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77 Cards in this Set
- Front
- Back
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Transcription of iridoviruses differs from that of asfarviruses in that iridoviruses:
a. Produce nested transcripts b. Use cellular RNA polymerase c. Use viral DNA polymerase d. Produce polycistronic messages e. Carry their RNA polymerase int othe cell as part of the virion |
b. Use cellular RNA polymerase
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Picornaviruses differ from caliciviruses in that picornaviruses utilize which of the following replication strategies
a. Produce nested transcripts of mRNA b. Carry the viral RNA polymerase into the cell c. Utilize an internal ribosomal entry site in mRNA for translation d. Produce subgenomic mRNA e. Produce one mRNA for each protein |
c. Utilize an internal ribosomal entry site in mRNA for translation
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Alphaherpesvirinae members
a. Replicate slowly in epithelial cells b. Achieve latency in secretory glands c. Are lymphotropic d. Achieve latency in neural ganglia e. Are not cytolytic |
d. Achieve latency in neural ganglia
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Which of the following virus families contain nonenveloped virions?
a. Herpesviridae b. Poxviridae c. Caliciviridae d. Togaviridae e. Flaviviridae |
c. Caliciviridae
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The tegument is a structural component of _______ and contains a viral protein used for ________.
a. Poxviruses; transcription b. Iridoviruses; DNA replication c. Herpesviruses; splicing mRNA d. Herpesviruses; host mRNA degredation e. Poxviruses; transcription activation |
d. Herpesviruses; host mRNA degredation
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During latency of herpesviruses, the viral genome:
a. Integrates inot the cellular DNA b. Is degraded c. Remains episomal in the nucleus d. Is not transcribed e. Continues to replicate |
c. Remains episomal in the nucleus
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The genera of the Picornaviridae differ in which of the following properties?
a. Capsid size b. Number of capsomers c. Number of proteins composing the capsomers d. Number of open reading frames in the genome e. Acid stability |
e. Acid stability
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The major organ or system targeted by feline calicivirus is which of the following?
a. Gastrointestinal tract b. Respiratory system c. Reticuloendothelial system d. Liver e. Central nervous system |
b. Respiratory system
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The reservoir of malignant catarrhal fever virus in countries outside of Africa is:
a. Birds b. Mosquitos c. White-tailed deer d. Sheep e. Ticks |
d. Sheep
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Pseudorabies virus may cause disease in all of the following EXCEPT:
a. Monkeys b. Rodents c. Swine d. Cats e. Goats |
a. Monkeys
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Infectious bronchitis virus (IBV) of poultry, in addition to respiratory disease, also causes:
a. Epidemic tremors b. Hepatic failure c. Decreased egg production d. Feather loss e. Diarrhea |
c. Decreased egg production
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The Poxviridae members carry all of the following as viral structural proteins EXCEPT:
a. Lateral body b. RNA polymerase (transcriptase) c. mRNA capping enzyme d. mRNA splicing enzyme e. mRNA poly A polymerase |
d. mRNA splicing enzyme
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Which of the following viruses us a viral protease to cleave and inactivate the cellular cap-binding complex leading ot uncapped cellular mRNA?
a. Bovine herpesvirus-1 b. Poliovirus c. Vesicular exanthema virus d. West Nile virus e. Feline coronavirus |
b. Poliovirus
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Which of the following virus families contains a member associated with lymphoid tumors in poultry?
a. Herpesviridae b. Poxviridae c. Caliciviridae d. Togaviridae e. Flaviviridae |
a. Herpesviridae
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A vaccine for foot and mouth disease:
a. Is widely used in the US and Europe b. Prevents infection and shedding of virus c. Is serotype-specific d. Is acid-stable e. May cause significant lesions and drop in productivity |
c. Is serotype specific
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Which of the following viral genera contains members associated with respiratory disease and abortion in dogs, horses, and cattle?
a. Suipoxvirus b. Ranavirus c. Enterovirus d. Alphaherpesvirus e. Vesivirus |
d. Alphaherpesvirus
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Which of the following viral genera contains members associated with die-offs of frogs?
a. Suipoxvirus b. Ranavirus c. Enterovirus d. Alphaherpesvirus e. Vesivirus |
b. Ranavirus
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Which of the following viral families contains the larges virus of animals?
