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25 Cards in this Set

  • Front
  • Back
Induced fit model
Active Site and Substrate not compementary
Active site is flexible so changes shape
Change in shape allows Enzyme-sub complex to form
Repeating results allows....
Identify anomalies
A more reliable mean to be calculated
Transmittion and course of tuberculosis infection
Mycobacterium tuberculosis trasmited in droplets.
Bacteria engulphed by phagocytes
Bacteria encased in tubercule
Bacteria dormant
When immunosupressed bacteria are active again
Bacteria destroy alveoli
Leads to fibrosis (scar tissue)
This increases diffusion distance
Solutes in the lumen
Lower water potential in the gut
water leaves epithelial cells by osmosis
Control group used for...
Compareing results
See the effect of the drug/whatever else
See if effect due to something else in tablet
Good things about vaccinations
Prevents the disease occuring
Cheaper to accinate than treat disease
Disease destroyed in those vaccinated,
so stops spread of the disease
Problems with vacccinations
Vacccinations are costly

Don't know is research done in mice will repliacate in humans

Individuals may develop disease being vaccintaed against straight away if immune system to weak

May make people test posotive for that disease

Pathogen may mutate frequantly, so antigens change suddenly and vaccination no longer effective
risk factor
Something that increases the chance of something happening
Structures of a prokaryotic cell (bacteria)
Capsule (slime layer)
plasmid
Flagellum
70s ribosomes
call wall made of peptidoglyclan
Pillus
Mitochondria
Site of aerobic respiration to produce ATP and so provide energy
Enzyme question comes up
Active site specific shape
Shape complenatery to sub, so bind to sub
This forms enzyme sub complexes
Why use healthy people in investigation

Why use people of same age
They tend to have normally fuctioning body parts

Age affects ________ (thing being tested)
Question about enzymes
Think Active sites
xm=1000xmm=1,000,000xum
0.1m=100mm=100,000um
Monoclonal antibodies
Antibodies produced from a single clone of B cells/ single B cell
Is a graph levels out. it can be said to have
Plateaued or is constant
If asked to evaluate claim
Give 1 reason for, 1 against then find issues with the experiment i.e Only one investigation/test/need more studies;
If a graph fall then levels out, say...
graph decreases between x and y and then no further dercease due to no further ______ (factor from Question).
Consider when giving drug
Dose to be given
Any (serious) side effects
How effective
Cost of drug
TEM
Focused beam of Electrons
Higher reolution
2-D image
Sample must be v. thin
Artefacts due to staining process
SEM
Scans with electrons
Lower resolution
Can be done on thicker sample
3-D image
Artefacts due to staining
Sucrose

Maltose

Lactose
Alpha glucose and fructose

2x alpha glucose

alpha glucose and galactose
Dont mix up describe and EXPLAIN
!!!!!!!!!!!!!!!!!!!!!!!
If question gives you text about something (penultamate Q) and asks a question about something on a particular line....
Refer to it in context of question
Atheromas
fatty materials and LDL, in wall of artery (under endothelium of artery)

Blocks coronary artery, Less oxygen/glucose to heart muscle/cells/tissue so Reduces/prevents respiration so casues myocardical infarction