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155 Cards in this Set

  • Front
  • Back
How many functional olfactory genes do humans have?
About 400
This is the destination point in which sensory cells of the same type synapse.
Glomerulus
Receives signals from the glomerulus, which then carries the signal to the olfactory bulb
Mitral cell
This is the destination of olfactory signals after reaching the olfactory bulb.
The limbic system and cerebral cortex;
Olfactory receptor cell -> Olfactory nerve fiber -> Olfactory bulb -> Olfactory Tract -> Limbic System OR (Thalamus -> Cortex)
How many basic smells do human beings have?
Ten
What are the ten basic smells?
Sweet, fragrant, woody, fruity, chemical, minty, popcorn, lemon, decaying, pungent
About how many smells can humans detect?
1 trillion
This organ conducts chemoreception of pheromones
Vomeronasal organ; humans do NOT have vomeronasal nerves
What does the mammalian vomeronasal organ do?
Detect pheromones and chemical signals
True or False: A single olfactory neuron expresses many different olfactory receptive genes.
False
TRP stands for
Transient Receptor Potential Channel
This chemical triggers cold TRPs
Menthol
This chemical triggers warm transient receptor potential channels
Capsaicin
This the ability of animals to use magnetic fields to navigate.
Magnetoreception
These small crystals in some animals float in a liquid and rotate in sync with magnetic fields.
Magnetite crystals
This molecule is found in the eyes of birds, helping it to navigate.
CPF
Photosensitive cells use this to absorb light.
Rhodopsin
Steps in eye evolution hypothesis:
1. Photosensitive cells use rhodopsin to absorb light
2. PAX6 gene initiates eye development
3. Proto-eyes use pigment cells to make photoreceptors sensitive to light from one direction
4. The eye develops into a simple or compound eye
okay
What is the difference between simple and compound eyes?
Compound eyes made up of several sets of light and color detecting parts, positioned on the top or sides of the organism. Simple eyes have a limited range of sight and can only see certain lights and colors.
How many types of photoreceptors do humans have?
3
These cells are the output of the retina
Ganglion
This is the area of the retina within which the membrane potential of a particular neuron can be influenced by light.
Receptive field
Rhodopsin is made of:
Retinal and Opsin
In the dark, rhodopsin is:
Inactivated
True or false: Phototransduction closes Na+ channels
True
Photoreceptor channels are open in the dark, allowing ions to flow in and out. Cyclic GMP keeps the channels open. A single photon of light can activate rhodopsin. Rhodopsin activates transducin molecules. Each transducin (G Protein) activates about 70 photodiesterase. Phosphodiesterase can hydrolyze cyclic GMP, closing ion channels allowing ions to flow inward, but outward (Na+) channels remain open. The cell becomes hyperpolarized.
Okay
What keeps photoreceptor channels open?
Cyclic GMP
True or False: Light depolarizes photoreceptors
False, light HYPERPOLARIZES photoreceptors
When photoreceptor cells are DEPOLARIZED and rhodopsin is INACTIVE, what is happening with regards to neurotransmitters?
Neurotransmitters are being released onto bipolar neurons
When photoreceptor cells are HYPERPOLARIZED and rhodopsin is ACTIVE, what is happening with regards to neurotransmitters?
Neurotransmitter release decreases in proportion to the amount of light
The off-center bipolar cell [hyperpolarizes/depolarizes] the off-center ganglion cell, inhibiting action potential.
Hyperpolarizes
The on-center bipolar cell [hyperpolarizes/depolarizes] an on-center ganglion cell, exciting it and increasing the probability of action potential.
Depolarizes
Light in the surround of an on-center bipolar cell [hyperpolarizes/depolarizes] it, inhibiting on-center ganglion cells.
Hyperpolarizes
This type of cell would fire the most action potentials when light hit the surround of its receptive field.
Off-center
An integrating neuron is generally found in this.
Central Nervous System
Integrating neurons are also called ____.
Interneurons
Review light. light-dark, and dark bar cells.
Okay
True or False: A horizontal bar of light in any position in the visual field can cause stimulation.
True; a bar at an angle of orientation different from the preferred angle is MUCH less stimulatory
True or False: Critical Flicker Fusion (CFF) allows animals to see MORE QUICKLY than humans.
False. Animals can see more information in a smaller amount of time, allowing them to see in "slow motion" compared to humans.
