Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key


Play button


Play button




Click to flip

79 Cards in this Set

  • Front
  • Back
Ichthyosis vulgaris
inc thickness of stratum corneum; absent granular layer
Solar lentigo
"liver spot" in elderly; increased melanocytes
Senile purpura
trauma to fragile vessels on dorsum of hands; normal finding in elderly
Acute eczema
weeping rash with vesicles
Chronic eczema
dry, thickened, pruritic skin
Atopic dermatitis
dry skin, eczema (type I reaction); children- face, intertriginous areas
Allergic contact dermatitis
type IV hypersensitivity; poison ivy, nickel rash
Contact photodermatitis
tetracycline; rash in sun exposed areas
Superficial dermatophytoses
KOH preparation shows fungi located in stratum corneum
Tinea capitis
Trichophyton tonsurans MCC (negative Wood's lamp)
Tines capitis child with dog
Microsporum canis (positive Wood's lamp)
Tinea versicolor
hypopigmentation; Malassezia furfur; "spaghetti" (hyphae)/"meatball" KOH
Seborrheic dermatitis
dandruff; Malassezia furfur
Molluscum contagiosum
poxvirus; bowel-shaped with central depression filled with keratin
Koplik's spots; Warthin-Finkeldey giant cells
teratogenic; rash; postauricular adenopathy; arthritis in adults
"slapped face"; RBC aplasia, aplastic anemia (HbSS), spontaneous abortions, arthritis
HSV-6; high fever and then rash
Toxic shock syndrome
toxin-producing S. aureus; tampon wearing; hypotension, desquamating rash
Scarlet fever
group A streptococcus with erythrogenic toxin; strawberry tongue
Actinic (solar) keratosis
precursor for squamous cell carcinoma; recur when scrapped off
elevated salmon-colored plaques covered by silver-colored scales; nail pitting
Pityriasis rosea
herald patch followed by rash in lines of cleavage
chickenpox; rash at different stages; Reye syndrome association
Herpes zoster
vesicular rash following a sensory dermatome
HSV and Varicella-zoster virus
remain latent in sensory ganglia
group A streptococcus; honey crusted lesions on face
Pemphigus vulgaris
autoimmune disease; IgG antibodies against intercellular attachment sites
Pemphigus vulgaris
intraepidermal bullae; acantholytic cells; row of tombstones
Bullous pemphigoid
autoimmune disease; IgG antibodies against basement membrane
Bullous pemphigoid
subepidermal bullae
Pemphigus vulgaris/bullous pemphigoid
type II hypersensitivity
Dermatitis herpetiformis
autoimmune disease; IgA ICs; subepidermal bullae with neutrophils
Dermatitis herpetiformis
association with celiac disease
Erythema multiforme
vesicles and bullae; bullseye appearance
Risk factors for Erythema multiforme
drugs, M. pneumoniae infection
Stevens Johnson syndrome
erythema multiforme involving mouth
Acne vulgaris
androgen dependent (receptor on sebaceous glands)
Acne vulgaris
Propionibacterium acnes lipases produce fatty acids causing inflammation
Acne rosacea
pustular, erythematous lesion on face resembling malar rash
type I and III reactions; type I due to mast cell release of histamine (drugs, fire ant bites)
subcutaneous swelling
causes of angioedema
ACE inhibitor (bradykinin); Cl esterase inhibitor deficiency (C2 and C4 decreased)
traumatic implantation Sporothrix fungus into subcutaneous tissue
Causes of Sporotrichosis
rose gardener, lobster fisherman (sphagnum moss)
S/S of Sporotrichosis
chain of subcutaneous nodules
Tuberculoid leprosy
intact cellular immunity (positive lepromin skin test); granulomas; no organisms
S/S of Tuberculoid leprosy
autoamputation of digits; skin depigmentation and anesthesia
Lepromatous leprosy
defective cellular immunity (negative lepromin skin test); no granulomas
S/S of Lepromatous leprosy
leonine face, erythema nodosum during treatment
Histology of Lepromatous leprosy
Grenz zone (zone free organisms) foamy macrophages with organisms
Rx for Lepromatous leprosy
Erythema nodosum
painful nodule on shins; subcutaneous fat inflammation
Associations with Erythema nodosum
coccidioidomycosis, TB, leprosy
benign neoplasm; mimics squamous cancer; spontaneously resolves
UVB light cancers
basal cell carcinoma, squamous cell carcinoma, malignant melanoma
autoimmune destruction melanocytes producing skin depigmentation
Seborrheic keratosis
pigmented, wart-like lesion; "stuck on" appearance
Leser-Trelat sign
multiple outcroppings seborrheic keratosis; consider stomach cancer
Acanthosis nigricans
verrucoid pigmented lesion usually in axilla; associated with gastric cancer
pregnancy mask due to increased melanocytes
Nevocellular nevus
benign pigmented tumor modified melanocytes
Histology of Nevocellular nevus
nevus cells proliferate along basal cell area, dermis, or both places
Dysplastic nevus
precursor for malignant melanoma
Malignant melanoma
malignant tumor of melanocytes; most rapidly increasing cancer worldwide
ABCD for melanoma
A, asymmetry; B, irregular border; C, color change; D, increased diameter
Risk factors for melanoma
severe sunburn at early age (MC), dysplastic nevi
Radial growth phase
spreads laterally in epidermis/superficial dermis but does not result in metastasis
Vertical growth
malignant cells penetrate into dermis; potential for metastasis
Lentigo malignant melanoma
face of elderly
Superficial spreading melanoma
lower extremities, back
Nodular melanoma
aggressive tumor with no radial growth phase
Acral lentiginous melanoma
palms, soles, under nails; may occur in blacks
Prognosis in melanoma
depends most on depth of invasion
Prevention of melanoma
sunscreen > 15
Porphyria cutanea tarda
photosensitive bullous disease; deficiency uroporphyrinogen decarboxylase
S/S of Porphyria cutanea tarda
hypertrichosis, fragile skin, port wine colored urine (uroporphyrins)
Black widow (Latrodectus) envenomation
neurotoxin; abdominal muscle cramps
Brown recluse (Loxosceles) envenomation
necrotoxin; skin ulcer