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48 Cards in this Set

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Anion gap and Osmolar gap metabolic acidosis with rectangular, envelope-shaped crystals in urine.

Ethylene glycol poisoning (anti-freeze)

(methanol and ethanol intox will cause anion, osmolar gap acidosis, too, but not the calcium oxalate crystals)
Painful 3rd trimester bleeding with normal ultrasound
Placental abruption
Precocious puberty, Pigmentation (cafe au lait spots), and Polyostotic fibrous dysplasia (multiple bone defects)
McCune-Albright syndrome
Occipital headaches, ataxia, facial weakness, gaze palsy (deviation of the eyes to left or right side)
Cerebellar hemorrhage
Older patient with back pain, hypercalcemia, anemia, and renal failure
Multiple Myeloma
Sudden onset of eye pain, photophobia, and a mid-dilated pupil:
Acute Glaucoma

a

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Exudative pleural effusion without evidence of infection
Malignancy

(breast cancer and lung cancer are the most common causes of malignant pleural effusions)
Young patient with a recent viral illness who presents with heart failure, chest pain, or arrhythmias:
Myocarditis

(which can progress to dilated cardiomyopathy, but most patient will have a t least a partial recovery of myocardial function)
Sickle cell patient with bacteremia/septic shock
Streptococcus pneumoniae

(encapsulated organism, and SC kids are predisposed to splenic auto-infarction!!!)
Sickle cell patient with diffuse musculoskeletal pain
Microvascular occlusions
(vasoocclusive crisis)
New mother will pain over lateral side of wrist
De Quervain tenosynovitis
HIV-patient with focal neurologic signs and multiple non-enhancing lesions in brain with no mass effect
Progrssive Multifocal Leukoencephalopathy

(caused by JC virus)

(on MRI it would show as multiple demyelinating non-enhancing lesions, with no mass effect)
Rapidly progressive skin lesions that develop into nontender nodules with central necrosis in an immunocompromised patients
Pseudomonas aeruginosa bactermia--caused Ecthyma gangrenosum
Thready pulses over radial arteries that disappear with deep inspiration
Pulsus paradoxus
Chest pain, signs of decreased cardiac output, and pulsus paradoxus following a viral infection
Cardiac tamponade resulting from acute pericarditis
Dizziness, hearing loss, and tinnitus
Meniere's disease
Chronic Tophaceous Gout )gouty arthritis)

Tophi can ulcerate a drain a chalky white material
Triad of findings in Disseminated Gonococcal infection (Gonococcemia)
1-Polyarthralgias
2-Tenosynovitis
3-Vesiculopustular skin lesions (painless) (2 to 10)
Lower abdominal pain that radiates to the thighs and back and begins a few hours prior to menses
Primary dysmenorrhea, caused by INCREASED PROSTAGLANDINS

(release of PGs during the breakdown of the endometrium ie before the actual bleeding starts)
Cyanotic infant with left axis deviation
Tricuspid atresia

(90% assoc'd with VSDs, 30% w/ TGA)
Pt from or ancestry of northern European ancestry with megaloblastic anemia, shiny tongue (atrophic glossitis), vitiligo, and thyroid disease, possibly with thrombocytopenia and/or leukopenia
Pernicious anemia = most common cause of B12 deficiency in whites of northern European ancestry, and they frequently have tiger autoimmune diseases like thyroid disease and vitiligo

(usu neuro sx there, too, but not always)
Macrocytic anemia in a sickle cell patient
Folate deficiency

(b/c chronic hemolysis and bone marrow tries to make more RBC to compensate and uses up folate...so sickle cell patients should be on daily folate supplements)

*Note: if on hydroxyurea, this can also cause macrocytosis
Sudden onset of photopsia (flashes of light) and floaters, with description of "a curtain coming down over my eyes"
Retinal detachment

Teenage girl with primary amenorrhea, fully-deveoped breasts, absent pubic and axillary hair, short/blind-ended vagina, no uterus on ultrasound

Androgen Insensitivity Syndrome--karyotype would show 46 XY and labs would show elevated testosterone for a girl (but normal amount for a boy)

-Caused by defective androgen receptors resulting in androgen resistance in peripheral tissues

-Mullerian Inhibiting Factor is still present as it was produced by the testes (which are likely in the abdomen or inguinal canal) and that is why no uterus cuz MIF inhibits the formation of uterus, fallopian tibes, and upper part of vagina.

-No pubic or axillary hair because b/c ts production is dependent on testosterone, and its receptor are resistant/insensitive to testosterone.
Female delivered baby 12 hours ago and now has temp of 100.4 and WBC 11,000, with shaking chills during and 10 min following delivery; uterus is found to be firm and nontender
Normal postpartum presentation

In the immediate postpartum period, a low-grade fever, leukocytosis, and vag discharge are normal findings.

