Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
7 Cards in this Set
- Front
- Back
|
Viroid
|
- Naked infectious RNAs that do not contain or encode any proteins
|
|
|
Parts of a virus
|
- Genome: RNA or DNA carrying genetic information
- Capsid: protein shell surrounding and protecting the genome - Envelope: a lipid bilayer surrounding and protecting the capsid in which surface glycoproteins are embedded. |
|
|
IRES
|
- internal ribosome entry site
- allows for translation initiation in the middle of mRNA - used by Poliovirus, HCV, ECMV |
|
|
Double-stranded RNA
|
- Produced by RNA viruses as a replication intermediate
- indicates viral infection when present - recognized by Type I interferon, Protein Kinase R, RNAseL. |
|
|
Viral Growth Curve
|
|
|
|
Viral replication patterns
|
- Lytic infection (e.g. Adenovirus)
- Persistent infection: an infection that lasts indefinitely - Chronic infection: A persistent infection in which viral replication is continuous (HCV, HBV) - Latent infection: A persistent infection in which viral production is not continually present (Herpesviurs). |
|
|
Nonenveloped DNA Virus replication mechanism
|
- enter by endocytosis
- uncoat in endosome/cytoplasm - genome transported to nucleus - viral transcription, DNA replication and assembly occur in nucleus - cells lyse to release particles |
