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4 Cards in this Set
- Front
- Back
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SLE diagnostic criteria
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Arthritis
Rash ANA +ve Serositis (Pleuritis/Pericarditis) Haematological - Leukopenia, Anaemia, Lymphopenia, Thrombocytopenia Photosensitivity Oral ulcers Immunological - Anti-dsDNA, Anti-Sm, Antiphospholipid Neuro - Seizures Malar rash Discoid rash >4 is diagnostic |
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Risk factors for SLE
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0.2% prevalence
Females > Males 9:1 HLA DR2/DR3/8 Afro-Caribbean, Asian 10% of relatives May be triggered by EBV |
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Clinical features of SLE
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Remitting-Relapsing condition
Malaise Fever Fatigue Myalgia Malar/Discoid rash Signs of Non-infective endocarditis Nail fold infarcts Migraine Photosensitivity, oral ulcers, arthritis, seizures raynaud's, stroke |
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Investigations for SLE
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ANA +ve (95%)
Anti-dsDNA Anti-phospholipid Anti-La, anti-Sm, anti-rnp, anti-ro |
