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44 Cards in this Set
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dosage chlorpromazine (thorazine) for intractable hiccups? |
Initial oral dose is 25 mg three times daily for up to seven to ten days. The dose can be titrated up to 50 mg four times daily for improved control. Intravenous administration may be more effective, although the drug must be infused in 500 to 1000 mL saline with the patient in the supine position to prevent hypotension. |
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Dosage: metoclopramide for intractable hiccups |
10 mg three or four times daily for up to 7 to 10 days |
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Side effect of metoclopramide |
tardive dyskinesia |
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Side effects of chlorpromazine |
Potential side effects with short-term usage include dystonic reactions and drowsiness. Long-term therapy increases the risk of tardive dyskinesia. Chlorpromazine is contraindicated in elderly patients with dementia. |
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physical maneuvers to stop hiccup |
interrupting normal respiratory function (eg, breath holding, Valsalva maneuver) or nasopharyngeal/uvula stimulation (eg, sipping cold water, gargling with water) |
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a disorder of diminished motivation |
abulia |
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components of the CAM ICU |
acute onset or fluctuating course; inattention; disorganized thinking; altered LOC |
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requirements to diagnose delirium using CAM ICU method |
1+2 and either 3 or 4 |
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4 questions for disorganized thinking |
will a stone float on water; are there fish in the sea; does 1 pound weigh more than 2 pounds; can you use a hammer to pound a nail? |
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slow regular breathing: diagnosis |
drugs or hypothyroidism |
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components of brainstem testing in comatose |
pupil size, pupillary light reflex, corneal, Doll's eye reflex; cough and gag; cold calorics |
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reason for sneaking from the side to test corneal reflex |
If the patient blinks because they see you, you have tested CN II and VII. If they blink because they hear you, you have tested CN VIII (Acoustic) and VII. |
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cranial nerves involved in oculocephalic or Doll's eye reflex |
CN VIII communicates to both CN III and VI in the pons to produce horizontal eye movement |
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Fever by IDSA criteria |
38.3 or 101 |
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7 important non infectious causes of fever in the icu |
Drug fever, pancreatitis, acalculous cholecystitis, thyroid storm, adrenal insufficiency, transfusion reaction, post op fever (plus dvt) |
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Important causes of fever in the icu |
IV Cath related infection, surgical site infection, cholangitis, endocarditis, c diff, si.usitis, pna, uti |
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When to treat fever with empiric antibiotics |
Clinical condition deteriorating or in shock or neutropenic, with VAD, nee fever >102 |
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Causes of post-op fever: pathophysio
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due to tissue trauma with cytokine release, circulating bacterial endotoxins from endogenous gut flora
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4 predominant infectious causes of postoperative fever
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Surgical site infection, pneumonia, urinary tract infection, and intravascular catheter infection
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most common noninfectious cause of postoperative fever
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medication reaction; antimicrobial agents or heparin are the drugs most frequently implicated; other causes include pancreatitis, DVT, transfusion, gout
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management of post-op fever
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remove all unnecessary treatments (meds, NGT, IV cath, Foley)Acetaminophen no routine / empiric antibiotics unless hemodynamically unstable - and d/c after 2d if no source identified
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criteria to safelyobserve patients without giving Abx in post-op neurosurg fever
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<39.4ºC (102.9ºF)CSF WBC <7,500/µLCSF glucose >10 mg/dLdelirium, seizure, or surgical site inflammation
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verapamil dose for rate control in Afib |
240 to 480 mg daily in 3 to 4 divided doses; extended release: Usual maintenance dose range: 180 to 480 mg once daily |
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verapamil dose for PSVT prophylaxis |
Immediate release: 240 to 480 mg daily in 3 to 4 divided doses |
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TCD mean velocity accepted as representing prob significant degree of arterial narrowing |
100-120 cm/s mean velocity |
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increase in TCD implies |
hyperaemia or vasospasm |
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what is the Lindegaard ratio? |
ratio between mean velocity in MCA and mean velocity in cervical ICA, if 3 or more then the high intracranial velocity likely to be due to vasospasm |
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Labs to request for ISTH DIC scoring? |
Platelets, D-dimer, PT, Fibrinogen |
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common causes of thrombocytopenia in the hospitalized patient |
drugs, HIT, liver disease, multi-organ failure, DIC sepsis`
Less common: TTPHUS, lymphoma, leukemia, APAS, PNH, nutrient deficiency (B12, folate, copper) |
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asymptoamtic patient with thrombocytopenia, differentials? |
immune thrombocytopenia (ITP), occult liver disease, HIV infection, myelodysplastic syndromes |
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drugs commonly associated with thrombocytopenia |
heparin beta lactam Abx, vancomycin, piperacillin, sulfonamides, bactrim, linezolid, levofloxacin?phenytoin, VPA, CMZ, haldol? ibuprofen?, naproxen?, acetaminophen? simvastatin?, furosemide? ranitidine? |
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What is the ABCDE bundle? |
Awakening and Breathing trials (AB) their coordination (C), choosing the right sedative when indicated (C), delirium monitoring and management (D) and early mobility (E) |
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the big 5 trials of interventional management of stroke in 2015 |
better results compared to IV tPA alone with intracranial ICA or MCA occlusions up to 6 hours of onset MR CLEAN SWIFT PRIME EXTEND IA ESCAP and REVASCAT |
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esmolol for Afib in RVR - how to dose |
load 0.5mg/kg x 1 min then 50 ug/kg/min x 4 mins; ual effective dose 50-200 ug/kg/min; 25 might be adequate |
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diltiazem for Afib in RVR - how to dose |
0.25 mg/kg actual body weight over 2 minutes (average adult dose: 20 mg); ACLS guideline recommends 15-20 mg |
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DDx for sinus tach |
4 big differentials: PE MI Sepsis Dehydration
Always treat: PainFeverAnxiety anemia Zebras: Hyperthyroidism Malignant hyperthermia |
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max value of CHADS/ CHADSVASC? |
6 and 9 |
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CHADS2 score components |
prior strokeand transient ischemic attack, congestive heart failure anddysfunction, hypertension, age of 75 years or older, and diabetesmellitus (score range, 0-6) |
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CHADSVASC score components |
increases the point value from 1 to 2 for age of 75 years andolder and adds elements for female sex, vascular disease,and age of 65 through 74 years (score range, 0-9) |
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when is OAC recommended for stroke prevention in CHADS/CHADSVASC? |
(CHADS2 score ≥2 under the2011 guideline2 and CHA2DS2-VASc score ≥2 under the 2014guideline1) |
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Themost common choices used for IV induction, probably in order of frequency, are |
Propofol, Thiopental, Etomidate, and Ketamine. |
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neuromuscular blocking agents |
succinylcholine (a depolarizing relaxer) or vecuronium (or any of the other -oniums or -uriums, which are all nondepolarizing relaxers). |
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steps in intubating |
preoxygenate, anesthetize, loss of lash reflex, neuromuscular blocking agent (relax), twitch, intubate |
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mechanism via which neurocardiogenic injury causes T-wave inversions |
catecholamine-mediated stunning of the myocardium, causing global repolarization abnormalities |