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63 Cards in this Set
- Front
- Back
3 functions of the lymphatic system
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drain excess fluid (leakage from circulatory system, fluids from cells)
transport of lipids from small intesting moves non-self material |
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Spleen, filters
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removes pathogens, old cells dibris
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2 compartments of spleen
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red pulp (RBC)
white pulp (WBC) |
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thymus
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differnt lymphocytes
secreted hormones |
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two lines of deffense
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innate defense (non specific)
defense due to structure do NOT require pathogens Aquired defense mechanisms (specific) defense due to cellular response require pathogen |
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innate defense mechanisms include
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surface barriers
skin secretion of chemicial compounds mucasal linings |
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microflora
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bacteria on body
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secretion of chemical compounds
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adjust PH of body
salts - hypotonic lysosomes |
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leukocytes WBC types
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macrophage
natural killer cells complement proteins |
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macrophage
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eat non-self material
phagocytosis |
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natural killer cells
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target cancerous cells
target infected cells targeted cells undergo program cell death |
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complement proteins
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common component of blood plasma
part of the complement system |
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membrane attack complex
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blah this is confusing
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inflamatory response
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reaction to trauma
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steps to inflammation response
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physical penetration of skin
early events edema late events |
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early events of inflammation response
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release of chemicals by not motile connictive tissue
vascular constriction vascular dialation increased blood flow (warmth and redness) |
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edema
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fluid accumulation @ site (swelling)
dilution of toxins influx od lekocytes influx of complement proteins pus may form |
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late events
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immune cells go to injury
macrophages come cells produce antibodies fever may be induced (bacteria cannot live above certain temp) |
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immune response triggered by
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allergen
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most of bodies immunbe responses use
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lymphocytes
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B-Cells
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Differentiated in BONE marrow
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plasma cells produce
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antibodies
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memory cells
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don't make antibodies
allows for quick response |
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bcells provide
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antibody mediated immunity
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T cells
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differiented in thymus
no antibodies |
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t cells can
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target non self cells and kill them
put off chemical signals cell mediated community cell |
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how does the body recognise itself
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cells that code for self
major histocompatibility complex genes of complex proteins |
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B cells
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produce antibodies (via plasma cells)
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b cell antibodies composed of
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4 proteins forming a y shape
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tip of y (b cell antibody)
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binds antibodies to cell and stimulate phagocytosis
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colonal selection theory
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a specific antigen stimulates only a few b cells to repoduce
produces b cell lineage each cell has idential genes forms a population of b cells that can become plasma cells forms antibodies against antiggen that stimulates repro |
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due to mutations many b cells are made to recognise and respond to
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antigen before antigen introduced
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you can be born with b cells
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that can help you out
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plasma cells (are b cells)
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antibody producing factory (2000 antibodies a second)
cells las 5-7 days |
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memory cells
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provide rapid response
last a long time |
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types of t cells
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t helper cells
t suppressor cells t delayed type hypersensity cells t cytotxic cells |
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t helper cells
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help immune system function
produce chemicals that regulate systems |
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t suppressor cells
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release chemicals that stop an immunse response
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t dth cells
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release chemical activates macrophage and stops their migriting
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t cytotxic cells
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kills non self cells
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all organisms must
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maintain osmotic balance
take in resources expel wastes transpot molecules |
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how transport and mainting balance is done in simple animals
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diffusion
osmosis facilitated diffusion |
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more complex animals
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are larger
can no longer rely on positive transport more resources and more wastes |
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circulation evolved to
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maintain homeostasis
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open circulatory system
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body cavity is open to circulatory fluid
fluids move by simple pump not efficent |
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closes circulatory system
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fluids sent to different areas of body cavity
(series of tubes, effient, unidirectional) |
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when system is increased in complexity
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flow of blood need to be redirected to lungs
pulmonary system systematic system |
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plasma
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60% of blood
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plasma contains
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proteins
nutrients clotting factors defense reactions |
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rbc
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eruthrocytes
transport and transfer |
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wbc
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leukocytes
deals with bodies autoimmune many different |
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platlets
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clotting
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2 paths of cv system
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pulmonary circut
systemic flow |
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pulmonary circut
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to lungs and arteries
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systemic flow
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rest of body
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how blood flows
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right atrium > tricuspid > right ventricle > semilunar valve > pulmanary circut > lungs > aleoli exchange gasses > pulmanry vein > left atrium > bicuspid > left ventricle > semilunar circut > systematic circut >leaves through aorta > venuals > veins > vana cava > right atrium
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when heart is relaxed
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blood enters
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distole
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heart is relaxed
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systole
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heart is constricted
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when heart contracts
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first atria contracts, thing ventricals contract
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SA NODE
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is pacemaker (contracts heart)
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AV node
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delay point
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What happens when signal reaches AV node
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delays signal, atria fully contracted
vntricles conract then the signal is passed to the apex of heart |