide, Mechlorethamine. Nitrosoureas- Carmustine, Lomustine. Akyl sulfonates- Busulfan Others Cisplatin, Dacarbazine, Procarbazine |
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Rescue therapy |
Alleviate toxic effects of anticancer drugs |
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Methotrexate (Rescue therapy) |
Leucovorin |
a form of tetrahydrofolate that bypasses the dihydrofolate reductase step in folic acid synthesis |
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Cyclophosphamide (Rescue therapy) |
Mercaptoethanesulfonate "mesna" |
traps acrolein released |
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Doxorubicin (Anthracyclines) (Rescue therapy) |
Dexrazoxane |
Inhibits free radical formation and affords protection against cardiac toxicity of anthracyclines |
