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82 Cards in this Set

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vancomycin
glycopeptide antibiotic

inhibit cell wall synthesis
(binds D-Ala-D-Ala terminus
teicoplanin
glycopeptide antibiotic

inhibit cell wall synthesis
(binds D-Ala-D-Ala terminus
penicillin
beta lactam

inhibit cell wall synthesis
(bind PBPs)
cephalosporin
beta lactam

inhibit cell wall synthesis
carbapenem
beta lactam

inhibit cell wall synthesis
monobactam
carbepenem
beta lactam

inhibit cell wall biosynthesis/membrane potential
penicillin G
penicillin- a beta lactam

bind PBP
penicllin V
penicllin- a beta lactam

bind PBP
procaine
organic base that delays absorption of penicilin from intramuscular site
benathine
organic base that delays absorption of penicillin from intramuscular site
probenecid
competitive blocker of tubular secretion of organic acid that delays elimination of penicillin
methicllin
penicillinase-resistant penicillin - a beta lactam
nafcillin
penicillinase resistant penicillin- a beta lactam
cloxacillin
penicillinase resistant penicllin- a beta lactam
ampicillin
extended range penicillin- a beta lactam
amoxicillin
extended range penicillin- a beta lactam
carbenicillin
an anti-pseudomonal penicillin carboxylated derivative of amoxicillin- a beta lactam
ticarcillin
an anti-pseudomonal penicillin carboxylated deriviative of amoxacillin- a beta lactam
azlocillin
anti-pseudomonal penicillin N-acyl derivative (ureidopencillin)
mezlocillin
anti-pseudomonal penicillin N-acyl derivative (ureidopencillin)
pipericillin
anti-pseudomonal penicillin N-acyl derivative (ureidopencillin)
augmentin
amoxicillin + clavulanate
timentin
ticarcillin + clavulanate
unasyn
ampicillin + sulbactam
zosyn
pipericillin + tazobactam
cefadroxil
1st gen cephalosporin- a beta lactam

inhbit cell wall synthesis
cephalexin
1st gen cephalosporin- a beta lactam

inhibit cell wall synthesis
cefazolin
1st gen cephalosporin- a beta lactam

inhbit cell wall synthesis
cephadrine
1st gen cephalosporin- a beta lactam

inhbit cell wall synthesis
cefotetan
2nd gen cephalosporin
- a beta lactam

inhibits cell wall synthesis
INC activity against gram neg
DEC activity against gram pos
cefoxitin
2nd gen cephalosporin
- a beta lactam

inhibits cell wall synthesis
INC activity against gram neg
DEC activity against gram pos
cefuroxime
2nd gen cephalosporin
- a beta lactam

inhibits cell wall synthesis
INC activity against gram neg
DEC activity against gram pos
cefuroxime axetil
2nd gen cephalosporin
- a beta lactam

inhibits cell wall synthesis
INC activity against gram neg
DEC activity against gram pos
carbacephem
2nd gen cephalosporin
- a beta lactam

inhibits cell wall synthesis
INC activity against gram neg
DEC activity against gram pos
cefotaxime
3rd gen cephalosporin
- a beta lactam

inhibits cell wall synthesis
Good CNS penetration
cefpodoxime
3rd gen cephalosporin
- a beta lactam

inhibits cell wall synthesis
Good CNS penetration
ceftazidime
3rd gen cephalosporin
- a beta lactam

inhibits cell wall synthesis
Good CNS penetration
ceftriaxone
3rd gen cephalosporin
- a beta lactam

inhibits cell wall synthesis
Good CNS penetration
cefepime
4th gen cephalosporin
-a beta lactam

inhibits cell wall synthesis
imipenem
carbapenem
-a beta lactam

inhibits cell wall synthesis
meropenem
carbepenem
-a beta lactam

inhibits cell wall synthesis
ertapenem
carbepenem
-a beta lactam

inhibits cell wall synthesis
monobactam
carbepenem
-a beta lactam

inhibits cell wall synthesis
daptomycin
lipopeptide

inhibit cell membrane potential
linezolid
oxazoladinone

inhibit protein synthesis
(binds 23S and prevents formation of 70S)
tetracycline
tetracycline

