The Cori Cycle has many parts to it ultimately leading to the breakdown of glucose and the diffusion of lactate with the liver. In the Cori cycle there is the conversion of glucose to lactate through anaerobic glycolysis in muscle cells, the diffusion of lactate from muscle cells into the bloodstream then being transported to the liver. To the conversion of lactate to glucose through gluconeogenesis. Ultimately back to the diffusion of glucose back into the bloodstream going to the muscle cells, thereby finishing the cycle.
The cycle is located in the skeletal muscle, extra hepatic tissues and liver. So basically the Cori cycle is a link for gluconeogenesis with anaerobic glycolysis, using different tissues to compartmentalize opposing metabolic pathways.
Uridine diphosphate (UDP) glucose is a nucleotide sugar used in many pathways. It is the precursor for glycogen and sucrose. It can also be used as enzymes to breakdown reactions. These enzymes are called UDP glucose pyrophosphorylase and UDP glucose dehydrogenase. The pathway that …show more content…
Glycogenolysis occurs in the muscle cells and liver tissues in response to hormonal and neural signals. It is very important in the fight-or-flight response of the body. Glycogenolysis regulates hormonally blood sugar levels through glucagon and insulin. Epinephrine regulates glycogenolysis in the fight-or-flight response.
Epinephrine can causes a rapid increase in blood glucose concentration. A majorly common disease having to do with epinephrine and blood glucose levels is hyperglycemia. Hyperglycemia is abnormal high blood glucose/sugar levels. Increased epinephrine induced hyperglycemia has elevated levels of glucagon and cortisol in the body. This increased levels can lead to glucose intolerance and can inhibit future glucose