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23 Cards in this Set
- Front
- Back
DNA
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Nucleic acid that contains genetic instruction.
DNA consists of two long polymers of simple units called nucleotides, with backbones made of sugars and phosphate groups joined by ester bonds. Exhibits quaternary structure in Chromatin |
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RNA
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RNA is made up of nucleotides. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate group
Exhibits quaternary structure in interaction of RNA units in ribosomes |
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Components of nucleotides
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1. a 5 carbon sugar
2. a phosphate 3. a nitrogenous base |
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Purines
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2 ring bases
Adenine and Guanine |
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Pyrimidines
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1 ring bases
Thymine / Uracil Cytosine |
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DNA and RNA complementary base pairs
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DNA:
A-T (2 hydrogen bonds) G-C (3 hydrogen bonds) RNA: A-U G-C |
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Nucleotide chain:
Bond and Reaction? |
Phosphodiester bonds via condensation reaction
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DNA molecules differ in?
3 ways |
# of base pairs
relative quantity of base pairs sequence of base pairs |
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Circular DNA
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form of DNA that is found in viruses, bacteria and archaea as well as in eukaryotic cells in the form of either mitochondrial DNA or plastid DNA.
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Linear DNA
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DNA structure that has free ends
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3 structure forms of DNA
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1. Single and double stranded
2. linear and circular 3. 3 Dimensional (B,A,Z DNA) |
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Z-DNA
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This helix is left-handed and has a structure that repeats every 2 base pairs
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B-DNA
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This is the most common DNA.
Right-handed helix. Structure repeats every 1 base pair. |
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A-DNA
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Right-handed helix. More base pairs per turn than B-DNA.
Repeats every 1 base pair. |
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RNA vs DNA hydrolysis?
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Chemical and Enzymatic hydrolysis
Chemical: DNA is stable to bases (alkaline hydrolysis). This is one of the features which distinguish DNA from RNA (RNA is not stable under alkaline conditions). Enzymatic Hydrolysis |
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RNA vs DNA structure?
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RNA is:
Smaller in length than DNA Single-stranded Shape Variable Shape variable: Straight/Folded When folded, shape maintained by base pairing No double helix |
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RNA types (5):
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mRNA (messenger)
rRNA (ribosomal) tRNA (transfer) snRNA (small nuclear) hnRNA (heterogenous nuclear) |
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Function of RNA?
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protein synthesis
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mRNA
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encodes and "carries" information from DNA during transcription to whatever sites are undergoing protein synthesis
A type of RNA, synthesized using a DNA template, that attaches to ribosomes in the cytoplasm and specifies the primary structure of a protein. |
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rRNA
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basically makes the proteins
RNA molecules that, together with proteins, make up ribosomes; the most abundant type of RNA. |
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tRNA
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transfers correct amino acids to a growing polypeptide chain
An RNA molecule that functions as a translator between nucleic acid and protein languages by carrying specific amino acids to the ribosome, where they recognize the appropriate codons in the mRNA. |
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hnRNA
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Precursor of mRNA
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snRNA
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guide chemical modifications of rRNA's
Found in eukaryotic nuclei |