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67 Cards in this Set

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Cell structures virus don't have

Cytoplasm, mitochondria, ribosomes

CMR

All virus are haploid except

Retro virus

Virus that have segmented DNA

Inflienza and rota virus

Virus are killed in which temp

50/60°C

All RNA virus consists of single stranded RNA except

Reo virus (rota virus) which have double stranded RNA

Virus:- Ab & interferon sensitive or resistant?

Resistant

Virus DNA integreted in which part of host cell?

Chromosome

DNA সেলের কোথায় থাকে?

Appearence of virus under electron microscope

Spherical/Rods

Virus is composed of

Internal core DNA/RNA (not both) covered by a protective protein coat --> capsomere -> Antigenic

Structure

Viral enveloped is composed of

Lipoprotein

Lipid of virus envelop comes from

Host cell membrane

Lipid of virus envelop comes from host cell membrane except in,


( theb from where)

Herpes virilus from nuclear membrane

Viral envelope comes from which part of host cell?

Cytoplasmic membrane

Which virus get envelope other site than cytoplasmic membrane and which site?

HSV from nuclear membrane

Super Ag producing viruses are

CMV, Retro viru, EBV, Mouse mammary tumor virus,

CREM

What is defective virus and give an ex?

Virus having nucleic acid and protein but can't replicate without a helper virus.

What is pseudovirion and what is their special feature?

Virus that contain host cell DNA during replication instead of viral DNA.


Can infect cell but don't repicate.

What is prion?

Infectious particle composed of solely protein molecule, no nucleic acid.

Nature of diseases produced by prions-

Slow Disease / transmissable spongiform encephalopathy.

Slow viral diseases produced by prions

1.Kuru


2.Gerstmann Straussler Scheinker syndrome


3.Fatal familial insomnia


4.Variant creuztzfeldt-Jackob Disease


5.Creutzfeldt-Jackob disease

KGF Valo Cinema

Slow viral dzs produced by virus-

1.SSPE by Measles


2.Progressive multifocal leukoencephalopathy by HIV & HPV


3.AIDS by HIV

SPA

DNA Viruses replicate in nucleus except

Pox virus (Cytoplasm)

RNA virus replicate in cytoplasm except

Reatro virus, influenza virus, hepatitis delta virus

DHIR

What is lysogeny?

Process by which viral dNA become integrated into host cell dNA, replication stops, and no progeny virus is made.

Lysogenic bacteria:

1.Coryn. Dip - diptheria toxin


2. Staph aureus- Entero toxin


3. Strep. Pyoge- erythrogenic toxin


4. V. Cholare- Choleragen


5. Cl. Tetany - tetanospasmin


6. Cl. Botulinum - botulinum toxin

Can virus be cultured?

No. (Cell culture isn't a regular culture)

PCR Based tests are

1.Viral ag detectn in bld & body fluid


2.viral nucleic acid detectn in blood and body fluid

In eclipse phage virus can't infect - T/F

T - bcz genome is separated

Virus czing latent infectn.

HSV-I, HSV-II


VZV


EBV


CMV

Oncogenic viruses

HPV-(1,2,4,7,6,16)


