• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

Card Range To Study

through

image

Play button

image

Play button

image

Progress

1/62

Click to flip

Use LEFT and RIGHT arrow keys to navigate between flashcards;

Use UP and DOWN arrow keys to flip the card;

H to show hint;

A reads text to speech;

62 Cards in this Set

  • Front
  • Back
The walls of arteries have 3 layers of tissue surrounding the lumen. What are they?
inner = endothelium, basement membrane, elastic lamina
middle = smooth muscle and elastic tissue
outer = elastic and collagen fibers
small arteries
arterioles
Sympathetic fibers of the autonomic nervous system innervate _____ muscle.Increase in sympathetic stimulation causes ______
vascular smooth muscle; vasoconstriction.
Decrease of sympathetic stimulation causes _____
vasodilatation
capillaries connect what to what?
arterioles to venules
capillary walls are ______ and are made of
transparent; endothelium and basement.
Because of the thinness of these walls, exchange between the blood and the body cells are possible.
venules are similar in structure to _____; their walls are only slightly _____ than those of capillaries
arterioles
thicker
veins are structurally similar to _____; but what is different?
arteries; vein's middle and inner layers are thinner with much less elastic tissue.
In some veins, the inner layer folds inward to form _____ that do what?
valves; that prevent the backflow of blood.
Weak venous valve may cause ______
varicose
arteries carry blood ____ the heart and toward _______ in the _______
away from; toward capillaries in the tissue.
arterioles play a key role in doing what?
regulating blood flow from arteries into capillaries.
Because capillaries are numerous and their walls are very thing and blood flows so slowly, ______ can occur
capillary exchange

for ex., oxygen, carbon, dioxide, glucose, amino acids, and hormones enter and leave capillaries by diffusion
all plasma solutes except _____ pass easily across most capillary walls
proteins
________ can make the fluid move out and _________ can make the fluid move in.
capillary blood pressure
blood colloid osmotic pressure
blood colloid osmotic pressure is maintained by
concentration of solutes, especially proteins.
In some diseases, such as nephrotic syndrome, cirrhosis of the liver, decreased _________ causes ________
plasma protein; edema
venules and veins drain __________ and return blood to the ________
capillaries in the tissues; the heart
The blood flowing back to the heart through systemic veins occurs due to the pressure generated by ?
contractions of left ventricle
how much blood flow in venules vs. right ventricle?
16 mm/Hg in venules and 0mm Hg in right ventricle.
By the time blood leaves the capillaries and moves into veins, it has lost a great deal of _______
pressure
clinically, blood samples are obtained from a _____ because ?
vein; pressure is low and many of the veins are close to the skin surface.
What is a pulse?
the alternate expansion and elastic recoil of an artery after each contraction of the left ventricle.
What is the most common place to feel the pulse?
the radial artery at the wrist
What is the second most common place to feel the pulse?
common carotic artery next to the voice box on the neck (used during cardiopulmonary resuscitation)
Normal pulse rate
same as heart: 60-100 times per minute in adult at rest, tho most people are around 70-80.
Tachycardia pulse rate
over 100 beats/min

can be seen in exercise, fever, or hyperthyroidism
bradycardia rate
under 60 beats/min

can be seen in sick sinus syndrome, hypothyroidism, or some normal people.
What is blood pressure (BP)?
the force exerted by the blood against the walls of vessels

product of the output of the heart and the resistance in the vessels.
The output of the heart is influenced by what 2 things?
1. strength of the contraction of the heart
2. total blood volume
The resistance in the vessels is affected by what 3 things?
1. vasomotor change
2. elasticity of blood vessels
3. viscosity of the blood
Blood pressure is regulated by what?
CV (cardiovascular) center and some hormones.
What is the CV center?
medulla oblongata
the higher brain regions:
including cerebral cortex, limbic system, and hypothalamus.
The sensory receptors; proprioceptors
in skeletal muscles, tendons, and labyrinth provide impulses during physical activity, or reaction to some stimulations from environment
baroreceptors
pressure receptors located in aorta, internal carotid arteries, and other large arteries in neck and chest. They send impulses continuously to CV center to regulate the BP thru autonomic nerve system.
chemoreceptors
located in two carotid bodies in common carotid arteries and one aortic body in the arch of the aorta. Monitor blood levels of O2, CO2, and H+ and send the impulses to CV center during hypoxia, acidosis, and hypercapnia to produce vasoconstriction and increase of BP.
Several hormones help regulate blood pressure, which include (4)
1. Raa: Renin-angiotensin-aldosterone system: when blood volume falls or blood flow to the kidney decreases, certain cells in the kidneys secrete rennin and activate Raa system. angiotensin II causes vasoconstriction and aldosterone increases Na+ and water reabsorption. Both ELEVaTE BP
2. Epinephrine and norepinephrine: in response to sympathetic stimulation, adrenal medulla releases these hormones, which increase cardiac output by increasing the rate and force of heart contractions; they also cause vasoconstriction of arteries and veins in the skin and abdominal organs to INCREaSE BP.
3. antidiuretic hormone (adh), aka vasopressin, secreted by posterior pituitary and causes vasoconstriction and INCREaSES BP.
4. atrial natriuretic peptide (anp): released by the cells in the atria of the heart, anp LOWERS blood pressure by causing vasodilatation, promoting the loss of salt and water in the urine.
What lowers BP?
anp (atrial natriuretic peptide)
what instrument measures blood pressure?
sphgmomanometer.

