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44 Cards in this Set

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dosage chlorpromazine (thorazine) for intractable hiccups?

Initial oral dose is 25 mg three times daily for up to seven to ten days. The dose can be titrated up to 50 mg four times daily for improved control. Intravenous administration may be more effective, although the drug must be infused in 500 to 1000 mL saline with the patient in the supine position to prevent hypotension.

Dosage: metoclopramide for intractable hiccups

10 mg three or four times daily for up to 7 to 10 days

Side effect of metoclopramide

tardive dyskinesia

Side effects of chlorpromazine

Potential side effects with short-term usage include dystonic reactions and drowsiness. Long-term therapy increases the risk of tardive dyskinesia. Chlorpromazine is contraindicated in elderly patients with dementia.

physical maneuvers to stop hiccup

interrupting normal respiratory function (eg, breath holding, Valsalva maneuver) or nasopharyngeal/uvula stimulation (eg, sipping cold water, gargling with water)

a disorder of diminished motivation

abulia

components of the CAM ICU

acute onset or fluctuating course; inattention; disorganized thinking; altered LOC

requirements to diagnose delirium using CAM ICU method

1+2 and either 3 or 4

4 questions for disorganized thinking

will a stone float on water; are there fish in the sea; does 1 pound weigh more than 2 pounds; can you use a hammer to pound a nail?

slow regular breathing: diagnosis

drugs or hypothyroidism

components of brainstem testing in comatose

pupil size, pupillary light reflex, corneal, Doll's eye reflex; cough and gag; cold calorics

reason for sneaking from the side to test corneal reflex

If the patient blinks because they see you, you have tested CN II and VII. If they blink because they hear you, you have tested CN VIII (Acoustic) and VII.

cranial nerves involved in oculocephalic or Doll's eye reflex

CN VIII communicates to both CN III and VI in the pons to produce horizontal eye movement

Fever by IDSA criteria

38.3 or 101

7 important non infectious causes of fever in the icu

Drug fever, pancreatitis, acalculous cholecystitis, thyroid storm, adrenal insufficiency, transfusion reaction, post op fever (plus dvt)

Important causes of fever in the icu

IV Cath related infection, surgical site infection, cholangitis, endocarditis, c diff, si.usitis, pna, uti

When to treat fever with empiric antibiotics

Clinical condition deteriorating or in shock or neutropenic, with VAD, nee fever >102

Causes of post-op fever: pathophysio
due to tissue trauma with cytokine release, circulating bacterial endotoxins from endogenous gut flora




4 predominant infectious causes of postoperative fever
Surgical site infection, pneumonia, urinary tract infection, and intravascular catheter infection
most common noninfectious cause of postoperative fever
medication reaction; antimicrobial agents or heparin are the drugs most frequently implicated; other causes include pancreatitis, DVT, transfusion, gout
management of post-op fever
remove all unnecessary treatments (meds, NGT, IV cath, Foley)Acetaminophen no routine / empiric antibiotics unless hemodynamically unstable - and d/c after 2d if no source identified
criteria to safelyobserve patients without giving Abx in post-op neurosurg fever
<39.4ºC (102.9ºF)CSF WBC <7,500/µLCSF glucose >10 mg/dLdelirium, seizure, or surgical site inflammation

verapamil dose for rate control in Afib

240 to 480 mg daily in 3 to 4 divided doses; extended release: Usual maintenance dose range: 180 to 480 mg once daily

verapamil dose for PSVT prophylaxis

Immediate release: 240 to 480 mg daily in 3 to 4 divided doses

TCD mean velocity accepted as representing prob significant degree of arterial narrowing

100-120 cm/s mean velocity

increase in TCD implies

hyperaemia or vasospasm

what is the Lindegaard ratio?

ratio between mean velocity in MCA and mean velocity in cervical ICA, if 3 or more then the high intracranial velocity likely to be due to vasospasm

Labs to request for ISTH DIC scoring?

Platelets, D-dimer, PT, Fibrinogen

common causes of thrombocytopenia in the hospitalized patient

drugs, HIT, liver disease, multi-organ failure, DIC sepsis`

Less common: TTPHUS, lymphoma, leukemia, APAS, PNH, nutrient deficiency (B12, folate, copper)

asymptoamtic patient with thrombocytopenia, differentials?

immune thrombocytopenia (ITP), occult liver disease, HIV infection, myelodysplastic syndromes

drugs commonly associated with thrombocytopenia

heparin


beta lactam Abx, vancomycin, piperacillin, sulfonamides, bactrim, linezolid, levofloxacin?phenytoin, VPA, CMZ, haldol?


ibuprofen?, naproxen?, acetaminophen?


simvastatin?, furosemide?


ranitidine?

What is the ABCDE bundle?

Awakening and Breathing trials (AB) their coordination (C), choosing the right sedative when indicated (C), delirium monitoring and management (D) and early mobility (E)

the big 5 trials of interventional management of stroke in 2015

better results compared to IV tPA alone with intracranial ICA or MCA occlusions up to 6 hours of onset


MR CLEAN SWIFT PRIME EXTEND IA ESCAP and REVASCAT

esmolol for Afib in RVR - how to dose

load 0.5mg/kg x 1 min then 50 ug/kg/min x 4 mins; ual effective dose 50-200 ug/kg/min; 25 might be adequate

diltiazem for Afib in RVR - how to dose

0.25 mg/kg actual body weight over 2 minutes (average adult dose: 20 mg); ACLS guideline recommends 15-20 mg

DDx for sinus tach

4 big differentials: PE MI Sepsis Dehydration

Always treat: PainFeverAnxiety


anemia


Zebras: Hyperthyroidism Malignant hyperthermia

max value of CHADS/ CHADSVASC?

6 and 9

CHADS2 score components

prior strokeand transient ischemic attack, congestive heart failure anddysfunction, hypertension, age of 75 years or older, and diabetesmellitus (score range, 0-6)

CHADSVASC score components

increases the point value from 1 to 2 for age of 75 years andolder and adds elements for female sex, vascular disease,and age of 65 through 74 years (score range, 0-9)

when is OAC recommended for stroke prevention in CHADS/CHADSVASC?

(CHADS2 score ≥2 under the2011 guideline2 and CHA2DS2-VASc score ≥2 under the 2014guideline1)

Themost common choices used for IV induction, probably in order of frequency, are

Propofol, Thiopental, Etomidate, and Ketamine.

neuromuscular blocking agents

succinylcholine (a depolarizing relaxer) or vecuronium (or any of the other -oniums or -uriums, which are all nondepolarizing relaxers).

steps in intubating

preoxygenate, anesthetize, loss of lash reflex, neuromuscular blocking agent (relax), twitch, intubate

mechanism via which neurocardiogenic injury causes T-wave inversions

catecholamine-mediated stunning of the myocardium, causing global repolarization abnormalities