a. Herpesviridae b. Poxviridae c. Caliciviridae d. Togaviridae e. Flavivirdae |
b. Poxviridae
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The viruses used to control rabbit populations in Australia are classified in which of the following families?
a. Coronaviridae and Herpesviridae b. Caliciviridae and Picornaviridae c. Poxviridae and Caliciviridae d. Togaviridae and Flaviviridae e. Picornaviridae and Coronaviridae |
c. Poxviridae and Caliciviridae
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Which of the following is NOT a reportable/ notifiable disease?
a. Pseudorabies b. Foot and mouth disease c. Swine vesicular disease d. Vesicular exanthema of swine e. Avian encephalomyelitis |
e. Avian encephalomyelitis
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Smallpox was able to be eradicated via mass vaccination of people against the viral agent. Which of the following viral properties was a major contributor to this capability?
a. It causes persistnet infection of the host b. It has no animal reservoir c. It induces short-lived humoral response d. It is unstable in the environment e. Infection may be reactivated by stress |
b. It has no animal reservoir
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Which of the following poxviruses is NOT routinely transmitted by insects?
a. Parapoxvirus b. Goatpoxvirus c. Swinepoxvirus d. Sheeppoxvirus e. Fowlpoxvirus |
a. Parapoxvirus
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Foot and mouth disease virus is of great concern economically for many reasons including:
a. It is highly contagious b. It has high mortality c. It affects horses, cattle, swine, and goats d. Its transmissibility via mosquitoes e. Its ability to cause latent infections that re-emerge later in life |
a. It is highly contagious
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Orf, the disease caused by parapoxvirus is most significant in lambs because:
a. It causes oral lesions that hinder nursing b. It spreads systemically c. There is no vaccine d. It is transmitted by insects e. It causes cutaneous fibromas that enlarge and spread |
a. It causes oral lesions that hinder nursing
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Alpha herpesviruses usually develop latency in:
a. Sensory ganglia b. Dermal basal cells c. Secretory epithelium d. Lymphocytes e. Reticulo-endothelial system |
a. Sensory ganglia
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The herpesvirus capsid is:
a. helical b. icosahedral c. pleiomorphic d. octahedral e. decahedral |
b. icosahedral
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The herpesvirus virion host shutoff protein involved in herpesvirus replication is released from the virion at/in the:
a. cell membrane b. cytoplasm c. nuclear pore d. nucleus e. endoplasmic reticulum |
b. cytoplasm
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Alpha trans-inducing factor protein encoded by herpesviruses is associated with the:
a. nucelocapsid b. envelope c. genome d. tegument e. capsomere |
d. tegument
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Herpesvirus virion structural proteins are encoded by:
a. capsid genes b. alpha genes c. beta genes d. gamma genes e. delta genes |
d. gamma genes
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Herpesvirus recrudescence may be induced by
a. a variety of stressors b. Latency Associated Transcript c. re-exposure to the same virus d. exposure to a closely related virus e. alpha trans-inducing protein |
a. a variety of stressors
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During its replication cycle, herpesvirus DNa is replicated by a product(s) of:
a. cellular gene(s) b. alpha gene(s) c. beta gene(s) d. gamma gene(s) e. delta gene(s) |
c. beta gene(s)
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Herpesviridae:
Viral messenger RNA is transcribed from viral DNA by a transcriptase which is a(n): a. cellular gene product b. alpha gene product c. beta gene product d. gamma gene product e. cellular onc gene product |
a. cellular gene product
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Bovine herpesvirus 1 often targets the:
a. lung b. liver c. brain d. upper respiratory tract e. intestine |
d. upper respiratory tract
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The normal host of the herpesvirus causing Malignant Catarrhal Fever in cattle often is
a. gazelle b. buffalo c. zebra d. wildebeest e. bison |
d. wildebeest
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The "natural" host of pseudorabies virus is:
a. dogs b. cattle c. sheep d. swine e. wildebeest |
d. swine
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Equine herpesvirus 3 usually causes:
a. vaginitis b. rhinopneumonitis c. abortion d. encephalitis e. T lymphocyte proliferation |
a. vaginitis
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A common consequence of equine herpesvirus 1 infection in horses is:
a. Vaginitis b. Abortion c. Enteritis d. Pneumonia e. B lymphocyte proliferation |
b. Abortion
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Canine herpesvirus infection may cause a generalized infection in pups because of:
a. hypothermia in pups b. stress of weaning c. viral mammilitis in bitch d. failure to acquire passive immunity e. close contact |
a. hypothermia in pups
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Infectious Mareks disease virus is produced in:
a. T lymphocytes b. B lymphocytes c. feather follicle epithelium d. pharyngeal mucosa e. bursa |
c. feather follicle epithelium
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Psittacine herpesvirus (Pacheco's disease) often results in necrotic lesions in the:
a. liver b. upper respiratory tract c. intestinal epithelium d. lymphoid tissues e. brain |
a. liver
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Marek's disease virus infection in chickens results in a proliferation of:
a. T lymphocytes b. B lymphocytes c. nerve cells d. epithelial cells e. endothelial cells |
a. T lymphocytes
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Gamma herpesvirus infections often target:
a. nerve cells b. secretory glands c. mucosal epithelium d. lymphocytes e. macrophages |
d. lymphocytes
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In herpesvirus infected cells, virion capsids assemble in/at the:
a. nucleus b. cytoplasm c. inner lamella of the nuclear membrane d. plasma membrane e. Golgi |
a. nucleus
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The antiviral effect of nucleoside analogues is due to their interaction with the following viral enzyme:
a. virion host shutoff protein b. alpha trans inducing factor c. Latency Associated Transcript d. thymidine kinase e. packaging protease |
d. thymidine kinase
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The viruses that utilize terminal hairpins to prime DNA replication are which of the following?
a. Parvoviridae b. Circoviridae c. Polyomaviridae d. Papillomaviridae e. Adenoviridae |
a. Parvoviridae
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The viruses that utilize a terminal protein to prime DNA replication are which of the following?
a. Parvoviridae b. Circoviridae c. Polyomaviridae d. Papillomaviridae e. Adenoviridae |
e. Adenoviridae
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The viruses that have a circular genome of double-stranded DNA are which of the following?
a. Parvoviridae b. Circoviridae c. Polyomaviridae d. Papillomaviridae e. Adenoviridae |
c. Polyomaviridae
d. Papillomaviridae |
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The first step of replication following uncoating of picornaviruses is which of the following?
a. Transcription b. Translation c. Genomic replication d. Budding e. Assembly |
b. Translation
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Abortive Replication of a virus may lead to which of the following?
a. Cell lysis b. Virus release c. Cytopathic effects d. Cellular transformation e. Complementation |
d. Cellular transformation
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The genomic replication of picornaviruses is promed by which of the following structures?
a. Terminal protein b. Penton c. Genomic hairpins d. Internal ribosomal entry site e. Inverted terminal repeats |
a. Terminal protein?
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The virus family that contains many pathogens of fish is which of the following?
a. Adenoviridae b.Circoviridae c. Poxviridae d. Iridoviridae e. Picornaviridae |
d. Iridoviridae
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The original source of the virus causing Vesicular Exanthema in swine is which of the following?
a. Birds b. Mosquitoes c. Ticks d. Feral swine e. Marine mammals |
e. Marine mammals
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The species of animal that may serve as an amplifier in an outbreak of Foot and Mouth Disease Virus, producing high levels of virus in respiratory secretions is which of the following?
a. Swine b. Sheep c. Goats d. Cattle e. Deer |
a. Swine
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Which of the following viruses require the cellular nucleus for replication?
a. Poxviruses b. Picornaviruses c. Caliciviruses d. Asfarviruses e. Iridoviruses |
e. Iridoviruses
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The virus family that contains many pathogens of fish is which of the following?
a. Adenoviridae b. Circoviridae c. Poxviridae d. Iridoviridae e. Picornaviridae |
d. Iridoviridae
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Which of the following diseases is currently endemic in the US?
a. African Swine Fever b. Foot and Mouth Disease c. Scrapie d. Lumpy Skin Disease e. Sheep Pox |
c. Scrapie
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The viruses of Cowpox, Monkey Pox, and Encephalomyocarditis (Picornavirus) share a common characteristic in that the natural host for all is which of the following?
a. Ticks b. Cattle c. Carnivores d. Rodents e. Humans |
d. Rodents
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Which of the following is notifiable because of the disease resemblance to foot and mouth disease?
a. Vesicular exanthema b. Winter dysentery c. Viral arteritis d. Rubivirus e. Sialodacryadenitis |
a. Vesicular exanthema
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Whihc of the following descriptions applies to the Caliciviruses?
a. Small nonenveloped virus b. Linear genome of negative polarity c. Segmented genome d. Pleomorphic enveloped virus e. Large helical capsid |
a. Small nonenveloped virus
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From what Latin word is the family name Caliciviridae derived and why (what does it describe)?
