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115 Cards in this Set

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Posthepatic venous thrombosis. Abdominal pain, ascites, hepatosplenomegaly. Same as CHF except no JVD.
Budd Chiari Syndrome
Achilles tendon xanthoma
Familial hypercholesterolemia
Meningococcemia, Adrenal Hemorrhage, hypotension, DIC.
Waterhouse-Friderichsen Syndrome. Neisseria Meningitidis Sepsis.
Arachnodactyly, lens dislocations, aortic dissection, hyperflexible joints.
Marfan's Syndrome. Fibrillin Defect.
Vertebral tuberculosis. Back Pain, fever, night sweats, weight loss.
Pott's Disease
Fever, night sweats, weight loss.
TB and B symptoms of Hodgkins
Babinski's sign
UMN lesion. Big toe extension/fanning upon plantar scrape. Hyperreflexia.
Sarcoidosis
Noncaseating granulomatosis. Bilateral hilar adenopathy, uveitis.
Osteogenesis Imperfecta
Blue Sclera. Type 1 collagen defect.
Burton's Line
Lead poisoning. Bluish line on gingiva.
Increased hat size, bone pain, bone enlargement, arthritis.
Paget's disease of bone. Increased osteoblast and osteoclast activity (bone turnover).
Café au lait spots, lisch nodules (iris hamartoma).
Neurofibromatosis type I
Café au lait spots, lisch nodules (iris hamartoma), AND bilateral acoustic neuromas.
Neurofibromatosis type II
Calf pseudohypertrophy, Gower's sign (child uses hands to stand up from squat).
Duchene's Muscular Dystrophy. X linked recessive Dystrophin defect.
Cherry red spot on macula.
Tay Sachs (ganglioside accumulation), Niemann-Pick (lysosomal storage disease, Central Retinal Artery Occlusion
Autoimmune mediated post MI fibrinous pericarditis (weeks after MI). Chest pain, pericardial effusion/friction rub, persistent fever following MI.
Dressler's Syndrome
Child with fever develops red rash on face that spreads to body.
"Slapped Cheeks" Parvovirus B19.
Huntington's Disease
Autosomal dominant trinucleotide (CAG) repeat expansion. 3 C's, Chorea, Crazy, Caudate degeneration, ACh deficiency.
Chronic exercise intolerance with myalgia, fatigue, painful cramps.
McArdle's Syndrome. Muscle Phosphorylase deficiency.
Cold intolerance
Hypothyroidism
Patent Ductus Arteriosus
Close with indomethacin, open with misoprostol. Continuous "machinery" heart murmur.
Myxedema
Grave's Disease (autoimmune hyperthyroidism) OR Hypothyroidism, cutaneous/dermal edema due to connective tissue deposition.
Dark purple skin/mouth nodules.
Kaposi's Sarcoma (Aid's patients, HHV-8, gay men)
Kussmaul breathing
Diabetic ketoacidosis. Deep, labored breathing/hyperventilation to blow off CO2.
Pellagra
Niacin (Vit B3) deficiency. 3 D's, Dermatitis, dementia, diarrhea.
Wet Beriberi
Thiamine (vit B1 deficiency). Dilated cardiomyopathy, edema, polyneuropathy.
Pasteurella multocida
Dog or cat bite with infection/cellulitis.
Dry eyes, dry mouth, arthritis (autoimmune destruction of lacrimal and salivary glands)
Sjogren's syndrome
Dysphagia (esophageal webs), glossitis, iron deficiency anemia (may progress to esophageal squamous cell carcinoma)
Plummer Vinson Syndrome
Ehlers-Danlos Syndrome
Elastic skin, hypermobility of joints, collagen type 3 defect
Abdominal metastasis. Enlarged, hard left supraclavicular node.
Virchow's Node
Chvostek's Sign
Hypocalcemia. Facial muscle spasm upon tapping. Ch for cheek and chvostek's sign.
Gall stones, gall bladder, Fat, Female, Forty, and Fertile. 4 F's.
Acute cholelithiasis (bile duct blockage)
Jarisch-Herxhimer reaction
Rapd lysis of spirochetes results in toxin release. Fever, chills, headache, myalgia following antibiotic trtmnt for syphilis.
Fever and 3 C's. cough, conjuncitivitis, coryza, diffuse rash.
Measles (Morbillivirus)
B symptoms (lymphoma) OR TB
Fever, night sweats, weight loss.
Peyronie's Disease
Connective tissue disorder, fibrous plaques in soft tissue of penis.
Gout, Mental retardation, self-mutilating behavior in a boy.
Lesch-Nyhan Syndrome. HGRPT Deficiency (enzyme of purine salvage).
Green rings around periph cornea.
Kayser-Fleischer Rings. Copper accumulation from Wilson's.
Hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands
Peutz-Jeghers Syndrome. Genetic benign polyposis can cause bowel obstruction and increased cancer risk.
Hepatosplenomegaly, osteoporosis, neurologic symptoms
Gaucher's Disease. Glucocerebrosidase deficiency.
Hereditary nephritis, sensorineural hearing loss, cataracts.
Collagen mutation. Can't see, can't pee, can't hear. Alport's Syndrome.
Hyperphagia, hypersexuality, hyperorality, hyperdocility.
Kluver-Bucy syndrome. Bilateral amygdala lesion.
Hypertensin, hypokalemia, metabolic acidosis.
Conn's syndrome. Primary hyperaldosteronism.
"Blue Bloater"
Chronic bronchitis: hyperplasia of mucous cells. Hypoxemia, polycythemia, hypercapnia.
Indurated, ulcerated genital lesion (non painful).
Chancre. Primary Syphilis, Treponema Pallidum.
Niemmann-Pick Disease
Genetic Sphingomyelinase deficiency. Infant with failure to thrive, hepatosplenomegaly, neurodegeneration, cherry red spot on macula.
Infant with hypoglycemia, failure to thrive, hepatomegaly. No glycogenolysis.
Cori's Disease. Debranching enzyme deficiency.
Infant with hypoglycemia, fialure to thrive, hepatomegaly. Absent gluconeogenesis, absent glycogenolysis.
Von Gierl's Disease
Infant with micrcephaly, rocker-bottom feet, structural heart defect
Edward's Syndrome. Trisomy 18
Jaundice, RUQ pain, fever.
Charcot's triad (Ascending cholangitis)
Keratin Pearls
Squamous Cell Carcinoma
Large rash with Bull's eye appearance.
Erythema chronica migrans. Tick bite, borrelia, lyme disease.
Male child, recurrent infections, no mature B cells. X-linked agammaglobulinemia.
Bruton's disease. Boys, B Cells for Bruton's.
Defect in platelet aggregation due to lack of GpIIb/IIIa. Mucosal bleeding and prolonged bleeding time.
Glanzmann's Thrombasthenia
Multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumary teeth.
Garder's Syndrome (genetic disorder). Predisposes to colon cancer
Hemoptysis and glomerular disease. Necrotizing vasculitis (lungs) and necrotizing glomerulonephritis.
Wegener's and Goodpasture's syndromes. Wegener's also has sinus/palate problems.
Waiter's tip. Neonate with arm paralysis and clavicle fracture after birth.
Erb-Duchenne Palsy. Superior trunk (C5-6) brachial plexus injury.
No lactation postpartum, absent menstruation, cold intolerance.
Sheehan's syndrome. Pituitary infarction. Hemorrhage during birth leads to hypotension leads to pituitary infarction.
Nystagmus, intention tremor, scanning speech
Charcot's triad (MS)
Oscillating slow/fast breathing.
Cheyne-Stokes Resperiations. Caused by central apnea in CHF or increased ICP.
Painful blue fingers/toes, hemolytic anemia.
Cold Agglutinin Disease (IgM). Caused by autoimmune hemolutic anemia (Mycoplasma pneumoniae) or infectious mononucleosis (EBV)
Painful, pale, cold fingers/toes.
Raynaud's syndrome. Vasospasm in extremity.
Painful, raised red lesions on palms and soles.
Osler's node. Infective Endocarditis.
Painless Jaundice
Cancer of the pancreatic head obstructing bile duct
IgA vasculitis affecting skin and kidneys. Palpable purpura, joint pain, abdominal pain (child), renal disease
Henoch-Schlonlein purpura
MEN 1 (Multiple Endocrine neoplasia). Pancreatic, pituitary, parathyroid tumors.
Wermer's Syndrome
Emphysema: centroacinar (smoking), panacinar (alpha1-antitrypsin deficiency). Pink complexion, dyspnea, hyperventilation.
"Pink puffer"
Mosaic G-protein signaling mutation. Polyostotic fibrous dysplasia, precocious puberty, café au lait spots, short stature in a young girl, multiple unilateral bone lesions.
McCune-Albright syndrome
Proximal tubular reabsorption defect, get rid of too much stuff. Polyuria, acidosis, growth failure, electrolyte imbalances.
Fanconi's Syndrome
Sympathetic chain lesion caused by Pancose tumor in apex of lung. Ptosis, miosis, anhidrosis (no sweat).
Horner's Syndrome
Neurosyphilis, pupil accomodates but doesn't react.
Argyll Robertson Pupil (Prostitute's pupil)
Autoimmune acute inflammatory demyelinating abnormality. Rapidly progessive leg weakness that ascends following GI/upper respiratory infection.
Guillan Barre Syndrome
Rash on Palms and Soles.
