Haemophilia B

Introduction Originating from the Greek words ‘haima’, meaning blood, and ‘philia’, meaning friend, hemophilia is a medical condition in which the individual lacks a certain clotting factor which prevents bleeding as a result of injury. In order of rarity from most to least, it features type A, B and C hemophilia and various severity levels. Type A hemophilia consists of 90% of cases, in which the individual lacks clotting factor VIII and 70% of patients have a severe level of hemophilia. Type B hemophilia is far less common, in which the person lacks clotting factor IX. (Crosta, P. 2013) Type C hemophilia is when the patient lacks clotting factor XI, can appear in both males and females, but is ten times less common than type A. Patients with a factor level of 0 to 1% are considered severe, in which they may have extensive spontaneous bleeding, including internal bleeding that the person may not even be aware of. Joints may bleed and blood may get into the muscles, which can cause lifelong damage. Severe hemophilia is unfortunately the most common variety. Ten percent of hemophiliacs are considered moderate (1 to 5%), in which they may suffer from spontaneous bleeding and will likely have prolonged bleeding.…

Children with hemophilia bleed for a longer time than others after an injury. Hemophilia commonly is of two types –A and B (uncommon is haemophilia C). There are various clotting factors in blood which are required for clotting of blood in the event of an injury. Deficiency of certain clotting factors can impair the clotting mechanism and increase the bleeding time. Hemophilia A is deficiency of clotting Factor VIII in blood. Hemophilia B is deficiency ofclotting factor IX in blood. Both…

chromosome. Hemophilia is a recessive disorder that’s sex-linked. The genetic defects to cause hemophilia occurs more often in men than in women. Hemophilia A, also known as VIII (FVIII) deficiency or classic hemophilia, a genetic disorder, that’s caused by a missing or defective factor VIII, a clotting protein. It’s passed down from parents to children, but about ⅓ of the cases are caused by a change in a gene, or a spontaneous mutation. Hemophilia occurs in about 1 in 5,000 live…

The two most common types of hemophilia are: Hemophilia A or Factor VIII (8) deficiency and Hemophilia B of Factor IX (9) deficiency. People with Hemophilia A are missing or have low levels of VIII blood clotting protein and people with Hemophilia B have low levels of IX clotting factor. Acquired hemophilia is rare and hereditary hemophilia, caused through mutations, is more common. Causes of F8 and F9 Gene Mutations There are two major types of hemophilia; type A and B. Hemophilia A is caused…

Hemophilia is a bleeding disorder that slows down the blood clotting process because of insufficient blood-clotting proteins. People who have hemophilia may bleed longer after an injury or they can experience spontaneous bleeding into the joints and muscle depending on the severity. There ae three types of hemophilia, Hemophilia A, B, and C. Hemophilia A and B are the most common types. In the past hemophilia affected life expectancy but currently with improved treatment, individuals with…

affected population frequency is low and the diagnosis of this disease is inherited about 70% of the time. Sometimes, hemophilia can occur when there is no family history of it and this is called sporadic hemophilia, having approximately 30% of people with non-inherited hemophilia, caused by a change in the person’s own genes (Blackwell 2012). According to Bolton-Maggs, there are different degrees of hemophilic disorders, having from lower risk cases to major and high risk diagnoses.…

Hemophilia is a genetic blood disease, which is symbolized by the importance of blood to clot, or compact even from inconsequential damage. Blood clotting and sudden gene mutation factor in the development of this disease. This disease is generated by an inadequacy of blood multifaceted called factors Therefore, with the nonappearance of factors, the blood clotting process is continued. There are two different types of Hemophilia, Hemophilia A and Hemophilia B. for example. Hemophilia A, the…

com) They are called first-pregnancy hemophiliacs if their first child is a boy, and he inherits the disease. Boys have one X chromosome, and one Y chromosome, but girls have 2 X chromosomes, and one Y chromosome. (worldbook.com) She won’t be a hemophiliac because the normal gene on her other X chromosome provides enough of the essential clotting factor. IN extremely rare cases, a girl can actually inherit the defective gene on both X chromosomes and will be a hemophiliac. In rare cases, a…

Hemophilia A and B is a bleeding disorders, congenital where the adults and children can have blood clot inherited condition. Children with hemophilia condition, have a bleeding problem and do not stop bleeding as quick as other children. For people who does not have hemophilia, a little, small cut its not a such big problem but, people who suffers from hemophilia, this little cut is deep bleeding inside their body. Especially it affects their knees, ankle, and elbows. In many occasion people…

Born in St. Joseph Memorial Hospital in Kokomo, Indiana, Ryan White was the little baby of Hubert and Wayne White. After being circumcised, the bleeding would not stop and after 3 days old, he was diagnosed with severe hemophilia A. He received a weekly infusion of Factor VIII (a blood product created from pooled plasma of non-hemophiliacs (Brannon, n.d.)), it is a common treatment for hemophiliacs at that time. He became extremely ill with pneumonia in December of 1984 even if he was healthy…