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6 Cards in this Set

  • Front
  • Back
1st generation antipsychotics
phenothiazines
thioxanthenes
butyrophenones
Antagonists block action of D2 receptors for dopamine:
-reduce s/s of schizophrenia (delusions/hallucinations
-also antagonistic to ACH, NE, histamine=dry mouth EPS (haldol)
pharmacokinetics
How the body affects the drug i.e. how is the drug metabolized by the liver?
pharmacodynamics
The changes that a drug produces in a person.
therapeutic index
the ratio of the lethal dose to the effective dose indicating the safety of the drug.
Acetylcholine
neruotransmitter released by the post ganglionic neurons of the parasympathetic nervous system
Clozapine
atypical antipsychotic drug: potential suppression of bone marrow-reg WBC weekly. SE:sedation, hypersalivation,tachycardia, dizzyness.