The adrenal cortex secretes these hormones:
Aldosterone, androgens, glucocorticoids. (Steroids)
The adrenal medulla secretes these hormones:
Epinephrine, norepinephrine, and dopamine. (Catecholamines)
The anterior pituitary gland secretes these hormones:
Prolactin, growth hormone, melanocyte-stimulating hormone, adrenocorticotropic hormone (ACTH), Thyroid-stimulating hormone (TSH), Lutenizing hormone, y-lipotropin and B-endorphin
Bone Osteoblasts secrete this hormone:
Osteocalcin
Fat secretes these hormones:
Leptin and adipokines
The GI tract secretes these hormones:
Stomach: Gastrin and Ghrelin
Small intestine: secretin, cholecystokinin, glucagon-like peptide, somatostatin, motilin
Gonads secrete these hormones:
Estrogens, progesterone, inhibin, activins, relaxin, Mullerian-inhibiting hormone, androgens
The heart secretes this hormone:
Atrial natriuretic peptide
The hypothalamus releases these hormones:
Releasing and inhibiting hormones; Corticotropin-releasing hormone (CHR), Thyrotropin-releasing hormone (TRH), Growth hormone-releasing hormone (GHRH), Somatistatin, Gonadotropin-releasing hormone (GnRH), Gonadotropin-inhibiting hormone (GnIH), Dopamine, Melanocyte-stimulating hormone-inhibiting hormone, Ghrelin
Kidneys release these hormones:
Renin, Erythropoietin, Calcitrol
The liver releases these hormones:
Angiotensinogen, insulin-like growth factors
The pancreas releases these hormones:
Insulin, glucagon, and somatostatin
Parathyroid gland releases this hormone:
Parathyroid hormone
The pineal gland releases this hormone:
Melatonin
The placenta releases these hormones:
Estrogens and progesterone, chorionic gonadotropin, relaxin, placental lactogen
Posterior pituitary gland:
Vasopressins (AHD), Oxytocin
The skin releases:
Vitamin D
The thymus gland releases:
Thymosin and thymopoietin
The thyroid gland releases:
Thyroid hormones and calcitonin
Review chart of vertebrate nervous system division chart
Okay
The autonomic nervous system has these two divisions:
Sympathetic and parasympathetic
This nervous system regulates digestive organs, receiving both sympathetic and parasympathetic inputs
Enteric nervous system
The sympathetic division of the ANS has these effects on the body, preparing it for physical activity.
-Increases heart rate
-Opens airways
-Break down glycogen and fat stores
-Dilate vessels supplying skeletal muscles
-Dilate pupils
(See figure 15.11)
The parasympathetic division of the ANS has these effects on the body, which are general housekeeping functions.
Digestion and excretion (See figure 15.11)
Nicotinic and muscarinic receptors are this type.
Cholinergic
Nicotinic receptors are [ionotropic/metabotropic] and are found on post-ganglionic cell bodies and dendrites.
Ionotropic, procude EPSP
Muscarinic receptors are [ionotropic/metabotropic] and are found on effector cells of the parasympathetic system
Metabotropic, triggers signal cascades and second messengers leading to IPSP
Adrenergic receptors are found on these cells and are GPCR (G Protein coupled receptors)
Effector cells of the sympathetic system
The forebrain is divided into these two parts:
Telencephaon and Diencephalon
The midbrain is also known as:
Mescenphalon
The hindbrain is divided into these two parts:
Metencephalopn and myelencephalon
The forebrain has the following areas:
Telencephalon: Cerebral cortex, hippocampus, basal ganglia, limbic system
Diencephalon: Thalamus and hypothalamus
The midbrain has the following areas:
Mesencephalon: Superior and inferior colliculus
The hindbrain has the following areas:
Metencephalon: Cerebellum and pontine motor nuclei
Mylencephalon: Medulla oblongata
The function of the cerebral cortex is:
Higher sensory, motor and integrative functions
Reminder: It is located in the forebrain's telencephalon.
The function of the hippocampus is:
Learning and memory
Reminder: It is located in the forebrain's telencephalon.
The function of the basal ganglia is:
Motor control
Reminder: It is located in the forebrain's telencephaon
The function of the limbic system is:
Emotion control.
Reminder: It is located in the forebrain's telencephalon.
The function of the thalamus is:
Major sensory relay.
Reminder: It is located in the forebrain's diencephalon.
The function of the hypothalamus is:
Homeostatic and endocrine regulation, as well as circadian clock regulation.