It would be worrisome if the lochia is foul-smelling or if the uterus is tender--then you'd be worried about endometritis.
Smoker with whitish, localized plaques in oral mucosa with a granular texture and not removed by scraping
Leukoplakia--> has a risk of transformation into squamous cell carcinoma

-A biopsy should be done to exclude cancer, but at this point the most likely cause of this lesion is leukoplakia
Fall on an outstretched hand with tenderness in anatomic snuffbox

(if + displacement, then open reduction and internal fixation is required)
Scaphoid fracture--risk of nonunion so wrist should be immobilized for 6-10 weeks
HIV patient--pain with swallowing, has white plaques over pharynx, CD4 of 50, on TMP-SMX
Candida Esophagitis--tx with fluconazole
Venous stasis ulcers, form chronic venous valvular insufficiency

typically present on lower leg, above the ankle
Middle age patient with weight loss & jaundice
Pancreatic cancer

--other signs and sx:
palpable, nontender gallbladder (Courvoisier sign),
-migratory thrombophlebitis (Trousseau syndrome),
-epigastric pain,

Fever, and an erythematous area on body which is swollen, painful, hyperesthetic to touch, and has a sharp demarcation separating the red area from te normal skin...with local lymphadenopathy

ERYSIPELAS = a superficial thrombophlebitis caused by Strep pyogenes
Joint pain, splenomegaly, and neutropenia
Felty's syndrome

(anemia and leukopenia often present as well)

(possible late consequence in rheumatoid arthritis)

Painful oral and genital ulcers and erythema nodosum

Behcet syndrome

also commonly uveitis/eye lesions, arthritis, or other skin lesions
Alcoholic smoker with combination of elevated JVP, hepatomegaly, ascites, and lower extremity edema, without evidence of pulmonary congestion
Isolated Right Heart Failure secondary to Cor Pulmonale from COPD

Other findings that may be present: right-sided S3, right ventricular heave, ascites

alcoholic part is there to throw off in thinking about liver issues from alcohol, but here there is hepatomegaly because of congestion whereas in alcohol cirrhosis there would be a small and firm fibrosed liver
RUQ or epigastric pain in ICU patient with severe trauma/sepsis/etc
Acalculous cholecystitis

emergent tx is percutanoeous cholecystostomy (perc drain) followed by cholecystectomy once patient stabilizes
6 year old with rash, joint pain, abdominal pain, and hematuria
Henoch-Schonlein Purpura

typically purpuric rash, but apparently the question can say a maculopapular rash
on lower extremities and btutocks usually

Pt undergoes surgical repair of an AAA, then post-op he develops LLQ pain with bloody diarrhea. CT shows thickening of the rectosigmoid junction and colonoscopy shows ulecrations in that area but above and below it are normal

Ischemic colitis

Bowel ischemia may complicate up to 7% of procedures on the aortoiliac vessels and most commonly affects the distal left colon
Common causes: loss of collateral circa, manip of vessels with the surg instruments, prolonged aortic clamping, and impaired blood flow thru the inferior mesenteric artery.
After blunt trauma to the chest, if an x-ray shows a deviated mediastinum with a mass in the left lower chest, one should suspect:
A diaphragmatic perforation with herniation of abdominal viscera

Dx with barium swallow or CT scan with oral contrast
Elevated direct bilirubin and liver biopsy shows dark granular pigment in the hepatocytes
Dubin-Johnson syndrome

(DJ likes rainbows!)

Pt complains of blurred vision, cough, and shortness of breath, along with mild fevers and malaise. CXR shows bilateral reticulonodular infiltrates & hilar adenopathy.

SARCOIDOSIS

◆ Most common complaints: cough, dyspnea, fever, wt loss.
◆ Lungs most freq involved organ system--CXR will show B/L hilar LAD &/or B/L reticulonodular infiltrates/opacities (ground glass appearance)
◆ Eyes--Anterior uveitis (silt-lamp shows leukocytes in ant chamber)
◆ Skin--Erythema nodosum
◆Joints--Arthritis
PainFUL genital ulcer(s)
"Holy Crap that hurts!"

Herpes & Chancroid

The others are painLESS--Granuloma inguinale, Lymphogranuloma venerum, & Syphilis ("Gross Lesions without Stress"...ie no pain)
PainLESS genital ulcer(s)
"Gross Lesions without Stress" (i.e. no stress=no pain)

Granuloma inguinale
Lymphogranuloma venerum
Syphilis

Syphilis vs Granuloma inguinale = no LAD in granuloma inguinale and it has beefy red base

Erythematous papules with a central scale and a "sandpaper-like" texture on palpation

Actinic keratoses

2-hour old male LGA newborn, uncomplicated pregnancy, fine at birth but now 2 hours later--worsening cyanosis and respiratory distress, not relieved by oxygen. Has a normal S1 and a single & loud S2, with no murmur.

Transposition of the Great Vessels

(the foramen ovale and ductus arteriosus begin to close after birth, so decreased mixing of oxygenated with non-oxygenated blood

Presents in first few hours of life

Give PGE1 IV immediately and then surgical correction
ICU patient with low T3, normal T4, and normal TSH
Sick euthyroid syndrome

any pt with acute severe illness can develop these abnormal labs which we call sick euthyroid syndrome (decreased peripheral conversion of T4 to T3 b/c under crazy stress, cytokines, etc)
Newborn male with oliguria and a midline mass in lower abdomen
Posterior Urethral valves

= most common cause of congenital urethral obstruction

the midline lower abdom mass likely represents a distended bladder

next step = VCUG to confirm dx

Ipsilateral headache and ipsilateral Horner's syndrome

Carotid artery dissection (sympathetic nerves travel along the carotid, can still have sweating if partial horners as sweat fibers only on ext carotid)