Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
26 Cards in this Set
- Front
- Back
- 3rd side (hint)
|
What are the building blocks of proteins |
Amino acids |
|
|
|
The three-dimensional structure of protein is strongly influence by |
Chemical structure of amino acids |
|
|
|
One unpopular feature of amino acids is that they are ___________? |
Important intermediates in metabolism |
|
|
|
Which isomer is normally found in proteins |
L-isomer |
|
|
|
When fully protonated a simple mono-amino mono-carboxylic ∞-amino acid is what type of acid? |
Diprotic acid |
|
|
|
Non-polar amino acids are all_______? |
Hydrophobic |
|
|
|
_________&_________ are non polar amino acids found buried or immersed in globular protein |
Phenylalanine and tryptophan |
P&T |
|
|
Proline has its side chain (R) bonded to it's backbone nitrogen as well, it is called an______ acid |
Imino |
|
|
|
List all non polar amino acids |
Glycine, Alanine, Valine, Leucine, Isoleucine, Methionine, Phenylalanine, Tryptophan, Proline. |
|
|
|
_______ is phenylalanine with an added OH group. It is polar and slightly acidic. It can play an important catalytic role in the active sites of some enzymes. |
Tyrosine |
|
|
|
List all polar amino acids |
Serine, Threonine, cysteine, Glutamine, Asparagine, Tyrosine.q |
|
|
|
An amino acid, which is not too polar and also capable of forming di-sulphide bridge via sulphur bonds is called _______? |
Cysteine |
|
|
|
Histidine play an active role in __________________ which explains why it is always found in active sites. |
Mechanism of enzymes |
|
|
|
________ is responsible for the formation and maintenance of tertiary(folded) structure of many protein |
Di-sulphide bridge |
|
|
|
_______ is known for forming di-sulphide bond |
Cysteine |
|
|
|
Glutamate and aspartate confer a _______ charge on protein where they are present? |
Negative(acidic) |
|
|
|
______ is important in the formation of tertiary (folded) structure in protein |
Di-sulphide bridge |
|
|
|
_______&______ have pk of about 10, are always positively charged at neutral pH? |
Lysine and arginine |
|
|
|
_______ plays an important role in catalytic mechanisms of enzymes which explains why it is always found in many active sites |
Histidine |
|
|
|
All amino acids are alpha amino except________? |
Proline |
|
|
|
All amino acids are chiral except_________? |
Glycine( the simplest amino acid) |
|
|
|
At pH of 7.0 ___,____&____ test positive (Dextrtrotary) to optical activity |
Ala, Ile and Glu(glutamate) etc. |
|
|
|
At pH of 7.0 ___,____&____ test negative (levorotary) to optical activity |
Phe ,leu, trp |
|
|
|
All amino acids absorb in? |
Infrared region except Phe, Trp and Tyr which absorb in UV |
|
|
|
_______ is characteristic of each protein residue and it's high resolution measurement can be used to explain the three dimensional structure of protein |
NMR spectra |
|
|
|
Non-essential amino acids are synthesized invivo? T or F |
T |
|