inhibit protein synthesis
(bind 30S and prevent binding of aminoacyl-tRNA during protein synthesis)
doxycycline
tetracycline

inhibit protein synthesis
(bind 30S and prevent binding of aminoacyl-tRNA during protein synthesis)
minocycline
tetracycline

inhibit protein synthesis
(bind 30S and prevent binding of aminoacyl-tRNA during protein synthesis)
streptomycin
aminoglycoside

inhibit protein synthesis
(bind 30S- irreversibly inhibit protein synthesis)
neomycin
aminoglycoside

inhibit protein synthesis
(bind 30S- irreversibly inhibit protein synthesis)
gentamycin
aminoglycoside

inhibit protein synthesis
(bind 30S- irreversibly inhibit protein synthesis)
kanamycin
aminoglycoside

inhibit protein synthesis
(bind 30S- irreversibly inhibit protein synthesis)
tobramycin
aminoglycoside

inhibit protein synthesis
(bind 30S- irreversibly inhibit protein synthesis)
sisomicin
aminoglycoside

inhibit protein synthesis(bind 30S- irreversibly inhibit protein synthesis)
amikacin
aminoglycoside

inhibit protein synthesis
(bind 30S- irreversibly inhibit protein synthesis)
netilmicin
aminoglycoside

inhibit protein synthesis
(bind 30S- irreversibly inhibit protein synthesis)
chloramphenicol
bind 50S

inhibit protein synthesis
macrolide
MLS group

inhibit protein synthesis
lincosamide
MLS group

inhibit protein synthesis
type B streptogramins
MLS group

inhibit protein synthesis
ketolide
MLS group

inhibit protein synthesis
erythromycin
macrolide
-MLS group

inhibit protein syntheis
(binds 50S and inhibits translocation)
clarithromycin
macrolide
-MLS group

inhibit protein syntheis
(binds 50S and inhibits translocation)
azithromycin
macrolide
-MLS group

inhibit protein syntheis
(binds 50S and inhibits translocation)
clindamycin
lincosamide
-MLS group

inhibits protein synthesis
(binds P and A site in 50S)
synecid
combo of streptogramin B with streptogramin A

inhibits protein synthesis
quinupristin
streptogramin B
-MLS group

inhibits protein synthesis
(binds 50S and inhibits translocation)
dalfopristin
streptogramin A

inhibits protein synthesis
(induces conformation change in 50S, enhancing binding of quinupristin)
telithromycin
ketolide
-MLS group

inhibits protein synthesis
sulfisoxazole
sulfonamide

inhibit nucleic acid synthesis
(compete w/ PABA for dihydropteroate synthase)
sulfamethoxazole
sulfonamide

inhibit nucleic acid synthesis
(compete w/ PABA for dihydropteroate synthase)
trimethoprim
benzylpyrimidine

inhibit nucleic acid synthesis
(inhibits bacterial dihydrofolate reductase)
pyrimethamine
benzylpyrimidine

inhibit nucleic acid synthesis
(inhibits bacterial dihydrofolate reductase)
norloxacin
fluoroquinolone

inhibits DNA gyrase in gram neg
inhibits topoisomerase in gram pos
ciprofloxacin
fluoroquinolone

inhibits DNA gyrase in gram neg
inhibits topoisomerase in gram pos
ofloxacin
fluoroquinolone

inhibits DNA gyrase in gram neg
inhibits topoisomerase in gram pos
levofloxacin
fluoroquinolone

Inhibits nucleic acid synthesis
(inhibits DNA gyrase in gram neg
inhibits topoisomerase in gram pos)
lomefloxacin
fluoroquinolone

Inhibits nucleic acid synthesis
(inhibits DNA gyrase in gram neg
inhibits topoisomerase in gram pos)
sparfloxacin
fluoroquinolone

Inhibits nucleic acid synthesis
inhibits DNA gyrase in gram neg
inhibits topoisomerase in gram pos
pefloxacin
fluoroquinolone

inhibits DNA gyrase in gram neg
inhibits topoisomerase in gram pos
metronidazole
nitroimidazole

inhibit DNA replication (nucleic acid synthesis)
rifaximin
rifamycin

inhibits nucleic acid synthesis
(inhibits bacterial RNA synthesis)