HHS-8


HBV


HCV


EBV


HTCLV

Oncogeniv bacteria-

H. Pylori - Gastric ca


Cl. Jejuni - MALToma

Oncogenic parasite-

Schistosoma haematobium


Clorchis sinensis


Opisthorchis sinensis

Cong. Infectn that czs fetal loss

HEV,


Measles,


Brucellosis,


Malaria

Non-enveloped dNA viruses

Parvo virus B19


Papilloma/Polioma virus


Adeno virus

Enveloped DNA viruses

Herpes virus family


Pox virus family


Hepadna (HBV) virus

Neoplasm caused by Epstein Bar Virus -

1. Burkitt's lymphoma


2. Nasopharyngeal cancer


3. B-cell lymphoma in immuno sup. pt specially in AIDS pt


4. Hodgkin lymphoma


5. Oral hairy leukoplakia (AIDS pt)


6. Primary CNS lymphoma

HOLy BNB

Neoplasm caused by HPV

1. Genital warts


2. Condyloma acunimatum of genitalia / Buschke-Lowenstein Tumor


3. Ca cervix, vulva, penis, anus


4. Resp tract papilloma


Vaccine preventable cancer

1. Ca cervix by HPV


2. HCC by HBV

Carcinoma caused by Herpis simplex virus -

Kaposi's sarcoma by HHS-8

Most common cause of genital ulcer

Genital herpis by HSV-2

Which members of Herpes family causes recurrent infection?

HSV-1 & HSV-2 bcz they give incomplete immunity after clinical infection.

Which members of Herpes family forms giant cell / give CMI?

First 4 members


HSV-1


HSV-2


VZV


CMV

Who is 'Kissing virus'?

HSV-1


EBV

What type of rash pruduced by Herpes family? (HSV-1,HSV-2 & VZV)

Vesicular rash

Virus causing aseptic meningitis

Polio


Echo


HSV-2

Common cause of viral meningitis

Mumps


Coxsakie virus


Echo virus

Sexually transmitted viral diseases

HIV


HPV


HAV,HBV,HCV


CMV


Genital warts (by HPV 1,2,4,7)


Genital herpes by HSV-2

Primary, recurrent & latent disease by VZV -

Chicken pox (varicella), Shingles & Zoster

Neurotropic viruses are-

1.Rabies


2.Polio


3.HSV


4.VZV


5.Measles


6.HTCLV


7.HIV

What is Reye's syndrome?

When a VZV or Influenza-B infected child is treated with aspirin, it produces some cx together they callwd Reye's syndrome.

Features of Reye's syndrome -

Encephalopathy


Liver damage


Life threatening cx

Viruses that have transplacental transmission -

HIV


HBV


Parvo virus B-19


CMV


Rubella

Giant cells found in / Viruses that give CMI -

-Herpes এর প্রথম চারটা (HSV-1, HSV-2, VZV, CMV)


-HIV


-RSV


-Measles

Between CMV & EBV, which one is Heterophil Ab positive and which one is negative?

CMV - Neg-


EBV - Pos+

Infectious mononucleosis caused by

HIV-1


Toxoplasma


EBV


CMV


HHV-6,7

Hi TECH

Natural host of CMV virus & where it latents

Human is the natural host


Latent in leukocytes

CMV is transmitted by

Transplcenta,


Birth canal


Breast milk


Urine


Saliva


Sexual


BT


Organ transplantation

Roseola infentum is caused by

HHV-6,7

Clinical features of CMV infection

Brain


1.Cong. anomalies > Microcephaly> Seizure > Mental retardation


2.Deafness



Abdome


1. Hepatospleenomegaly


2. Jaundice



Blood


1. Purpura


2. Blood dyscrasia

Disease produced by EBV

1. IM / Glandular fever


2. Burkitt's lymphoma


3. B-cell lymphoma


4. Nasopharyngeal Ca


5. Oral hairy leukoplakia


6. Thymic Ca


7. X-linked leukoproliferative syndrome

Common cx of EBV / IM

•Severe pharyngeal edema


•Antibiotic-induced rsh


•Hepatitis


•Prolonged post viral fatigue


•Jaundice

Neurological Cx of EBV/IM

• Cranial Nervr palsies


• Polyneuritis


• Transverse myelitis


• Meningoencephalitis

Cardiac cx of EBV / IM

•Myocarditis


•Pericrditis


•ECG abnormalities

Haematological & renal cx of EBV / IM

• Haemolytic anaemia


• Thrombocytopenia


&


• Glomerulonephritis


• Interstitia Nephritis

Largest and most complex vieus

Pox virus

Smallest virus

Polio

Pox virus family consists of

1. Small pox


2. Vaccinia


3. Molluscum contagiosum virus