Secondary Syphilis, RMSF, Coxsackie A virus (hand foot mouth)
Neurtophil chemotaxis abnormality. Recurrent colds, unusual eczema, high IgE.
Hyper IgE (Job's syndrome)
Red "Currant Jelly" Sputum.
Klebsiella pneumoniae
Red, itchy, swollen rash of nipple/aereola
Paget's Disease of Breast indictating underlying neoplasm
Red urine in the morning.
Paroxysmal noctural hemoglobinuria. Lack CD55 and CD59 so attack own RBCs.
Renal cell carcinoma, hemangioblastomas, angiomatosis, pheochromocytomas.
von-Hippel Lindau disease. Dominant tumor suppressor gene mutation.
Resting tremor (pill roll tremor), rigidity, akinesia, postural instability
Parkinson's disease. Nigrostriatal dopamine depletion.
Restrictive Cardiomyopathy (juvenile cardiomegaly), exercise intolerance
Pempe's Disease (lysosomal glucosidase deficiency)
Retinal hemorrhages with pale centers
Roth's Spots (bacterial endocarditis)
Severe RLQ pain with rebound tenderness
McBurney's Sign. Appendicitis.
Short stature, increased incidence of tumors/leukemia, aplastic anemia
Fanconi's anemia (genetically inherited can progress to AML)
Single palm Crease
Symian crease, Down Syndrome
Severe Jaundice in neonate
Crigler-Najjar Syndrome. Congenital unconjugated hyperbilirubinemia
Situs inversus (organs reversed), chronic sinusitis, bronchiectasis, infertility
Kartagener's syndrome. Dynein defect affecting cilia.
Skin hyperpigmentation
Addison's Disease. Primary adrenocortical insufficiency of autoimmune or infectious etiology.
Slow progressive muscle weakness in boys
Becker's Muscular Dystrophy. X-linked defective dystrophin, less severe than Duchenne's.
Small, irregular red spots on buccal/lingual mucosa with blue-white centers
Koplik Spots (Measles)
Small, nontender, erythematous lesions on palms/soles
Janeway Lesions (infective endocarditis)
Smooth, flat moist white lesions on genitals
Condylomata lata. Secondary syphilis.
Splinter hemorrhages in fingernails
Bacterial endocarditis
Strawberry Tongue
Scarlet Fever (GAS), Kawasaki's disease
Smooth Glossy Tongue, Glossitis
Vitamin B Deficiency
Streak ovaries, horseshoe kidney, coarctation of the aorta
Turner's Syndrome. XO (45 chromosomes), short stature, webbed neck, lymphedema.
Sudden Swollen/big toe joint, tophi
Gout/Podagra (hyperurecimia). Yellow and parrallel.
Systolic ejection murmur (late), cresccendo-decrescendo
Aortic Valve Stenosis
Early systolic ejection murmor in mitral/tricuspid area
Aortic Regurgitation
Swollen gums, mucous bleeding, poor wound healing, spots on skin
Scurvy. Vitamin C deficiency. Can't hydroxylate proline/lysine for collagen synthesis.
Swollen hard painful finger joints.
Osteoarthritis
Osteophytes on PIP in osteoarthritis
Brouchard's Nodes
Osteophytes on DIP in osteoarthritis
Heberden's Nodes
Medulary Thyroid, parathyroid, adrenal tumors
Sipple's Syndrome (MEN 2A) Pheochromocytoma.
Ulcerated genital lesion with exudate (painful)
Chancroid (Haemophilus ducreyi)
Unilateral face drooping
Bell's palsy (LMN CNVII Palsy).
Upper and Lower drooping of face
Bilateral Bell's palsy seen in Guillan Barre or Lyme Disease (Borrelia Burdorferi)
Urethritis, conjunctivitis, arthritis in a male. Can't see can't pee can't climb a tree.
Reiter's Syndrome (HLA-B27). PAIR= seronegative spondyloarthropathies. Psoriatic arthritis, ankylosing spondylitis, IBD, Reiter's syndrome.
Vascular Birthmark (Port Wine stain)
Hemangioma. Benign but associated with Sturge Weber Disease on opthalmic trigeminal distribution.
Vasculitis from exposure to endotoxin causing glomerular thrombosis
Shwartzman Reaction following second exposure to endotoxin.
Vomiting blood following esophagogastric lacerations.
Mallory-Weiss Syndrome. Alcoholics and eating disorders.
Waxy castas with low urine flow
End Stage Renal Disease
WBC Casts in urine
Acute Pyelonephritis
Weight loss, diarrhea, arthritis, fever, adenopathy
Whipple's disease (Tropheryma whippelii)
What is associated with adult polycystic kidney disease
Berry Aneurysm rupture to subarrachnoid hemmorhage.