Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/5

Click to flip

5 Cards in this Set

  • Front
  • Back
Draw Glycolysis and GNG
Glycolysis aside GNG
Malonate is a competitive inhibitor of succinate in the succinate dehydrogenase reaction. Why can this be overcome by raising the oxaloacetate concentration.
Assuming a sufficient supply of acetyl-CoA raiseing the oxaloacetate concentration has the effect of raiseing all the Citric Acid Cycle intermediates including succinate. Since malonate is a competitive inhibitor this can be overcome by increasing succinate
Which of the following metabolites undergoes a net oxidation a-ketoglutarate, succinate, citrate, acetyl-CoA?
Only acetyl-CoA under goes a net oxidation all the others are regenerated in one turn of the CAC.
Why is the oxidation of succinate to fumarate only associated with the production of two (2) ATPs, while oxidation of malate to oxaloacetate produces three (3) ATP?
The oxidation of succinate to fumarate catalyzed by succinate dehydrogenase involves the reduction of FAD to FADH2. Electrons from FADH2 enter the Electron Transport Chain at CoQ missing Complex I which pumps H+ as a result. Malate to Oxaloacetate catalyzed by malate dehydrogenase involves the reduction of NAD+ to NADH. The NADH electrons enter the ETC at complex I and therefore store more energy to make ATP by pumping H+.
Why are people on a high protein diet instructed to drink lots of water?
The nitrogen in from a high protein diet must be disposed of as urea. Since urea is excreted in relatively dilute amounts the diet must be accommpanied by sufficient water intake.