Reminder: It is located in the forebrain's diencephalon.
The function of the superior colliculus is:
Visual integration.
Reminder: It is located in the midbrain's mesencephalon.
The function of the inferior colliculus is:
Auditory integration.
Reminder: It is located in the midbrain's mesencephalon.
The function of the cerebellum is:
Motor coordination.
Reminder: It is located in the hindbrain's metencephalon.
The function of the pontine motor nuclei is:
Descending motor control.
Reminder: It is located in the hindbrain's metencephalon.
The function of the medulla oblongata is:
Autonomic and respiratory control.
Reminder: It is located in the hindbrain's myelencephalon.
This system regulates and coordinates distant organs through hormone secretion.
Endocrine system
These are signal molecules that are delivered to targets through the blood/circulatory system.
Hormones
The three classes of hormones are:
Steroids, peptides, and amines
These hormones are six carbon chains.
Steroids
This type of hormone is genetically encoded and hydrophilic.
Peptides
True or False: The cerebrospinal fluid is another name for brain extracellular fluid.
False
The part of the vertebrate nervous system that sends information to the central nervous system is the:
Sensory/afferent
Receptors of the autonomic nervous system that generally initiate EPSPs are:
Nicotinic
The part of the brain that is involved in higher order integration and reasoning is the _____
Cortex
The cortex is found in the _____
forebrain
This type of hormone is derived from amino acids such as tyrosine and tryptophan.
Amines
Dopamine, epinephrine, and norepinephrine are all this type of amine/hormone.
Catecholamine
Thryoxine and Triiodothyronine are both types of:
Thyroid hormones. They are also hydrophobic and containe iodine
Melatonin, a hydrophillic hormone, is derived from this amino acid:
Tryptophan.
These types of hormones can diffuse through cell membranes and alter gene expression.
Steroids and Thyroid hormones
The only type of hormones that are genetically encoded are:
Peptides
Read over "properties of hormones" chart. Table 16.1, slide 21.
Okay
This is a method of control in which too little of a hormone promotes production and too much of a hormone inhibits its production.
Negative feedback
This method of control is when hormones are produced in response to a specific stimulus.
Neuronal
This method of control occurs when the secretion of hormones fluctuates as a function of time.
Biorhythms
What are three ways in which the anterior pituitary is controlled?
Electrolytic lesions in the hypothalamus (TSH, ACTH, FSH, LG, and GH decrease, prolactin increases), Stimulating electrodes in the hypothalamus (TSH, ACTH, FSH, LH, and GH increase, prolactin decreases), cutting the stalk of the pituitary (TSH, ACTH, FSH, LH and GH decrease, prolactin increases)
Read study by Roger Guillemin and Robert Burgus about sheep brains
Okay
True or False: The hypothalmus controls secretions of hormones from the anterior pituitary, and all are peptides except dopamine.
True
How are neurosecretory cells controlled?
Neural input and negative feedback
Thyrotropin is responsible for:
Metabolism and growth
TSH -> Thryoid gland -> Thyroid hormones -> Metabolism and Growth
Adrenocorticotropin is responsible for:
Stress response and metabolic actions
ACTH -> Adrenal Cortex -> Glucocorticoids -> Stress response and metabolic action
Growth Hormone is responsible for:
The growth of many tissues and metabolic actions
Liver -> Insulin-like growth factors -> tissue growth
Muscles and fat -> Metabolic actions
MSH (melanocyte-stimulating hormone) in some animals is responsible for:
Skin darkening in amphibians, reptiles and fish
Prolactin is responsible for:
Mammary glands of mammals -> growth during pregnancy and milk production
Various vertebrates -> Reproduction, water and ion balance, caring for young
Gonadotropin is responsible for:
LH -> gonads -> sex, hormone production and secretion
FSH -> gonads -> sperm production in males, follicle development and secretion in females
Vasopressin (mammals) and vasotocin (non-mammals) is responsible for:
Osmoregulation/water retention and vasoconstriction
Oxytocin is responsible for:
Social bonding, uterus contractions, milk ejection
Read about/watch video on anti-diuretic hormone
Okay
Thyroxine, produced by the thyroid gland, functions to:
Maintain normal cellular metabolism, promote GH release, increase catabolism of carbs and lipids, protein anabolism, nervous system activity stimulation
True or False: triiodothyronine functions the same way as Thryoxine, but it is LESS potent.
