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22 Cards in this Set

  • Front
  • Back
ACTH stimulates the release of which hormones from the adrenal cortex?
mainly cortisol and androgens
What effect will long term, high dose hydrocortisone use have on ACTH levels? Increase, decrease or no change
decrease
What effect will long term, high dose hydrocortisone use have on the adrenal cortex? hypertrophy, atrophy or no change
atrophy
hydrocortisone has which type of effect? mainly glucocorticoid, mainly mineralocorticoid, or both
both
fludrocortisone has which type of effect? mainly glucocorticoid, mainly mineralocorticoid, or both
mineralocorticoid
hydrocortisone has which type of effect? raise blood glucose levels or reduce blood glucose levels
raise
fludrocortisone has which type of effect? increase Na retention or decrease Na retention by the kidney
increase Na retention by the kidney
fludrocortisone has which type of effect? increase K excretion or decrease K excretion by the kidney
increase K excretion by the kidney
What is Addison’s disease?
primary adrenal insufficiency
What is the main cause of secondary adrenal insufficiency?
long term glucocorticoid use
Addison’s disease will mainly decrease the levels of which hormones?
Cortisol, androgens and aldosterone
Secondary adrenal insufficiency will mainly decrease the levels of which hormones?
Cortisol and androgens
What is the main treatment for Addison’s disease?
hydrocortisone, fludrocortisone if still hyperkalemic
What is the main treatment of secondary adrenal insufficiency from a nonfunctioning pituitary?
hydrocortisone
What hormonal changes occur with congenital adrenal insufficiency?
reduced cortisol, aldosterone and elevated androgens
What effect will congenital adrenal insufficiency have on ACTH levels?
increase
What is the main treatment of congenital adrenal insufficiency?
hydrocortisone
What happens to endogenous cortisol, androgen and aldosterone levels with hydrocortisone treatment of congenital adrenal insufficiency?
cortisol and aldosterone stay about the same, androgen levels decrease
What is the main treatment for an acute adrenocortial insufficiency during surgical procedures?
hydrocortisone
What are ACTH levels like with a pituitary adenoma that causes Cushing’s syndrome?
increased
In a patient with Cushing’s syndrome, a low dose of dexamethasone will have what effect on endogenous cortisol levels?
no effect
What is the main clinical use of mitotane?
Cushing’s disease