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23 Cards in this Set

  • Front
  • Back
DNA
Nucleic acid that contains genetic instruction.

DNA consists of two long polymers of simple units called nucleotides, with backbones made of sugars and phosphate groups joined by ester bonds.

Exhibits quaternary structure in Chromatin
RNA
RNA is made up of nucleotides. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate group

Exhibits quaternary structure in interaction of RNA units in ribosomes
Components of nucleotides
1. a 5 carbon sugar
2. a phosphate
3. a nitrogenous base
Purines
2 ring bases

Adenine and Guanine
Pyrimidines
1 ring bases

Thymine / Uracil
Cytosine
DNA and RNA complementary base pairs
DNA:
A-T (2 hydrogen bonds)
G-C (3 hydrogen bonds)

RNA:
A-U
G-C
Nucleotide chain:
Bond and Reaction?
Phosphodiester bonds via condensation reaction
DNA molecules differ in?

3 ways
# of base pairs
relative quantity of base pairs
sequence of base pairs
Circular DNA
form of DNA that is found in viruses, bacteria and archaea as well as in eukaryotic cells in the form of either mitochondrial DNA or plastid DNA.
Linear DNA
DNA structure that has free ends
3 structure forms of DNA
1. Single and double stranded
2. linear and circular
3. 3 Dimensional (B,A,Z DNA)
Z-DNA
This helix is left-handed and has a structure that repeats every 2 base pairs
B-DNA
This is the most common DNA.

Right-handed helix. Structure repeats every 1 base pair.
A-DNA
Right-handed helix. More base pairs per turn than B-DNA.

Repeats every 1 base pair.
RNA vs DNA hydrolysis?
Chemical and Enzymatic hydrolysis

Chemical:
DNA is stable to bases (alkaline hydrolysis). This is one of the features which distinguish DNA from RNA (RNA is not stable under alkaline conditions).

Enzymatic Hydrolysis
RNA vs DNA structure?
RNA is:
Smaller in length than DNA
Single-stranded
Shape Variable

Shape variable:
Straight/Folded
When folded, shape maintained by base pairing
No double helix
RNA types (5):
mRNA (messenger)
rRNA (ribosomal)
tRNA (transfer)
snRNA (small nuclear)
hnRNA (heterogenous nuclear)
Function of RNA?
protein synthesis
mRNA
encodes and "carries" information from DNA during transcription to whatever sites are undergoing protein synthesis


A type of RNA, synthesized using a DNA template, that attaches to ribosomes in the cytoplasm and specifies the primary structure of a protein.
rRNA
basically makes the proteins


RNA molecules that, together with proteins, make up ribosomes; the most abundant type of RNA.
tRNA
transfers correct amino acids to a growing polypeptide chain


An RNA molecule that functions as a translator between nucleic acid and protein languages by carrying specific amino acids to the ribosome, where they recognize the appropriate codons in the mRNA.
hnRNA
Precursor of mRNA
snRNA
guide chemical modifications of rRNA's

Found in eukaryotic nuclei