pump 170-200 mmHg.
First sound heard when reading blood pressure
systolic pressure

occurs during heart muscle contraction
last sound heard when reading blood pressure
diastolic pressure

occurs during relaxation of the heart muscle.
Normal range bp:
<140/90 mmHg and >90/60 mmHg. avg level in young adult at rest is about 120/80mmHg.

Bp > or = 240/90 mmHg indicated hypertension and BP < or = 90/60 mmHg indicates hypotension
all systemic circulation branches from
aorta
aorta, which arises from the ________ and can be divided into 4 parts:
arises from the left ventricle of the heart, divided into:
1. ascending aorta: gives off two coronary arteries and which supply oxygenated blood to the cardiac muscle
2. arch of the aorta: the branches supply the head and neck and the organs therein and both upper extremities.
3. thoracic aorta: the branches supply the chest wall, organs in the chest, such as esophagus, bronchi, pericardium, and plurae, etc .
4. abdominal aorta: the branches supply organs in abdomen, such as stomach, small and large intestine, liver, spleen, pancreas, adrenal glands, and kidneys, etc. Divided also into two common iliac arteries and their branches, which supply both lower extremities.
all the systemic veins empty into the ___, _______, or ______, which in turn empty into the __________
superior vena cava, inferior vena cava, or coronary sinus.....right atrium.
When deoxygenated blood returns to the heart from the systemic route, it is pumped out of the _______ ventricle through pulmonary trunk and two _________ into the __________. Here, it loses __________ and picks up __________.
pulmonary arteries
lungs.
loses carbon dioxide and picks up oxygen.
In pulmonary circulation, oxygenated blood returns through _________ through ______
left atrium
through 4 pulmonary veins.
In pulmonary circulation, _____ carry deoxygenated blood and _____ carry oxygenated blood
pulmonary arteries
pulmonary veins
Some chronic lung or heart disease may cause deficiency of oxygen of the body and _______ appears
cyanosis
A vein that carries blood from one capillary network to another is called a
portal vein
The hepatic portal vein, formed by the union of what 3 veins?
splenic, superior, and interior mesenteric veins.
Hepatic portal vein receives blood from capillaries of ______ and delivers it to ______
digestive organs
capillary-like structures in the liver called sinusoids.
During hepatic portal circulation, liver receives oxygenated blood from the
systemic circulation via the hepatic artery
Ultimately, all blood leaves the sinusoids of the liver through the _____ which drain into the ?
hepatic veins, which drain into the inferior vena cava
Some liver disease like cirrhosis of liver may cause ______ which can lead to ?
hypertension of portal vein, which results in ascites, splenomegaly, and bleeding of esophageal varications, etc.
Shock is?
a failure of the cardiovascular system to deliver enough oxygen and nutrients to meet cellular metabolic needs. It does not constitute a disease, which s a clinical syndrome of acute circulatory failure induced by many causes, and the pathogenesis is complicated.
Common types of shock include these 5 things:
1. cardiogenic shock: also called pump failure, as occurs in myocardial infarction (heart attack)
2. infectious shock: is is caused by infection of microbes, such septicemia resulting from pneumonia, pyelonephrities, etc. which is also called septic shock
3. hypovolemic shock: decreased blood volume may be caused by acute hemorrhage (injury, upper gastrointestinal bleeding, etc.) or severe dehydration
5. Anaphylactic shock: is a severe allergic reaction caused by injection of some drugs like penecillin, or serum reagents, etc.
6. neurogenic shock: due to injury or ischemia of brain or spinal cord, which cause inhibition of vasomotor center and loss of vascular strength
common clinical features of shock include:
low blood pressure (systolic pressure < 90 mmHg), rapid heart and pulse rates, cool and pale skin, sweating, oliguria, etc. Clinically acute and severe condition.
Hypertension
defined as persistently high blood pressure.
Hypertension can be divided into two things:
essential or secondary

about 5% patients with secondary hypertension are caused by some primary diseases (renal disease and endocrine disease, etc.)

90-95% patients with essential hypertension are etiologically unknown. Pathogenesis may be related to genetic factor, diet (esp high Na intake), obesity, endocrine and nervous factors, etc.

can also cause complications such as coronary artery disease, stroke, and hypertensive nephropathy
How do you lower the risk of hypertension?
Lose weight, limit alcohol intake, exercise, reduce intake of Na and increase intake of K, Ca, and Mg, do not smoke, and manage stress