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49 Cards in this Set
- Front
- Back
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imiquimod
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interferon alpha
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primary cancer mohs vs excision 5 year cure rate
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99% mohs vs 93%
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recurrrent cancer mohs vs excision 5 year cure rate
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95% vs 80%
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Mohs anatomical sites
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face, scalp, genitlia, ditigs
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Mohs oculoplastic repair eyelid anatomic strucutures
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tarsal plate, levator muscle, or lacrimal apparatus esp canaliculus
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mohs eyelid important structure
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canaliculus
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ear skin cancer %
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6%
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ear skin cancer
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difficult eradication embryionic fusion planes periauricular area
predicatble pattern spread postauricular = ear preauricular = tragus, medial and superior helix if tragus can spread to ext tragus betwen tragal cartilage and parotid gland facial nerve |
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ear skin cancer tragus
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spread to facial nerve
neuropathic pain |
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postauricular skin cancer spread to
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ear
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preauricular skin cancer
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traugs
middle and superior helix if to tragus facial nerve neuropathic pain |
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mc place for bcc
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nose
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mc place for bcc recurrence
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nose
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upper lip
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bcc
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lower lip
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scc
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lower lip scc > 2 cm
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regional and metastatic spread
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higher cure rate penis
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glans or prepuce penis only and less than 1 cm
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Mohs degree of exicsion
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30 - 45 degree angle w 2 mm margin
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Mohs tissue frozen with?
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tetrafluroethylchloride or LN2
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sections intervals on slides mohs
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4 - 8 um
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Mohs stain
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hematoxylin and eosin or toluidine blue
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clear mouinting medium mohs
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cytoseal-60
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Ber-EP4
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cytokeratin stain
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HMB-45
MART-1 S-100 |
melanoma
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S-100
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perineural for granular cell tumors
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CEA
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extramammary paget's
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CD-34
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DFSP
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Special stains Mohs
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permanent sections
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Mohs tissue shrinkage
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10-20%
if larger technical error |
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mc cause of recurrence after mohs
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technical error
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look at first mohs
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vertical section
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increase inflammation mohs slides
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CLL 36%
solid organ transplant 13% normal 1% |
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mohs recut mark area with
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gentian violet
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topical eye anesthesia
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tetracaine
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bone specimens require
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ethylenediaminetetraacetic acid (EDTA) or similar sofening agent before sectioning
surgical delay |
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excision orbits
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castro-viejo needle holder w westcott tenotomy scissors 5 1/4
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BCC
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90% on head and neck
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BCCthermocouple
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-50 c or below
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BCC interferon alpha
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upregulation of CD95 induced spoptosis, recuritment of CD4+ Tcells, secretion of cytokines INF gamma and IL-2
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Imiquimod
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interferon alpha
once a day for 12 weeks 87% superficial BCC 65% for invasive BCC |
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BCC
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superficial
nodular ulcerative metatypical morphaform infiltrative |
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morpheaform
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yellow-red
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aggressive BCC
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ulcerative, metatypical, morphaform, infilatrative
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BCC cure
size of BCC |
< 1 cm 99.9%
1 to 2 cm 99.3% 2 to 3 cm 98.3% > 3 cm 84.3% |
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BCC mc location to spread from
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ear
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BCC mets through?
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blood to lungs, bone, skin
lymphatics |
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risk for BCC mets
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tumor ivnations cartilage, gone, skeletal mucle, or parotid gland, previous radiation therpay, previous trartment
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high risk mets BCC
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face, scalp, genitalia
mc ear |
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bcc mets chemo
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cisplastin
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