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65 Cards in this Set

  • Front
  • Back

4 requirements for a micro-organism to be considered a pathogen

Gain entry to a host


Colonise the host tissue


Resist the hosts defences


Cause damage to host tissues





What is infection

The colonization of host tissues

What is disease

Where an infection leads to recognisable symptoms

What is the name of passing one pathogen from person to person

Transmission

What is a correlation

Something that occurs when a change in one or two of the variables is reflected by a change is the other variable

What is risk

A measure of the probability that damage to health will occur as a result of a given hazard

What specificity doe health risks require

A time-scale i.e not "you will die" but "you will die next month"

Risk is often...

Relative

What two factors increase the risk of cancer

Environmental and Carcinogenic

Name 5 lifestyle factors that could lead to the development of cancer

Smoking


Sunlight


Diet


Obesity


Exercise



What are lifestyle factors

Factors we can control

Three ways that exercise reduced the risk of CHD

Reduces blood pressure


Reduced cholesterol


Reduced risk of obesity

How does aerobic exercise benefit health

Lowers blood pressure and cholesterol

Where are enzymes produced in the stomach and small intestine

Glands in the stomach/ intestine wall

Where does the water that is re-absorbed in the large intestine come from

Secretions of digestive glands

Name three components of pancreatic juices

Proteases, Lipase and Amylase

What is hydrolisis

The splitting up of molecules by adding water to the chemical bonds that hold them together

What is assimilation

Incorporating absorbed molecules into body tissue

What is the generic term for digestive enzymes

Hydrolayses

Why are many molecules carbon based

Carbon readily forms bonds with other atoms

Name two biological molecule polymers

Carbohydrates and Proteins

What four elements are most polymers based on

Oxygen


Carbon


Nitrogen


Hydrogen



What is another name for sugar

Saccheride

What is the general formula of sugars

(CH2O)n

What is reduction

A chemical reaction involving the gain of electrons

On an atomic level what occurs to reducing sugars during reduction

Whey donate electrons to another chemical i.e benedicts reagent

Describe the process of testing for reducing sugars

Add an alkaline solution of copper sulphate to the test sample then heat

What is produced to show the presence of reducing sugars

A red precipitate of copper oxide

Why is the benedicts test semi-quantative

It has different colours depending on the concentration of sugar present so can be used to estimate the concentration

How do the colours range in a benedicts test

From clear -green-yellow-brown-red

How could concentrations of sugar be estimated

Dry the precipitate in the sample and weigh it

Describe the benedicts test for non-reducing sugars

Ground up with water (solid samples) then add dilute hydrochloric acid and place in a gently boiling water bath

How is a sample of non-reducing sugar neutralized

Addition of sodium hydrogen carbonate

How does amylase react with starch

It hydrolyses alternate bonds to form maltose

Apart from amylase what does saliva contain

mineral salts that act as a buffer to keep the PH at neutral

How do the pancreas and intestinal wall control the PH for enzymes

Secretions of alkaline mineral salts

Why has the problem of lactose intolerance increased

Transport and storage means the population consumes more milk than in earlier years

What two products form when micro-organisms break down undigested lactose

Small soluble molecules and gasses

Why may diarrhoea occur from lactose intolerance

Micro organisms produce soluble molecules that lower the water potential of the lumen

What do two amino acids form through a condensation reaction

A dipeptide

How is water produced from the condensation of amino acids

OH from the carboxyl group


H from the amino group

What is the name of the process of forming polypeptides trough condensation reactions

Polymerisation

Which structure of a protein determines its properties

Its primary structure as it determines the shape of a polypeptide

Give an example of a fibrous protein

Collagen

Why are mammalian lungs located inside the body

Air is not dense enough to support the lungs


They would otherwise dry up and lose water

Describe the structure of the tracheal walls

Muscle lined with ciliated epithelium and gob;let cells that produce mucus

How is air flow in the alveoli regulated

By the muscle on the walls of the bronchioles

Describe the intercostal muscle movements during inspiration and expiration

Internal intercostal contracts during expiration


External intercostal contracts during inspiration

Breathing is a largely.................process

Passive

How is most air forced out of the lungs

Elastic recoil of the lung tissue

When do muscles play a part in expiration

During strenuous conditions such as excersise

What is pulmonary ventilation

The total air volume moved in the lungs in one minute

What is tidal volume

Volume of air taken in each breath

How is pulmonary ventilation calculated

PV = Tidal volume x ventilation rate

What are the 5 features of an exchange surface

Large SA:V ratio


External medium moves


Internal Medium moves


Short diffusion pathway


Partially permeable

What is diffusion proportional to

Surface area x concentration difference/length of diffusion pathway

Why are exchange surfaces easily damages

They are thin

Why is diffusion of gas in the lungs fast

Red blood cells are slowed


RBC pressed against the wall


Capillary walls are thin


Large SA

What are 3 symptoms of TB

Cough


Tiredness


Loss of appeite

What increases the risk of TB

Those who live in close contact


Work in long term care facilities


TB common countries


Reduced immunity

Describe the primary TB infection



Bacteria colonise the upper regions of the lungs and white blood cells accumulate at the area. This leads to inflammation of the lymph nodes.

Describe the post-primary TB infection

The bacteria destroy the lung tissue and this results in cavities and scar tissue where the lungs repair themselves

What are the four symptoms of pulmonary fibrosis

Shortness of breath


Chronic dry cough


Pain in the chest


Weakness

How does pulmonary fibrosis damage the lungs


3 ways

Thickens the alveoli epithelium which increases the diffusion pathway and decreases the volume of air capacity in the lungs. Reduces elasticity

How does emphysema affect the lung tissue

The elastin becomes permanently stretched and so the lungs can not force out all the air. The SA is reduced as the alveoli sometimes burst. Flow rate decreases. This inhibits gas exchange