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25 Cards in this Set
- Front
- Back
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systemic JRA early sx
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fever to 102 multiple times a day for weeks. rash which comes with fever. generalized lymphadenopathy. very high WBC 30-50. Joint sx occur at same time or later
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dermatomyositis signs
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purple malar rash, gottron papules (rash over knuckles), nail fold telangiectasias, prox muscle weakness.
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initial labs for dermatomyositis
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CK, aldolase, AST, ALTk LDH
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cutis laxa
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skin too big for body. rare. not hyperextensbile. no joint laxity
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SLE thrombolembolic disease
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lupus anticoagulant, prolong PTT, paradoxically causes venous or arterial thromboses.
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most common renal manifestations of SLE
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hematuria, proteinuria, HTN
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SLE sx
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renal, rash, arthralgia/arhtritis, pallor, hemorrhage, nuero, cardiac, muscle, pleural effusions, HS megaly. photosensitivity.
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SLE labs
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low C3, low C4
ANA positive 90% antiDS DNA Ab specific to SLE |
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SLE dx criteria
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Serositis
Oral ulcers Arthritis Photosensitivity Blood Renal ANA Immunologic Neurologic Malar rash Discoid |
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scleroderma types
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localized more common than systemic
localized: indurated skin surrounded by purple halo color cahnges to waxy or ivory appearance, atrophic and hypopigmented. |
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Localized scleroderma types
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linear: band like distribution (self limited, 3-5yrs)
morphea: 1-2 lesions, trunk generalized morphea: widespread coalexcent lesions |
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lichen sclerosus et atrophicus
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hypopigmented areas atrophic not sclerotic. genitalia.
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cardiac complicatins of JRA
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pericarditis with sterile pericardial effusion. chest pain lasting al day and night
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treatment for scleroderma
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observation, photo-chemotherapy if progressive
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ITP that does not go away
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chronic ITP. many go on to have SLE
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treatment for SLE nephritis
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prednisone 2mg/kg
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SLE maintenance labs
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always do urinalysis. frequently do ANA, anti DS DNA, C3 C4.
Low C3 C4 and hi ANA, DS-DNA are active disease normal C3 C4 shows response to therapy. |
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intermittent unilat lower extremity pain. morning stiffness relieved by exercise.
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Ankylosing spondylitis. hip ankle sarthritis, inflammation of small joints of feet. local tenderness at achilles. SI joint arthitis and lumbar spine flatening.
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ankylosing spondylitis labs
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HLA-B27 +
all other Rheum labs are neg. |
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girl with asymetric oligoarthritis, large and small joints.
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psoriatic arthritis. HLA-B27, nail pitting, FH of psoriasis.
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teen boy with knee arthitis adn abnormal axial skeleton. loss of spinal fexibility
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ankylosing spondylitis
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pyoderma gangrinosum
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IBD rash. pustules on skin, coalesce into deep necrotoic lesions. elbows.
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postinfecious arthritis agents
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Shigella, salmonella, Yersinia, Camplobacter. all cause bloody diarrhea and weeeks later arthritis. Chlamydia t., GAS (usually symmetric arthtitis, prolonged, persistant
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conjunctivitis, arthritis, non-bacterial urethritis, painless ulcers in mouth
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Reiter syndrome. autoimmune response to STD, Chlamydia most typically. HLA B27 is risk factor.
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african american chld fatigue, weight loss, fever, cough, bilateral peribronchial infiltrates
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Sarcoidosis. noncaseating granulomatous disease. chronic resp sx.
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