Osteitis Fibrosa Cystica is closely interrelated to hyperparathyroidism and therefore, the bone disease’s epidemiology is similar to the latter. As of late, there have been far less reports of OFC than in the 1950s. It is primarily detected in Asian countries. A recent study in India shows that the occurrences of the disease are parallel to the reports of first world countries back when OFC was slowly becoming rare. The disease does not appear in one gender more often than the other, but there are more cases among people younger than 50 years old.
Etiology OFC occurs as a result of untreated hyperparathyroidism. Four parathyroid glands that are located in the neck are responsible for producing the parathyroid hormone that helps regulate the levels of calcium, phosphorous, and vitamin D throughout the body. Abundant amounts of the parathyroid hormone will cause osteoclasts to become hyperactive and weaken the bone by breaking it down to allow calcium to leave the bone and fuse into the bloodstream. Without the necessary minerals, the bone will not function properly so tissue will form to replace the bone’s lost …show more content…
Blood tests may also show that parathyroid hormone levels surpass the normal amounts that vary from 10 to 55 pg/mL. X-rays may show delicate thinning teeth, brown tumors, or depictions of any bones that show signs of complete or partial fractures, which can be most easily detected in the fingers since they are more often than not the first areas to show OFC symptoms. Nuclear imaging can detect the cysts surrounded by osteoclasts. After identifying any damaged bone tissue, the fine needle aspiration process can be carried out by taking a sample of the lesion’s cells. It is controversial if the aforementioned process should be used because of the health risk that the needle may negatively interfere with the
Etiology OFC occurs as a result of untreated hyperparathyroidism. Four parathyroid glands that are located in the neck are responsible for producing the parathyroid hormone that helps regulate the levels of calcium, phosphorous, and vitamin D throughout the body. Abundant amounts of the parathyroid hormone will cause osteoclasts to become hyperactive and weaken the bone by breaking it down to allow calcium to leave the bone and fuse into the bloodstream. Without the necessary minerals, the bone will not function properly so tissue will form to replace the bone’s lost …show more content…
Blood tests may also show that parathyroid hormone levels surpass the normal amounts that vary from 10 to 55 pg/mL. X-rays may show delicate thinning teeth, brown tumors, or depictions of any bones that show signs of complete or partial fractures, which can be most easily detected in the fingers since they are more often than not the first areas to show OFC symptoms. Nuclear imaging can detect the cysts surrounded by osteoclasts. After identifying any damaged bone tissue, the fine needle aspiration process can be carried out by taking a sample of the lesion’s cells. It is controversial if the aforementioned process should be used because of the health risk that the needle may negatively interfere with the