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82 Cards in this Set
- Front
- Back
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vancomycin
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glycopeptide antibiotic
inhibit cell wall synthesis (binds D-Ala-D-Ala terminus |
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teicoplanin
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glycopeptide antibiotic
inhibit cell wall synthesis (binds D-Ala-D-Ala terminus |
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penicillin
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beta lactam
inhibit cell wall synthesis (bind PBPs) |
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cephalosporin
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beta lactam
inhibit cell wall synthesis |
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carbapenem
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beta lactam
inhibit cell wall synthesis |
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monobactam
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carbepenem
beta lactam inhibit cell wall biosynthesis/membrane potential |
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penicillin G
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penicillin- a beta lactam
bind PBP |
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penicllin V
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penicllin- a beta lactam
bind PBP |
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procaine
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organic base that delays absorption of penicilin from intramuscular site
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benathine
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organic base that delays absorption of penicillin from intramuscular site
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probenecid
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competitive blocker of tubular secretion of organic acid that delays elimination of penicillin
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methicllin
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penicillinase-resistant penicillin - a beta lactam
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nafcillin
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penicillinase resistant penicillin- a beta lactam
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cloxacillin
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penicillinase resistant penicllin- a beta lactam
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ampicillin
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extended range penicillin- a beta lactam
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amoxicillin
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extended range penicillin- a beta lactam
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carbenicillin
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an anti-pseudomonal penicillin carboxylated derivative of amoxicillin- a beta lactam
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ticarcillin
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an anti-pseudomonal penicillin carboxylated deriviative of amoxacillin- a beta lactam
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azlocillin
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anti-pseudomonal penicillin N-acyl derivative (ureidopencillin)
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mezlocillin
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anti-pseudomonal penicillin N-acyl derivative (ureidopencillin)
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pipericillin
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anti-pseudomonal penicillin N-acyl derivative (ureidopencillin)
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augmentin
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amoxicillin + clavulanate
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timentin
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ticarcillin + clavulanate
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unasyn
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ampicillin + sulbactam
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zosyn
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pipericillin + tazobactam
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cefadroxil
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1st gen cephalosporin- a beta lactam
inhbit cell wall synthesis |
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cephalexin
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1st gen cephalosporin- a beta lactam
inhibit cell wall synthesis |
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cefazolin
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1st gen cephalosporin- a beta lactam
inhbit cell wall synthesis |
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cephadrine
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1st gen cephalosporin- a beta lactam
inhbit cell wall synthesis |
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cefotetan
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2nd gen cephalosporin
- a beta lactam inhibits cell wall synthesis INC activity against gram neg DEC activity against gram pos |
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cefoxitin
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2nd gen cephalosporin
- a beta lactam inhibits cell wall synthesis INC activity against gram neg DEC activity against gram pos |
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cefuroxime
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2nd gen cephalosporin
- a beta lactam inhibits cell wall synthesis INC activity against gram neg DEC activity against gram pos |
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cefuroxime axetil
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2nd gen cephalosporin
- a beta lactam inhibits cell wall synthesis INC activity against gram neg DEC activity against gram pos |
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carbacephem
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2nd gen cephalosporin
- a beta lactam inhibits cell wall synthesis INC activity against gram neg DEC activity against gram pos |
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cefotaxime
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3rd gen cephalosporin
- a beta lactam inhibits cell wall synthesis Good CNS penetration |
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cefpodoxime
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3rd gen cephalosporin
- a beta lactam inhibits cell wall synthesis Good CNS penetration |
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ceftazidime
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3rd gen cephalosporin
- a beta lactam inhibits cell wall synthesis Good CNS penetration |
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ceftriaxone
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3rd gen cephalosporin
- a beta lactam inhibits cell wall synthesis Good CNS penetration |
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cefepime
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4th gen cephalosporin
-a beta lactam inhibits cell wall synthesis |
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imipenem
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carbapenem
-a beta lactam inhibits cell wall synthesis |
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meropenem
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carbepenem
-a beta lactam inhibits cell wall synthesis |
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ertapenem
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carbepenem
-a beta lactam inhibits cell wall synthesis |
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monobactam
