Causes Of Alzheimer's Disease

Decent Essays
The protein found from the DNA sequence is called Presenilin-2. This gene is also called PSEN2. PSEN2 is also a coding gene. When there is a gene mutation in the Presenilin-2 gene, Alzheimer’s can occur. PSEN2 helps to process proteins. These proteins transmit chemical signals from the membrane to the nucleus. Genes are then activated. These genes help with cell growth and the maturing of cells. At least 11 mutations to the PSEN2 gene have lead to and early onset of Alzheimer’s disease. Presenilin is responsible for about 5% of Alzheimer’s diseases. PSEN2 is a rare cause for Alzheimer’s. There have been 18 mutations of PSEN2 reported but none have been proven pathogenic. Alzheimer’s is a disease that causes progressive mental deterioration.

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