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49 Cards in this Set

  • Front
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VNS Therapeutic Range

Output current of 1.5-2.25 mA


Dosing range: 0-3.5mA

Initial Dose

0.25 mA

Common Pulse Width

250 to 500 microseconds

Dosing Parameters

Output current


Signal frequency


Pulse width


Signal on time


Signal off time

What is the goal of dosing?

Maximize therapeutic effect


Minimize side effects

Dosing: Phase 1

Ramp up Output current to 1.5-2.25 mA

Dosing Phase 2

Increase duty cycle


Every 3-6 months

Side effect managment

Adjust: pulse width,


output current,


and threshold for Autostim

Shortest off time for AutoStim

1.1minutes

Strategies to Manage Side Effects

1. Reduce pulse width 500-250


2. Reduce signal frequency 30 to 25 or 20


3. Reduce output current: Aspire 0.125


0.25 in others

AutoStim: Strategies to manage side effects

1Verify heartbeat detection auto stem: Adjust heartbeat sensitivity if necessary


reduce pulse width, reduce on time, reduce output current


Increase threshold for autostim current 10%

Impedance Range

Low less than 600 ohms


More than 5300 ohms

Exclusion zone for MRI

C7 to T8

MR conditional

VNS therapy MRI approval

Output current

Amount of elected current (mA) delivered during a single pulse of stimulation

Pulse Width

Duration of a single pulse (microseconds)

Signal Frequency

Number of pulses per second (Hz)

Dose Wave

VNS delivers a series of pulses (pulse train)

Ramp up/ramp down period

2 seconds for each

On time

Duration of time pulses are delivered

Off time

Interval between on-time


INCLUDES RAMP UP/ramp down

Lowest off time for AutoStim?

1.1 minutes


Can cause overstimulation with AutoStim enabled

Magnet mode: AutoStim

0.125 mA higher than AutoStim mode

Primary operating mode for VNS

Normal Mode

Typical duty cycle

30 seconds on


5 minutes off

Magnet Mode parameters

Output current mA


Pulse width usec


Magnet on time seconds

AutoStim side effect strategy

1. Verify heartbeat detection: adjust sensitivity


2. AutoStim: LOWER-1-pulse width, 2-ON time, 3-Output current


3. Raise AutoStim threshold 10%

Define normal mode stimulation

Most common used mode manages 25 hour on and off time.

Aspire SR: how long does magnet need to be applied?

6 seconds

How do we measure lead impedance?

Ohms

Signs of a short circuit?

Less than 600 ohms

What’s needed for generator diagnostics?

Test resistor kit.

Magnet above normal?

0.25

AutoStim above magnet

0.125

Tunneler: how much does it bend?

25 degrees

Before running diagnostics: tell the anesthesiologist:

Systole and bradycardia May happen

Implantable VNS components:

Lead


Generator

Why perform device diagnostics?

Test the integrity of the system


The lead and generator

Why perform device diagnostics?

Test the integrity of the system


The lead and generator

OR: high impedance

Lead fracture


Incomplete insertion


Electrode detachment from Bahia neeve

AutoStim enforced off time

Same as AutoStim on time

AutoStim enforced off time

Same as AutoStim on time

Length of blackout time?

30 seconds

How does AutoStim work?

Algorithm that measures heart rate increases relative to background heart based on a pre programmed threshold

Size of strain relief bend?

3 cm

What model is Demi pulse duo?

104

Minimum R-wave for heartbeat detection?

0.4mV

Patient kit

Two magnets


Two patient ID cards

Dual pen generators

102R


104