False, it is more potent.
The thyroid gland produces one peptide hormone (the others are thyroid hormones). It is:
Calcitonin
Calcitonin's function is:
Homeostasis of blood calcium when it is too high; reduces bone breakdown and increases loss of calcium in urine through kidneys
Parathyroid hormone
Regulation of blood calcium when it is too low.
** Antagonist of Calcitonin**
These hormones are involved in stress responses:
Glucocortocoids and catecholamines, found in the adrenal glands
Mineralcorticoids have this function:
Regulate mineral electrolyte homeostasis
Vasopressin (pituitary gland) and Aldosterone (adrenal cortex) cause increased water absorption (kidneys) and increased Na+ absorption (kidneys). Fluid retention is increased, as well as blood volume and blood pressure
Okay
Pancreatic islets are called:
Islets of Lagerhans
Islets of Lagerhans secrete three groups of cells:
Alpha (glucagon), Beta (insulin), and Delta (somatostatin)
Glucagon has these functions:
-Prevents hypoglycemia
-Stimulates liver to break down glycogen
-Stimulates break down of fats
-Stimulates liver to convert amino acids and fats into glucose
Insulin has these functions:
-Prevents hyperglycemia
-Stimulates liver to convert glucose into glycogen
-Inhibits gluconeogenesis in the liver
-Promotes facilitated diffusion of glucose into cells with insulin receptors
-Promotes protein synthesis
-Promotes synthesis of fats by adipose cells
This is classified as something that is a threat to homeostasis.
Stress
This is when environments, external or internal, approach "danger" zones.
Range of acceptability
This allows an organism to "cope" with stressors and return to a homeostatic state
Stress response
During periods of stress, these bodily functions increase:
Activity, blood flow, heart rate, and energy/glucose availability
During periods of stress, these bodily functions are suppressed:
Reproduction, immune system, appetite
REVIEW FIGURE 16.12 AND NOTES
Okay
Acute CORT inhibits:
Cell division, protein synthesis, and immune system functions (if present AFTER immune response)
For example, cortisone creams and shots to reduce inflammation
Acute CORT enhances:
Blood pressure, cardiac output, immune system (if present BEFORE immune response to allow the body to prepare for damages), free glucose
Some activational effects of hormones are:
They are not devlopmental, they're seen during or soon after hormone release, they are temporary, they can control hunger, blood calcium, and water.
Some organizational effects of hormones are:
They occur during critical developmental periods, they irreversibly alter behavior and physiology, Example: secondary sexual characteristics
increase anxiety, impair parental behavior, decrease aggression toward intruders, decrease memory and learning, increase probability of psychological problems. (Abused become abusers)
Nazca boobies perform this when food is scarce
Siblicide
These are non-breeders or failed breeders, both male and female, that harass chicks in a variety of ways.
Non-Parental Adult Visitors (NAVs)
Three types of NAV behaviors include:
Aggressive (51%), Affiliative (46.3%), and Sexual (12.2%)
This is responsible for gonad growth and development, as well as the development of sexual secondary characteristics
HPG axis
Release of this hormone triggers the production of sex steroids in the gonads.
LH
TRUE OR FALSE:The anterior pituitary produces releasing and inhibiting hormones
False
TRUE OR FALSE: The anterior pituitary is glandular and releases hormones, while the posterior pituitary is neuronal and releases neurohormones
True
True or False: Calcitonin INCREASES circulating [Ca2+]
False, it REDUCES circulating [Ca2+]
This is produced by adipose cells and it reduces hunger.
Leptin
The first response to a stressor is driven by:
Sympathetic stimulation
Pick the false statement about CRH released by the hypothalamus:
A. Inhibits sympathetic stimulation of adrenal glands
B. Enhances memory formation of stressful events
C. Triggers production and release of ACTH from the anterior pituitary
D. Inhibits reproduction
E. Both A and D
Both A&D
True or False: Both early and late responses to an acute stressor cause an increase in blood glucose
True
The downward trend in circulating CORT seen after 25 minutes in the capture-restraint test is caused by:
CORT inhibiting the release of CRH
True or False: The Fence control group in the exclosure experiment was done to determine if NAV events cause a stress response.
False
This is produced by granulosa cells and inhibits the release of FSH by the anterior pituitary.
Inhibin
The brain structure that regulates circadian rhythms is the:
Suprachiasmatic nucleus