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Calyx
it describes its cup-like strx |
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Orf is a disease that is most significant in which of the following hosts?
a. Kittens b. Lambs c. Wildlife d. Cattle e. Foals |
b. Lambs
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All of the following poxviruses are transmitted by arthropods EXCEPT:
a. Avipoxvirus b. Lumpy skin disease virus e. Sheep- and goatpox viruses d. Suipox virus e. Smallpox virus |
e. Smallpox virus
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Feline Calicivirus may affect all of the following tissues EXCEPT:
a. Upper repiratory tract b. Conjunctiva c. Lungs d. Central nervous system e. Joints |
d. Central nervous system
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The primary or main target cell of malignant catarrhal fever virus is which of the following cells?
a. Lymphocytes b. Red blood cells c. Neurons d. Neutrophils e. Osteoclasts |
a. Lymphocytes
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All of the following herpesviruses may lead to abortion in pregnant animals EXCEPT:
a. Equine herpesvirus-1 b. Bovine herpesvirus-1 c. Canine herpesvirus d. Pseudorabies virus (in swine) e. Marek's disease virus |
e. Marek's disease virus
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Which of the following herpesviruses may be associated with neoplasia?
a. Equine herpesvirus-1 b. Bovine herpesvirus-1 c. Canine herpesvirus d. Pseudorabies virus (in swine) e. Marek's disease virus |
e. Marek's disease virus
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Poliovirus, avian encephalomyelitis virus, and Teschen disease virus gain acces to the central nervous system after dissemination from which of the following sites?
a. Respiratory tract b. Gastrointestinal tract c. Direct inoculation into the bloodstream d. Insect vector bite e. Reproductive tract |
b. Gastrointestinal tract
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Which of the following statements about Foot and Mouth Disease or its agent is TRUE?
a. Infection invariably leads to death b. Infections are localized with no systemic spread c. Recovered animal are immune to all serotypes d. Lesions in sheep and goats are the most severe while infection in cattle is often subclinical e. A carrier state may exist in recovered cattle with prolonged shedding |
e. A carrier state may often exist in recovered cattle with prolonged shedding
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The viruses of Duck Plague, Pacheco's Disease, and Infectious Laryngotracheitis are all members of which of the following family?
a. Iridoviridae b. Herpesviridae c. Picornaviridae d. Coronoaviridae e. Arteriviridae |
b. Herpesviridae
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Infectious bronchitis of chickens may also lead to which of the following disease manifestations?
a. Paralysis b. Reduced egg production and abnormal eggs c. Neoplasia d. Atrophy of bursa of Fabriscus e. Anemia |
b. Reduced egg production and abnormal eggs
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Viruses withing this vamily may contain one or two lipid membranes around the core (both forms are infectious) and some mebers are associated with fibromas in certain species such as rabbits.
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Poxviridae
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Members of this family are nonenveloped with 32 cup-shaped capsomers, and one member casues a lethal disease of European rabbits and has been used for rabbit population control in certain geographic regions
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Caliciviridae
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Some memvers of this family have been associated with hepatitis in ducks and turkes, as well as infectious hepatitis of humans, while others within this family have been linked to encephalomyocarditis in elephants (transmitted from rodents)
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Picornaviridae
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For which of the following families are specific antiviral medications available to treat infections?
a. Iridoviridae b. Herpesviridae c. Picornaviridae d. Coronaviridae e. Arteriviridae |
b. Herpesviridae
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The different genera within this family are classified based on acid (pH) stability, and for translation of mRNA, an internal ribosomal entry site is used.
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Picornaviridae
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Members of this family replicate at least partially in the nucleus, have complex morphology, and many members are important pathogens of fish and frogs
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Iridoviridae
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Members of this family have a genome with covalently closed ends (terminal hairpin loops) and inverted repeat sequences, and members within a genus share antigenicity such that immunization with one protects against others within the genus
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Poxviridae
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