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126 Cards in this Set
- Front
- Back
Definition of Biochemistry:
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The study of chemical processes within and relating to living organisms
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Definition of an atom:
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The smallest component of an element that still has original properties - consisting of a positively charged nucleus surrounded by a charged cloud of electrons.
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Proton:
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Particle in the nucleus with a positive charge of +1 and an atomic mass number of 1 dalton
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Neutron:
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non-charged nuclear particle with the same mass as the proton
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Electron:
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Negatively charged particle with a mass 1/1837 of that of a proton
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Element:
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A substance that
a) cannot be broken down into simpler substances by chemical means b) is composed of atoms all of which have the same number of protons in nucleus. There are 92 natural occurring elements that have been discovered |
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What is the most common element in the universe? What is the second most common element in the universe?
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1) Hydrogen
Followed by: 2) Helium |
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What element provides the basic structure of all organic compounds?
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Carbon
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What element is represented by the chemical symbol "C"?
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Carbon
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Atomic Number and Electron outer shell of Carbon?
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Atomic number: 6
Electron Outer Shell: 4 |
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Atomic Number and Electron outer shell of Oxygen?
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Atomic number: 8
Electron outer shell: 6 |
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What element is part of most classes of biological molecules; and required in aerobic metabolism?
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Oxygen
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What element has the Chemical symbol "O"?
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Oxygen
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What is the Atomic Number and Number of Outer Shell Electrons for Hydrogen?
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Atomic Number: 1
Number of Outer Shell Electrons: 1 |
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What element is represented by the chemical symbol "H"?
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Hydrogen
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What element is abundant in biological molecules? This element's ionic form (H+) is also important in many ways...
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Hydrogen
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What element is represented by the letter "N"?
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Nitrogen
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What is the atomic number for nitrogen? What is the number of outer shell electrons?
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Atomic number: 7
Outer Shell electrons: 5 |
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What element is important in the structure of proteins, nucleic acids, and many other types of molecules?
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Nitrogen
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What Element has the chemical symbol "S"?
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Sulfur
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What is the atomic number and number of outer shell of electrons in Sulfur?
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Atomic number: 16 Outer shell electrons: 6 |
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What element is an important part of cysteine, an amino acid in many proteins?
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Sulfur
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What element is represented by the chemical symbol "P"?
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Phosphorus
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What is the atomic number and number of outer shell electrons for Phosphorus?
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Atomic number: 15
Outer Shell Electrons: 5 |
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What element is a component of nucleic acids; important part of cell membrane molecules called phospholipids; part of ATP the universal energy molecule?
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Phosphorus
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What is the chemical symbol for Iron?
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Fe
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What is the atomic number and number of outer shell electrons for Iron?
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Atomic number: 26
Outer shell electrons: 2 |
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What element is a central component of hemoglobin?
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Iron
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What is chemical energy?
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The potential of a chemical substance to undergo a transformation through a chemical reaction or, to transform other chemical substances
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Chemical reactions:
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usually involve the making or breaking of chemical bonds. Oxidation, reduction, dissociation, synthesis, acid-base neutralization and molecular rearrangement are some of the commonly used kinds of chemical reactions
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A molecule is two or more atoms linked by a ____________________.
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chemical bond
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If atoms are sharing electrons, then the bond between them is __________________.
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covalent.
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If an atom gives up an electron to another atom, then they have an______________.
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Ionic bond.
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Hydrogen bonds result from:
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electrostatic attraction between an electronegative atom (O or N) and a hydrogen atom that is bonded covalently to a second electronegative atom (strong surface tension of H20).
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Definition of a compound:
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A substance with a particular ratio of atoms of particular chemical elements which determines its composition, and a particular organization which determines chemical properties. These include: Carbohydrates, lipids, proteins, and vitamins.
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Definition of ion:
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A charged species, an atom or molecule, that has lost or gained one or more electrons.
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Definition of a cation:
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Positively charged ion
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Definition of an anion:
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Negatively charged ion
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Solution:
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A homogeneous mixture composed of only one phase.
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Solute/Solvent
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A solute is a substance dissolved in another substance known as a solvent.
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A substance that produces hydronium ions (H+) when dissolved in water is an
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Acid
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A substance that produces hydroxide ions (OH-) when dissolved in water (H20).
