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35 Cards in this Set

  • Front
  • Back

External Respiration

Exchange of gas in the lungs

Internal respiration

exchange of gas at the cellular level

Muscles involved in respiration

Diaphragm and intercostal muscles

Boyle's Law

Pressure and Volume are inversely proportional

Eupnea

Normal breathing

Apnea

Absence of breathing

Dyspnea

Difficult Breathing

Hyperpnea

increase in rate and depth of breathing

Polypnea

shallow and rapid breathing

Tidal volume

the volume of air inspired or expired with each normal breath, at rest.

Inspiratory reserve volume

It is the volume of the air that can be inspired beyond the normal tidal volume.

Experitory reserve volume

the amount of air that can be still expired out by forceful expiration after the end of normal expiration.

Residual volume

the volume of the air still remaining in the lungs after the most forceful expiration.

Minute Volume

defined as the total amount of air breathed each minute. It is equal to tidal volume X respiration rate.

Total lung capacity

the maximum volume of lung expansion during maximum inspiratory effort

Vital Capacity

the greatest volume of air that can be exchanged during a single respiratory cycle

Anatomical dead space

Respiratory pathway except alveoli, no gas exchange occurs here

What creates the physiological dead space in lungs?

Panting, creating "dead" alveoli

Partial Pressure

pressure of gas exerted by individual gas in a mixture of gases
Partial pressure of Oxygen is highest in which organ?

Lung Alveoli

Partial pressure of Oxygen is lowest in which organ?

Body tissue

pressure of gas exerted by individual gas in a mixture of gases

Body tissues

Partial pressure of CO2 is lowest in which part of body?

Lung Alveoli

How gasses are transported in blood

-dissolved in plasma
-chemically combined with hemoglobin
-converted into different molecules
How is the oxygen carried in the blood?
1.5% oxygen is dissolved in blood, while rest 98.5 % of the oxygen is transported bound to hemoglobin and is called oxyhemoglobin
A drop in partial pressure to what level, would significantly affect the oxygen saturation of hemoglobin.

Below 60 mmHg

What is Bohr's effect?
As at tissue level, pCO2 is highest, it will decrease the pH at tissue level. The pO2 is lowest at tissue level. All these factors decrease the Hb affinity for oxygen, and will help the oxyhemoglobin to release the oxygen at tissue level.
-List the three ways, the carbon dioxide enter the blood from the tissues.
1. About 7% carbon dioxide gets dissolved in blood
2. About 23% of carbon dioxide enters in RBCs and combines with hemoglobin to form carbamino-hemoglobin.
3. Rest 70% carbon dioxide also enters the RBCs and combines with water (H2O) to form carbonic acid (H2CO3).
enzyme present in RBCs, that is responsible for hydration of CO2 into carbonic acid.
carbonic anhydrase
Name the respiratory centers present in medulla and pons of the brain
In medulla, there are two centers: 1. Inspiratory Center 2. Expiratory Center.
In pons, there is pneumotaxic center.
main function of inspiratory center
these centers initiates the impulses for inspiration.
main function of expiratory center
neurons only fire impulses when extra expiratory effort is needed during forced expiration like defecation and parturition etc.
What is the function of pneumotaxic center
to inhibit the inspiratory center and allow passive expiration, once inspiration is completed.
The Hering-Breuer Reflex
This limits further inspiration and serves as a protective mechanism for preventing excess lung inflation
central chemoreceptors located in brain

Central and peripheral centers