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36 Cards in this Set

  • Front
  • Back
a collection of genetic information directed towards self replication
the study of the effects of viral infection on the host
to spread through a population
genetic make-up
1. Expression of viral genes controlling the pathogencity
2. Physiological response to the infected individual to pathogenic determinants
3. Response of the population to the presence of the virus
a virus of reduced virulence that has accumulated so many mutations in pathogenic genes that it can not cause disease
avirulent/apathogenic strain
individuals who have never been exposed to any form of the virus leading to an immune response
immunologically naive individuals
the study of human infectious disease caused by viruses and other pathogens
epidemiology (humans)
epizoology (animals)
acquired immune deficiency syndrome
human immunodeficiency virus
one of a large group of viruses that affect bacteria
a treatment of a disease or condition designed to minimize discomfort
palliative treatment
severe acute respiratory syndrome
an inflammation of the brain or tissues of the upper CNS
a group of proteins (cytokines) secreted by virus-infected and certain other cells that act to induce a specific set of cellular antiviral and intitumor responses in other cells
interferons (IFN)
a DNA virus replicating in the ovaries of certain parasitic wasps that can suppress the immune response of the caterpillar prey to the developing wasp embryo
the common ancestral form or forms that precede the development of further diverging forms
(LUCA) Last Universal Common Ancestor
a poxvirus that normally infects South American hares
myxoma virus
the smallest/simplest pathogen able to control self-replication in a host cell; an infectious agent spread by ingestion that does not appear to contain any genetic material
virus particles that are normal in appearance but cannot initiate a productive replication cycle
defective virus particles
a virus in a mixed infection (usually in cultured cells) that provides a complementing function so that a co-infecting defective virus can replicate
helper virus
a plant pathogen that is the smallest known nucleic acid-based agent of infectious disease
an infectious agent spread by indigestion that does not appear to contain any genetic material; cellular proteins with an unusal folding manner
a slow, noninflammatory infection of the human CNS caused by a prion
Creutzfeldt-Jakob disease (CJD)
any infection that results in the production of more infectious virus at the end than at the start
productive infection
the actual number of infectious viruses produced in an infected cell; ranges from 10- 10,000
burst size
ability of certain bacteriophages to integrate its genome into that of the host bacteria and remain associated as a genetic passenger as the bacteria replicate
the alteration of a cell by inseertion of one or more foreign or mutant genes
herpes simplex virus
a set of endonuclease-mediated responses to foreign DNA sequences encoded by bacterial genes designed to destroy the genomes of invading bacteriophages and plasmids
bacterial restriction
without detectable symptoms
the time between initial infection and the onset of notable symptoms of disease
incubation period
the source of an infectious agent
the agent or means by which an infectious agent is spread from one individual to another