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41 Cards in this Set

  • Front
  • Back
what is the point of DNA
it's a code that gives us the order for a sequence of amino acids
what is the reaction that combines amino acids
condensation
what do amino acids joined together form
A polypeptide chain
where is DNA found
the nucleus
where are proteins synthesized
cytoplasm
what is 'central dogma'
the production of mRNA which is read by ribosomes to position tRNA into a particular sequence forming a particular protein.
what is the role of mRNA
A messenger molecule, it transfers the DNA code from the nucleus to the cytoplasm because it is small enough to leave through the nuclear pores.
what are the structural differences between DNA and RNA
RNA remains single stranded
RNA contains uracil
RNA has ribose sugar back bone
DNA contains thymine
DNA has deoxyribose back bone
when is mRNA produced
the first step of protein synthesis
where is mRNA produced
in the nucleus when DNA is unraveled exposing a template stand for free RNA nucleotides to assemble
what enzyme is responsible for the unraveling of DNA
DNA helicase
How many nucleotides are exposed at any one moment
No more than 20
is mRNA identical or complementary to the DNA template from which it has been formed
complementary
after pre-mRNA is formed what happens
pre-mRNA leaves the nucleus through a nuclear pore where it attaches to ribosome which acts as a scaffold to form proteins on.
what do the bases of mRNA indicate
the order of amino acids in the polypeptide chain (protein) that is being made
what is a codon
3 nucleotide bases that code for an amino acid
what is a degenerate code?
when an amino acid has more than one cousin
what mark the end of a polypeptide chain
A stop codon, for which there are three.
the triplet code prevents
overlapping of amino acids
the triplet code is universal, what does this mean
the same codon codes for the same amino acid in all organisms.
structural features of tRNA
single stranded and folded into a cover leaf shape, contains uracil, very small
what is the role of tRNA
to bring amino acids to a ribosome during protein synthesis.
the process of producing a protein from DNA
what is transcription
the production of mRNA by using DNA as a template
what is translation
translating the base sequence of mRNA into an amino acid sequence.
what is the function of RNA polymerase
to form phosphodiester bonds (sugar phosphate backbone) to produce a single stand of pre-mRNA complementary to the DNA base sequence
when does RNA polymerase detach from the DNA and pre mRNA
when it reaches a stop codon, pre-mRNA is complete
what bonds does DNA helicase break
hydrogen bonds between bases
what happens when ends polymerase detaches?
the DNA rewinds forming hydrogen bonds between it's bases
does all DNA code for proteins?
No, only 2% is coding DNA the other 98% is non-coding
exons are...
coding sections of DNA and pre-mRNA
introns are...
non coding sections of DNA and RNA
what happens to separate introns and exons
useful exons are removed from pre-mRNA and spliced together to form a final strand of mRNA.
what is translation
the synthesis if the polypeptide
tRNA contains a complementary _ _ _ _ _ _ _ _ _ to the mRNA
anticodon
what is attached to the tRNA
the amino acid that is specific to the anticodon.
what is the job of the ribosome in translation
to bring complementary tRNA molecules to the mRNA, it brings two tRNA molecules at a time.
what bond is formed between amino acids in a condensation reaction
A peptide bond
what is used to join amino acids?
an enzyme and ATP
once the amino acids are bonded what happens to the tRNA
it is released so it can collect another amino acid.
what is the process called when many ribosomes travel laying the mRNA at the same time
polysome