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17 Cards in this Set

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  • Back
What does peroxidase do in the thyroid?
aids in the iodination of tyrosine residues on thyroglobulin to synthesize thyroid hormone
What is Hashimoto’s disease?
autoimmune hypothyroidism
What is Grave’s disease?
autoimmune hyperthyroidism
What is the main drug used to treat hypothyroidism?
Levothyroxine
Which would have a faster onset of action, levothyroxine or liothyronine?
liothyronine
Which causes a goiter, iodine deficiency or hyperthyroidism?
Both
What is the main side effect of thiocyanate?
aplastic anemia
What is the mechanism of action of 131I in treating hyperthyroidism?
radioactive destruction of some thyroid tissue.
What is the biggest side effect of 131I?
hypothyrodism
Potassium iodide would be used to treat hashimotos’s disease or grave’s disease
Grave’s disease
What is the main mechanism of action of iodide salts in treating hyperthyroidism?
high levels inhibit the secretion of thyroid hormone
What would you use to control a case of hyperthyroidism before a surgical removal of part of the thyroid gland?radioactive iodide, high concentrated iodide salts, methimazole
high concentrated iodide salts, methimazole
What agent would work rapidly to control a thyroid storm?
high concentrated iodide salts
What is the mechanism of action of propylthiouracil in treating hyperthyroidism?
blocks the peroxidase catalyzed reactions to inhibit thyroid hormone synthesis
Which has a faster onset of action, Lugol’s solution or methimazole?
Lugol’s solution
What are some of the side affects of propylthiouracil?
Pruritic rash, arthralgias, hypoprothrombinemia, agranulocytosis
Which agent would you most likely use to treat hyperthyroidism during pregnancy?
propylthiouracil