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54 Cards in this Set

  • Front
  • Back

Functions of Bone and Skeletal Tissue

support


covering and protection


movement and leverage


storage

Minerals Stored in Bones and Skeletal Tissue

calcium


phosphate (for ATP)

Fat Stored in Bones and Skeletal Tissue

yellow marrow

Heavy Metal Toxins Stored in Bones and Skeletal Tissue

lead


mercury


*storing them here keeps these toxins away from nervous tissue


This is a good thing!

Hematopoesis

formation of blood cells (RBC, WBC, Platelets)


red marrow

Compact Vs. Spongy Bones

Compact: Solid


Spongy: Beams (Lots of spaces)

Long Bone Examples

Humerus, Femur

Short Bone Examples

Wrist, Ankle

Flat Bone Examples

Sternum, Ribs, Top of Skull

Irregular Bones

Usually a combo and short and flat


Ex. vertebra, temporal bone

What the Skeleton is Made Out of

Bone and Cartilage

Axial "Axis" Region

Skull, Spine, Ribs, Sternum


Main axis of body

Appendicular "Appendages" Region

Hips, Legs, Arms


"Added On"

Osteogenic Cells

Stem

Osteoblast Cells

Make Bone


Haversian System


Look like tree trunks

Osteocyte Cells

In Mature Bone


In spaces called Lacunae

Osteoclast Cells

Breaks down bone tissue


Large, multinucleate

Diaphysis

Long Bones


Shaft


Tube of Compact Bone


Medullary Cavity with Yellow Marrow

Epiphyses

Long Bones


Ends (Proximal and Distal)


Superficially is Compact Bone


Deep is Spongy Bone



Epiphyseal Line

Remnant of Epiphyseal Plate (Metaphysis)


Growth Plate

Articular Cartilage

Hyaline Cartilage


Joint Cartilage

Connective Tissue Membranes

Made of Dense Irregular C.T. (Collagen)


Perforating (Sharpey's) Fibers


Periosteum and Endosteum

Perforating (Sharpey's) Fibers

C.T. Membrane


Connects to Bone

Periosteum Vs. Endosteum

Periosteum: Outside C.T. Membrane


Endosteum: Inside C.T. Membrane

Flat, Short, Irregular Bone Structure

Superficially is Compact


Deep is Spongy


Same Membranes (Periosteum and Endosteum)

Red Marrow

Mostly in Short and Flat Bones


Hematopoesis


Found in Axial Skeleton and Proximal Appendicular Skeleton


What you get during Bone Marrow Transplant

Compact Bone

Osteons


Other Lamellae

Lacunae

Connected Via Canaliculi

Canaliculi

Through layers called lamellae

Lamellae

Surround Central Candais

Central Candais

With blood vessels, connect via perforating canals to bone surface

Circumferential Lamellae

Outer Surface of Bone

Interstitial Lamellae

Between Osteons

Spongy Bone

No osteons


Made up of trabeculae "beams" of bone


-Usually 2 osteocytes thick


-Make bone lighter while maintaining strength

Organic Matrix

Carbon Based


Collagen Fibers mostly (run in diff. directions)


GAGs


Strength: Tensile-Collagen


Osteoid: laid down (made) 1st by Osteoblasts

Inorganic Matrix

Made of Calcium Salts


ex. Ca10(PO4)6(OH)2 Hydroyapatite


Strength: Compression

Enddochondral Ossification

"within cartilage bone formation"


(long and short and some irregular)



Hyaline Cartilage Model

growth changes occur at 3rd month of development

Primary Ossification Center

Periosteal bud invades cavities forming


-Contains osteoblasts and blood vessels


-bone laid down is spongy bone


-diaphysis eventually hollowed out (medullary cavity)

Secondary Ossification Center

Periosteal buds invades epiphyses


Around time of birth

Intramembranous Ossification

"inside membrane bone formation"


(flat bones and parts of irregular)


start with fibrous membranes (dense irregular C.T.)


within membrane, osteoblasts develop and make bone


forms ossification center


osteoid organic matrix (collagen)


laid down first spongy bone

Intrmembranous Ossification at Edge of Membrane

osteoblastic layer develops


laid down compact bone

Bone Growth in Length, Long Bones

Metaphysis/Growth Plate


-Cartilage grows towards epiphysis


-Cartilage taken over by bone on diaphysial side


Process continues until end of adolescence


-Puberty: Increase in sex hormones


-Stimulates cartilage and bone growth


-Eventually bone overtakes cartilage, growth stops

Appositional Growth for All Bones

"wider/larger"


Compact bone tissue added outside


Compact tissue reabsorbed inside


Spongy bone added inside

Hormones Involved in Bone Growth

Growth hormone: Pituitary Gland


Sex hormones: testosterone and estrogen


Thyroid: metabolism

Bone Remodeling

Bone is living tissue that is constantly remodeling

Osteoblast Vs. Osteoclast Activity

Bone forming cells Vs. Bone breakdown cells

Remodeling Control

Body's need for calcium in blood


Stresses put on bone


Hormones important in remodeling

Body's Need for Calcium in Blood

many uses for Calcium (nerve signaling, muscle contraction, blood clotting)


not enough Calcium in blood=Calcium taken from bone

Stresses Put on Bone

Wolff's Law: Bone is deposited in response to stress on bones


Fat people and muscular people have stronger bones


Muscle attachments make projections=processes on bones

Hormones Important in Remodeling

Sex Hormones: girls=hips flatten, wider; growth spurt in boys and girls


Growth Hormones: stronger bones and muscles

Factors that Decline with Aging that Contribute to Osteoporosis

Decrease in Growth Hormones

Decrease in Sex Hormones


Decrease in Exercise (Stress on Bones)


Why are women more likely to develop Osteoporosis?

Large decrease in the Sex Hormones during Menopause

How to Reduce Risk of Osteoporosis

Exercise, Calcium rich diet


*Especially important to build up bone mass when young