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25 Cards in this Set
- Front
- Back
PaO2 trend with age?
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It decreases by 4 with each decade after 20yo
i.e. 20 = 96-104 30 = 92-100 60 = 79-87 etc |
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Equation for amount of O2 dissolved in plasma?
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PaO2 x .003
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Equation for amount of O2 bound to Hb?
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Hb x 1.34 x SaO2
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Normal Arterial Oxygen Content = ??
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~20vol%
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Normal amount of O2 bound to Hb?
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19.7 mL
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Normal amount of O2 in plasma?
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0.3mL
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Effect on Arterial Oxygen Content by increasing PaO2 5 fold?
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it increases to 21.2 vol%
which ain't much. this is why oxygen bars aren't worth your money |
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Delivered O2 is equal to???
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Oxygen Content x Cardiac Output
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What is normal DO2?
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1000mL/min
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When is hyperbaric O2 indicated?
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carbon monoxide poisoning
smoke inhalation |
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Define Hypoxia?
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deficiency of O2 getting to tissues
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Types of Hypoxia?
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Histologic
Anemic Circulatory/Stagnant |
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Define Histologic Hypoxia?
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cells are unable to utilize O2
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When might histologic hypoxia occur?
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Cyanide Poisoning
Septic Shock |
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Define Anemic Hypoxia?
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When Hb concentration is lower than normal and unable to transport O2
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When might anemic hypoxia occur?
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Sickle Cell
CO poisoning metHb |
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Define Circulatory Hypoxia?
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When the CV system fails to transport O2 to tissues, usually b/c of low Cardiac Output
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Difference between hypoxia and hypoxemia?
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Hypoxemia is a reduction in the partial pressure of O2 in the blood.
This leads to hypoxia |
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Causes of Hypoxemia?
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Shunting
V/Q mismatching Diffusion Defects Hypoventilation |
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Normal Arterial Blood Gas numbers?
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pH = 7.35-7.45
PaCO2 = 35-45 PaO2 = 80-100 HCO3 = 22-24 |
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In general, as PaCO2 increases by 1, what happens to PaO2?
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it decreases by 1.25
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What is CPAP?
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Continuous Positive Airway Pressure
its like sticking your head out of the car at 60mph |
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When do we use CPAP?
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Obstructive sleep apnea
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PO2 + PCO2 = between 110 and 130
AND the patient is hypoxemic CAUSE? |
Hypoventilation
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PO2 + PCO2 < 110
CAUSE? |
V/Q Mismatch
Diffusion Defect Shunt |