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carbepenem
-a beta lactam inhibits cell wall synthesis |
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daptomycin
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lipopeptide
inhibit cell membrane potential |
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linezolid
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oxazoladinone
inhibit protein synthesis (binds 23S and prevents formation of 70S) |
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tetracycline
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tetracycline
inhibit protein synthesis (bind 30S and prevent binding of aminoacyl-tRNA during protein synthesis) |
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doxycycline
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tetracycline
inhibit protein synthesis (bind 30S and prevent binding of aminoacyl-tRNA during protein synthesis) |
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minocycline
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tetracycline
inhibit protein synthesis (bind 30S and prevent binding of aminoacyl-tRNA during protein synthesis) |
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streptomycin
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aminoglycoside
inhibit protein synthesis (bind 30S- irreversibly inhibit protein synthesis) |
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neomycin
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aminoglycoside
inhibit protein synthesis (bind 30S- irreversibly inhibit protein synthesis) |
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gentamycin
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aminoglycoside
inhibit protein synthesis (bind 30S- irreversibly inhibit protein synthesis) |
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kanamycin
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aminoglycoside
inhibit protein synthesis (bind 30S- irreversibly inhibit protein synthesis) |
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tobramycin
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aminoglycoside
inhibit protein synthesis (bind 30S- irreversibly inhibit protein synthesis) |
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sisomicin
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aminoglycoside
inhibit protein synthesis(bind 30S- irreversibly inhibit protein synthesis) |
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amikacin
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aminoglycoside
inhibit protein synthesis (bind 30S- irreversibly inhibit protein synthesis) |
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netilmicin
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aminoglycoside
inhibit protein synthesis (bind 30S- irreversibly inhibit protein synthesis) |
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chloramphenicol
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bind 50S
inhibit protein synthesis |
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macrolide
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MLS group
inhibit protein synthesis |
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lincosamide
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MLS group
inhibit protein synthesis |
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type B streptogramins
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MLS group
inhibit protein synthesis |
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ketolide
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MLS group
inhibit protein synthesis |
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erythromycin
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macrolide
-MLS group inhibit protein syntheis (binds 50S and inhibits translocation) |
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clarithromycin
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macrolide
-MLS group inhibit protein syntheis (binds 50S and inhibits translocation) |
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azithromycin
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macrolide
-MLS group inhibit protein syntheis (binds 50S and inhibits translocation) |
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clindamycin
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lincosamide
-MLS group inhibits protein synthesis (binds P and A site in 50S) |
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synecid
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combo of streptogramin B with streptogramin A
inhibits protein synthesis |
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quinupristin
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streptogramin B
-MLS group inhibits protein synthesis (binds 50S and inhibits translocation) |
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dalfopristin
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streptogramin A
inhibits protein synthesis (induces conformation change in 50S, enhancing binding of quinupristin) |
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telithromycin
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ketolide
-MLS group inhibits protein synthesis |
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sulfisoxazole
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sulfonamide
inhibit nucleic acid synthesis (compete w/ PABA for dihydropteroate synthase) |
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sulfamethoxazole
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sulfonamide
inhibit nucleic acid synthesis (compete w/ PABA for dihydropteroate synthase) |
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trimethoprim
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benzylpyrimidine
inhibit nucleic acid synthesis (inhibits bacterial dihydrofolate reductase) |
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pyrimethamine
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benzylpyrimidine
inhibit nucleic acid synthesis (inhibits bacterial dihydrofolate reductase) |
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norloxacin
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fluoroquinolone
inhibits DNA gyrase in gram neg inhibits topoisomerase in gram pos |
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ciprofloxacin
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fluoroquinolone
inhibits DNA gyrase in gram neg inhibits topoisomerase in gram pos |
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ofloxacin
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fluoroquinolone
inhibits DNA gyrase in gram neg inhibits topoisomerase in gram pos |
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levofloxacin
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fluoroquinolone
Inhibits nucleic acid synthesis (inhibits DNA gyrase in gram neg inhibits topoisomerase in gram pos) |
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lomefloxacin
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fluoroquinolone
Inhibits nucleic acid synthesis (inhibits DNA gyrase in gram neg inhibits topoisomerase in gram pos) |
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sparfloxacin
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fluoroquinolone
Inhibits nucleic acid synthesis inhibits DNA gyrase in gram neg inhibits topoisomerase in gram pos |
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pefloxacin
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fluoroquinolone
inhibits DNA gyrase in gram neg inhibits topoisomerase in gram pos |
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metronidazole
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nitroimidazole
inhibit DNA replication (nucleic acid synthesis) |
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rifaximin
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rifamycin
inhibits nucleic acid synthesis (inhibits bacterial RNA synthesis) |