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Base
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A PH of 7.0 is
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Neutral
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A solution with a lower pH (1-6) is
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Acidic
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A solution with a higher pH (8-14) is
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Basic
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Characteristics of Acids
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Release H+
Taste sour React strongly with metals (Zn + HCl) Are dangerous and can burn your kin Turn red litmus paper blue |
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Characteristics of Bases
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Accept H+
Taste bitter Denature protein - feel slippery Can be very dangerous and can burn your skin Turn blue litmus paper red |
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What are the four main classes of (bio) macromolecules?
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Carbohydrates
Lipids Proteins Nucleic Acids |
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Carbohydrates are made from what kind of monomers?
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Monosaccharides
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Glucose (C6H12O6), fructose (C6H12O6), and deoxyribose (C5H10O4) are what classification of sugars?
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Monomers/monosaccharides
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Sucrose, Lactose, and Maltose are
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Disaccharides
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What is sucrose made up of?
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glucose + fructose
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What is lactose made up of?
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Glucose and galactose
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What is maltose made from?
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Glucose + glucose
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What breaks down sucrose, lactose, and maltose respectively?
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sucrase, lactase, and maltase
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_____________ is made by plants and is an important structural component of their cell walls.
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Cellulose
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Cellulose and chitin are examples of ______________ _______________ composed of glucose molecules
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structural polysaccharides
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_______________ is an animal carbohydrate; humans ad other animals use it as a form of energy storage.
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Glycogen
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Glycogen is the analogue of _________, a glucose polymer and energy storage in plants, having a similar structure to amylopectin (a component of starch - broken down by amylase).
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starch
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The liver can regenerate glucose from glycogen using a process called ________________.
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gluconeogenesis
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______________ are usually made from one molecule of glycerol combined with other molecules.
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lipids
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What is the main group of bulk lipids?
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triglycerides
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What are triglycerides made of?
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One molecule of glycerol and three fatty acids
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In the case of triglycerides, fatty acids are considered what?
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monomers
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When fatty acids are found in triglycerides the may be in two forms. What are these forms?
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saturated (no double bonds)
unsaturated (one or more double bonds) |
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What two fatty acids are considered essential?
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Linolenic and linoleic
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_______ comprise a diverse range of molecules and to some extent is a catchall for relatively water-insoluble or non polar compounds of biological origin
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Lipids
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Waxes, fatty acids, fatty-acid derived phospholipids, sphingolipids, glycolipids, sterols, fat-soluble vitamins (A,D,E,K) and terpenoids (retinoids and steroids) all belong to what category?
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Lipids
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What is the name for lipids solid at room temperature?
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Fats
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What is the name for lipids which are liquid at room temperature?
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Oils
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How are lipids broken down in the digestive system?
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By lipase (aided by bile)
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In animals, when there is an oversupply of dietary carbohydrate, the excess carbohydrate is converted to what?
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Triglycerides
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How are excess carbohydrates converted to triglycerides? What is this process called?
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Involves the synthesis of fatty acids from acetyl-CoA and the esterification of fatty acids in the production of triglycerides. This process is called lipogenesis.
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What hormone stimulates lipogenesis?
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Insulin
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What do Lipoproteins, synthesized by the liver, accomplish?
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Transport endogenous triglycerides and cholesterol.
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Lipoproteins circulate through the blood continuously until the TGs they contain are taken up by peripheral tissues or the lipoproteins themselves are cleared by the liver. What are examples of these lipoproteins?
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Very-low-density lipoproteins (VLDL)
Low-density lipoproteins (LDL) High-density lipoproteins (HDL) |
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___________ are very large molecules - macro-biopolymers - made from monomers called amino acids?
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Proteins
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There are _____ standard amino acids in the human body. ____ amino acids are considered essential in the adult human.
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20
8 |
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When amino acids combine, they form a special bond called a peptide bond through dehydration synthesis, and become a ________________, or protein.
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polypeptide
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Ingested proteins are usually broken up into single amino acids or dipeptides in the small intestine by these enzymes in the small intestine....and then absorbed.
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proteases
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What is the "nitrogen or amino acid pool"?
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A grand mixture of amino acids available in the cell derived from dietary sources or the degradation of protein.
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When is a nitrogen balance achieved by a healthy person?
