Coagulation system

Hemophilia is a medical condition in which the ability of the blood to clot is severely reduced causing the sufferer to bleed severely from even a slight injury. There are four types of Hemophilia which are Hemophilia A-Also called classic hemophilia, it is four times more common than Hemophilia B, and it occurs when factor VIII levels are deficient, Hemophilia B-Also called christmas disease, it occurs when factor Xi levels are deficient, Hemophilia C-It occurs when facts of XI levels are…

comes in contact with agents which activates the contact factors. PTT assesses intrinsic and common pathway of coagulation. Prothrombin time ( PT) measures the time needed for plasma to form a clot in the presence of tissue factor. PT evaluates extrinsic and common pathway of coagulation (Zehnder, 2017). In Hemophilia, the deficient factors are related to the intrinsic cascade of coagulation, therefore PTT is prolonged and abnormal. b. In which gender is this disorder common and why? • This…

Disseminated intravascular coagulation is not an illness. It is in fact a life-threatening blood disorder. This disorder is characterized by excessive clotting or bleeding. This is due to widespread fibrin formation or fibrinolysis. Fibrinolysis is the dissolution of fibrin in the blood stream. With DIC, the blood can clot in one location and hemorrhage in another location at the same time. Disseminated intravascular coagulation can cause fibrin deposits in small or medium blood vessels. This…

Many other diseases have also become a concern for hemophilia A patients. As life expectancy for these patients has increased so has their chance of developing bone diseases. Due to the danger of injuring one’s self most hemophilic patients don’t exercise and get outside enough, resulting in low vitamin D levels. The results of low vitamin D, lack of exercise, and bleeding in joints can lead to development of osteoporosis in hemophilia A patients. One study of children (18 and younger) found…

Hard dreamer age 25 male a case of frequent disruption to studies & parents under emotional & financial stress. As a kid “he cuts his small toe when he was one years old resulting in an unusual bleed,” (Ramchander, 2009). Then he starts “bleeding frequently from different sites like his gums, nose & ears,” (Ramchander, 2009). Three years later he bleeds from his forehead & hip after a fall, he experiences a major bleed in the urinary tract, & lastly his right knee is swollen making his movements…

A wise American poet, Roger Zelazny, once said “The power to hurt has evolved in a direct relationship to technological advancement.” It is 2016: advancements are endless, especially when it comes to horror films. Think of the famous 1897 horror film Dracula; the blood that looked like blobs of ketchup, the large amounts of makeup on the actors, it all seems so fake now. With advancements in technology producers are able to create horror films with undeniable visual effects. Better visual…

“A Novel Application of Microfluidic Assay to Evaluate the Role of Calponin in Platelet Function and Clot Formation” Introduction: Platelets are a very important aspect of blood clotting. They are also essential in the evolution of clots in Coronary and Cerebral arteries, which cause heart attacks and strokes, respectively. Every year, 610,000 people die of heart disease in the United States; this is 1 in every 4 deaths. Cardiovascular disease is the number one cause of death in the United…

also given for a period of time after certain surgeries. This is a drug that goes by the name Warfrin. It is an anitclotting medication, it keeps the blood thin and free of deadly blood clots so that it will flow smoothly through the circulatory system. In order for the blood to clot after a blood vessel is damaged a process needs to happen. The serine protease and the clotting factors II,VII,IX, and X are realeased from the liver and flow in the bloodstream throughout the body in an inactive…

Hemophilia Research Paper If you get a small papercut, it’s no big deal. Yes, it will hurt for a few minutes, but in a few days it’ll scab over, and be just fine. Unfortunately, it’s not the same case for everyone. There are many blood disorders, but one of the most common is hemophilia. Hemophilia affects over 200,000 people in the US each year. It causes the subject’s blood to not be able to clot properly, and leads to excessive bleeding (external and internal). The excessive…

leading to prolonged bleeding may be seen. In children with the mild disease symptoms may only surface at the time of a surgery of tooth extraction. Apart from the superficial bleeds , haemorrhage can also occur in the gastrointestinal system , genitourinary system, in the brain , which can impose a life threatening situation as well. Treatment of haemophilia- The definitive treatment is injecting the deficient factor VIII which immediately stops bleeding. Other symptomatic management is also…