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4 Cards in this Set
- Front
- Back
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Increase GFR
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Increase flow rate in nephron
Less chance to passively equilibriate Na+ in tALH, more Na+ reaches dist. tubule so therefore more Na+ reabsorbtion via NaCl cotransporter Increased Na+ to Macular densa Release adenosine, causes afferent arteriole constriction (decrease GFR) and renin release |
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Renins effects
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Its an enzyme, catalyses Angiotensinogen to A1,
A1 then converted to A2 (vasoconstrictor) by ACE in lungs A2 acts on AT1 receptor to induce aldosterone release from Z Glomerulosa. inc ENaC and NaKATPase |
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ANP
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Atrial Natriuretic peptide
Released from atria on stretch (high circ. volume) Increases cGMP in cells Reduce renin output Increase GFR by contricting efferent arteriole Inhibits aldosterones action |
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Nephrotic syndrome
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Breakdown of BM of capillary endothelium in Glomerulus occurs - Proteinuria results
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