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When the dietary intake is balanced by the excretion of urea wastes.
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Nucleic acids are biological molecules essential for life and include (2 names)
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DNA and RNA
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Alcohol is metabolized by several processes or pathways. The most common of these pathways involves what two enzymes?
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alcohol dehydrogenase (ADH)
aldehydedehydrogenase (ALDH) |
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Ethanol, Methanol, Isopropyl, Glycerol, Menthol, Xylitol, Mannitol, and Sorbitol are all types of what?
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Alcohols
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___________ is the metabolic reaction cells undergo to extract energy
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Catabolism
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____________ is the metabolic reaction cells undergo to construct new compounds and requires energy
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Anabolism
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What is the Glycemic Index (GI)?
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A ranking of carbohydrates on a scale from 0 to 100 according to the extent to which they raise blood sugar levels after eating.
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Foods with a high GI are those which
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are rapidly digested and absorbed and result in marked fluctuations in blood sugar levels
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Low-GI foods are those which
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by virtue of their slow digestion and absorption, produce gradual rises in blood sugar and insulin levels.
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____________ are molecules that accelerate, or catalyze, chemical reactions
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Enzymes
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During enzymatic reactions the molecules at the beginning of the process are called___________ and the enzyme converts these into different molecules called _________.
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substrates, products
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Most enzymes are_________
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proteins
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Enzymes may be aided by ____________ or ____________.
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cofactors, coenzymes.
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___________ and __________ can serve as precursors to many organic cofactors
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Vitamins and minerals
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Define isotope
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Atoms with the same number of protons and electrons, but different numbers of neutrons
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Define molecules
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Distinctive structures composed of atoms that are chemically bonded to each other. Each kind of compound is composed of molecules that have a particular number and arrangement of atoms
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Chemical formula: H2 O
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Water
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Chemical formula: C O2
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Carbon Dioxide
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Chemical formula: N H3
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Ammonia
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Chemical formula: C6 H12 O6
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Glucose (Sugar)
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Chemical formula: C3 H7 OH
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Rubbing alcohol
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Describe the arrangement of the periodic table of elements:
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Elements are arranged in a series of rows (or periods) so that those with similar properties appear in vertical columns. Elements of the same period have the same number of electron shells; with each group across a period, the elements have one more proton and electron and become less metallic. Elements are represented by a chemical symbol, with atomic number and mass number.
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Define energy:
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An attribute of a substance as a consequence of its atomic, molecular or aggregate structure.
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When is a reaction said to be exothermic?
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If the reaction releases heat to the surroundings
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When is a reaction said to be endothermic?
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the reaction absorbs heat *from* the surroundings
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Chemical symbol: Na
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Sodium
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What is the atomic number and number of outer shell electron for Sodium?
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Atomic number: 11
Outer shell electron: 1 |
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What is the function of sodium?
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Important in sodium/potassium pumps in cell membranes of nerve cells and muscle cells; important in many physiological aspects such as maintenance of osmotic balances
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Chemical symbol: Ca
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Calcium
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Atomic number/Outer shell electron number
for Calcium |
Atomic number: 20
Outer shell electrons: 2 |
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What is the function of calcium
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Abundant in bones; important in nerve function and muscle function
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Chemical symbol: K
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Potassium
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Atomic number/Outer electron shell:
Potassium |
Atomic number: 19
Outer electron shell: 1 |
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Chemical symbol: Cl
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Chlorine
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Atomic number/Outer shell electron :Cl
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Atomic: 17
Outer shell electron: 7 |
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Function of Chlorine
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Important ion in many solutions of living things
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Chemical symbol: I
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Iodine
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Atomic numer/ Outer shell electrons: Iodine
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Atomic: 53
Electrons: 7 |
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Function of Iodine
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Trace element, but critical component of vertebrate thyroid hormone
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Chemical symbol: F
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Fluorine
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Atomic number/Outer shell electrons: Fluorine
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Atomic number: 9
Outer shell electrons: 7 |
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Function of Fluorine
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Trace component in bones and teeth
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Chemical symbol: Zn
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Zinc
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Atomic number/Outer shell electrons: Zinc
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Atomic number: 30
Outer shell electrons: 2 |
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Function of Zinc
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Trace element; part of some enzymes
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